ID M7PEE5_9GAMM Unreviewed; 369 AA.
AC M7PEE5;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=RND family efflux transporter, MFP subunit {ECO:0000313|EMBL:EMR12255.1};
GN ORFNames=MPL1_11248 {ECO:0000313|EMBL:EMR12255.1};
OS Methylophaga lonarensis MPL.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC Piscirickettsiaceae; Methylophaga.
OX NCBI_TaxID=1286106 {ECO:0000313|EMBL:EMR12255.1, ECO:0000313|Proteomes:UP000012019};
RN [1] {ECO:0000313|EMBL:EMR12255.1, ECO:0000313|Proteomes:UP000012019}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MPL {ECO:0000313|EMBL:EMR12255.1,
RC ECO:0000313|Proteomes:UP000012019};
RX PubMed=23661481;
RA Shetty S.A., Marathe N.P., Munot H., Antony C.P., Dhotre D.P.,
RA Murrell J.C., Shouche Y.S.;
RT "Draft Genome Sequence of Methylophaga lonarensis MPLT, a Haloalkaliphilic
RT (Non-Methane-Utilizing) Methylotroph.";
RL Genome Announc. 1:E00202-13(2013).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMR12255.1}.
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DR EMBL; APHR01000063; EMR12255.1; -; Genomic_DNA.
DR RefSeq; WP_009727204.1; NZ_APHR01000063.1.
DR AlphaFoldDB; M7PEE5; -.
DR STRING; 1286106.MPL1_11248; -.
DR PATRIC; fig|1286106.3.peg.2248; -.
DR eggNOG; COG0845; Bacteria.
DR OrthoDB; 9806939at2; -.
DR Proteomes; UP000012019; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR PANTHER; PTHR30469:SF37; RAGD PROTEIN; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000012019};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..369
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004082828"
FT DOMAIN 71..284
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
SQ SEQUENCE 369 AA; 41078 MW; 27FFE57C72D2AB18 CRC64;
MKFSITTASL SLTTLAVLGA IMLNSPNNTA TAAASNQSDD ISLPRVTIVQ PEPVNSAQPY
QFNARLEAIE SAHVFARADG YIENRFVDIG DEVSQGQLLA QLSSPELEEQ IRQAKAEINR
QQAVVHLSKK MSDRVSRLQG SGAVTQTEVD EKDAEYQVAL ATLETYQARL EQLENEFAYT
RIVAPFDGII TVRNVDRGDR ITRNDSQALF RIVRTDELRV LVDIPQTQLY SIDQNQQATL
LIPELASQSF EVNFSRMSRE IDNTLGTMRL EYLLDNADQQ LSAGLSGRLR IPASTTDRLQ
IPINAVKILN GESVVMTVDQ EDRLQQRPVV TGRYNSHRVE IRNGLSTQDR VVLNPNALLK
TGDRVAINE
//
