ID   M7SIB8_EUTLA            Unreviewed;       740 AA.
AC   M7SIB8;
DT   29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 48.
DE   SubName: Full=Putative glutamate carboxypeptidase protein {ECO:0000313|EMBL:EMR66064.1};
GN   ORFNames=UCREL1_6954 {ECO:0000313|EMBL:EMR66064.1};
OS   Eutypa lata (strain UCR-EL1) (Grapevine dieback disease fungus) (Eutypa
OS   armeniacae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Xylariomycetidae; Xylariales; Diatrypaceae; Eutypa.
OX   NCBI_TaxID=1287681 {ECO:0000313|EMBL:EMR66064.1, ECO:0000313|Proteomes:UP000012174};
RN   [1] {ECO:0000313|Proteomes:UP000012174}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UCR-EL1 {ECO:0000313|Proteomes:UP000012174};
RX   PubMed=23723393; DOI=10.1128/genomeA.00228-13;
RA   Blanco-Ulate B., Rolshausen P.E., Cantu D.;
RT   "Draft genome sequence of the grapevine dieback fungus Eutypa lata UCR-
RT   EL1.";
RL   Genome Announc. 1:E0022813-E0022813(2013).
CC   -!- SIMILARITY: Belongs to the peptidase M28 family. M28B subfamily.
CC       {ECO:0000256|ARBA:ARBA00005634}.
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DR   EMBL; KB706718; EMR66064.1; -; Genomic_DNA.
DR   RefSeq; XP_007794846.1; XM_007796655.1.
DR   AlphaFoldDB; M7SIB8; -.
DR   KEGG; ela:UCREL1_6954; -.
DR   eggNOG; KOG2195; Eukaryota.
DR   HOGENOM; CLU_005688_2_0_1; -.
DR   OMA; TEWMEEY; -.
DR   OrthoDB; 67337at2759; -.
DR   Proteomes; UP000012174; Unassembled WGS sequence.
DR   GO; GO:0004180; F:carboxypeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd08022; M28_PSMA_like; 1.
DR   CDD; cd02121; PA_GCPII_like; 1.
DR   Gene3D; 3.50.30.30; -; 1.
DR   Gene3D; 1.20.930.40; Transferrin receptor-like, dimerisation domain; 1.
DR   Gene3D; 3.40.630.10; Zn peptidases; 1.
DR   InterPro; IPR046450; PA_dom_sf.
DR   InterPro; IPR007484; Peptidase_M28.
DR   InterPro; IPR039373; Peptidase_M28B.
DR   InterPro; IPR007365; TFR-like_dimer_dom.
DR   InterPro; IPR036757; TFR-like_dimer_dom_sf.
DR   PANTHER; PTHR10404:SF46; GLUTAMATE CARBOXYPEPTIDASE 2 HOMOLOG; 1.
DR   PANTHER; PTHR10404; N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE; 1.
DR   Pfam; PF04389; Peptidase_M28; 1.
DR   Pfam; PF04253; TFR_dimer; 1.
DR   SUPFAM; SSF52025; PA domain; 1.
DR   SUPFAM; SSF47672; Transferrin receptor-like dimerisation domain; 1.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE   3: Inferred from homology;
KW   Carboxypeptidase {ECO:0000313|EMBL:EMR66064.1};
KW   Hydrolase {ECO:0000313|EMBL:EMR66064.1};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Protease {ECO:0000313|EMBL:EMR66064.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000012174}.
FT   DOMAIN          378..563
FT                   /note="Peptidase M28"
FT                   /evidence="ECO:0000259|Pfam:PF04389"
FT   DOMAIN          627..739
FT                   /note="Transferrin receptor-like dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF04253"
FT   REGION          263..307
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        271..290
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   740 AA;  79922 MW;  86CFD6398245F14B CRC64;
     MHNVTSSTKY STDIVSTIWQ VKITATSQLN VTATVIPRIS PHVDPGLWSK VGTVKRQDSR
     QIPLKLEDSP DGPGLSLNSD ERTLVESVSN TTLSGWSYYY THGDHVAGRN RTMAQWTADR
     FAESGINSSV VSYNVYLNYP VNKSLTLTWS NGTIYEPSLE EDVLSEDDTS SYPNRIPTFH
     GYSASGSASA EYVYVGRGQQ VDFERLVELG VPLEGKIAIA KYGGPFRGLK VKNSQDYGLV
     GTVIFTDPGD DGNVTEANGY AAYPDGPARN PSSVQRGSVQ FLSTYPGDPT TPGYPSKPGS
     PRADKSPVVP RIPSIPISYQ DAIPILAALD GYGTAGDVVN RTGWVGALNV SYSTGPAPGA
     TLSLSNLMDE QYTDIWDTIG VINGTNTNET IIIGNHRDAW IVGGAADPNS GSAVLVELSK
     AFGKLLAQGW KPKRNIVLAS WDAEEYGLVG STEWVEEYIP WLTDTAVSYL NIDVGTAGPH
     PDISATPELH TIAIDTMKKI LWRDTGRTMY DVWYDDFEGE VGVLGSGSDY TAFVHNGIGS
     IDLGSGGGAT DPVYHYHSNF DSYHWMATYG DPGFLSHKSM AQYLSLLAYN IAAPDLIPFD
     LPNYATQLET YYESLTSTIS SASADLDISA LRGAIDEFAG RTAEVKAQEQ QALSTDDSGL
     LTLVNQKYRD FQRGFVSQGG LPNRTFYKHL IFAPGLDTGY APTTFPGITE AVESGNLTLA
     TEFVKKTADA ITKAGDILKA
//