ID   M7SJJ2_EUTLA            Unreviewed;      1374 AA.
AC   M7SJJ2;
DT   29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 55.
DE   SubName: Full=Putative polyketide synthase protein {ECO:0000313|EMBL:EMR64483.1};
GN   ORFNames=UCREL1_8555 {ECO:0000313|EMBL:EMR64483.1};
OS   Eutypa lata (strain UCR-EL1) (Grapevine dieback disease fungus) (Eutypa
OS   armeniacae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Xylariomycetidae; Xylariales; Diatrypaceae; Eutypa.
OX   NCBI_TaxID=1287681 {ECO:0000313|EMBL:EMR64483.1, ECO:0000313|Proteomes:UP000012174};
RN   [1] {ECO:0000313|Proteomes:UP000012174}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UCR-EL1 {ECO:0000313|Proteomes:UP000012174};
RX   PubMed=23723393; DOI=10.1128/genomeA.00228-13;
RA   Blanco-Ulate B., Rolshausen P.E., Cantu D.;
RT   "Draft genome sequence of the grapevine dieback fungus Eutypa lata UCR-
RT   EL1.";
RL   Genome Announc. 1:E0022813-E0022813(2013).
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DR   EMBL; KB707064; EMR64483.1; -; Genomic_DNA.
DR   RefSeq; XP_007796432.1; XM_007798241.1.
DR   STRING; 1287681.M7SJJ2; -.
DR   KEGG; ela:UCREL1_8555; -.
DR   eggNOG; KOG1202; Eukaryota.
DR   HOGENOM; CLU_000022_31_8_1; -.
DR   OMA; EYEASGH; -.
DR   OrthoDB; 5396558at2759; -.
DR   Proteomes; UP000012174; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR   GO; GO:0044249; P:cellular biosynthetic process; IEA:UniProt.
DR   GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR   GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   CDD; cd05195; enoyl_red; 1.
DR   Gene3D; 1.10.1200.10; ACP-like; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   Gene3D; 3.10.129.110; Polyketide synthase dehydratase; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR036736; ACP-like_sf.
DR   InterPro; IPR013217; Methyltransf_12.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR042104; PKS_dehydratase_sf.
DR   InterPro; IPR049551; PKS_DH_C.
DR   InterPro; IPR020843; PKS_ER.
DR   InterPro; IPR013968; PKS_KR.
DR   InterPro; IPR020806; PKS_PP-bd.
DR   InterPro; IPR009081; PP-bd_ACP.
DR   InterPro; IPR006162; Ppantetheine_attach_site.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR43775:SF29; ASPERFURANONE POLYKETIDE SYNTHASE AFOG-RELATED; 1.
DR   PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR   Pfam; PF13602; ADH_zinc_N_2; 1.
DR   Pfam; PF08659; KR; 1.
DR   Pfam; PF08242; Methyltransf_12; 1.
DR   Pfam; PF00550; PP-binding; 1.
DR   Pfam; PF14765; PS-DH; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SMART; SM00822; PKS_KR; 1.
DR   SMART; SM00823; PKS_PP; 1.
DR   SUPFAM; SSF47336; ACP-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   PROSITE; PS50075; CARRIER; 1.
DR   PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE   4: Predicted;
KW   Multifunctional enzyme {ECO:0000256|ARBA:ARBA00023268};
KW   Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000012174}.
FT   DOMAIN          1284..1362
FT                   /note="Carrier"
FT                   /evidence="ECO:0000259|PROSITE:PS50075"
SQ   SEQUENCE   1374 AA;  149955 MW;  931EFFD38FC3545E CRC64;
     MCQKAAATGR LIAGYELRDV IISKAIVVPE DDSGVETMLT LKPFRLGSQA LTASWQEFQL
     YSRTEDWELN CSGLIRVDYE TEKNPTFADE DALEAKRHSL RHQQIREDCP RSQNPRQFYD
     NLGAIGLYYG GVFQSLHEIR KGDFKAAGRV KIPDTRKTMP HQFEFSHVIH PATLDNIVQL
     ALPASTPVDE DLTSELLGFD DGESTIVVSD ETWNTPLVII EGLKGKKLSQ MDNAESDVSL
     RKLGTYFKWQ PDLTLLDSRQ ARDLCLRAVG TLGQVDRQVL IEIEIACFLL AEQGKLCYQD
     ETRSLDWLTM PVEEEDELLA RVADSSTDGA ALVEHGAYLP QILRGKVPPL QVLMRDNFLH
     NFYQSGLGTA QHYAQMSSYI DLEAHKNPTM KILEIGGGTA GATLPILNAL GGSNGTSPRF
     AKYTFTDISV GFFEKAREKL APWTPYMNFA KLNIENDPVE QGFEEGGYDI IVASNVLHAT
     RYIGETLANV RRLLKPGGKL VLTEVTNSSR KMRFHMIVGS LEGWWYGGND GRHLGPTLDL
     QQWHSALLDA GFSGIKVDLP DFQDPQDVGL SVIISGASAP APLPSLEHAV VVVPDTSTPE
     IDACAAKLAR KLQKKGTQVT VSSLSETKDM ELENQSCLCL VDARKDMGFL PDISESNWES
     LKRVILTCRD VTYITRGGTV NSENPSTNLM TGMARSIRSE EHALLLTTVD LGWETALDDD
     ENIIVPLLKI FQASSVAETD EKWKDREYAI RDGIPKIQRV LLEENINELA ATCAGAGCHG
     ATHLGTEWHD GMGDGGLVAS HLQHGALRTV HTARLQKGES VLIHGAAGGV GQAAIMLAQY
     IGATILATVS TEAKKKMLME TYGIPSAHIL NSRDSIAFSQ AVSRLTNGRG VDVVLNSLAG
     EPLRASWCAI ARFGRFVELG QRDIAGNTGL DMGPFIRNVS FHSVNMLDLL DHDLDAAARA
     FSEAVELLRK GAVRPVTPIT AMPFSRAEEA FRLMQTGKHT GKIVLQVQED DVVPIVPAAI
     PPVRLTPDAT YVIAGGGGGL ARALAEWMVK SGARHILLLT RSGTKKESTR DLIRRLTKQG
     AQVAAWECDV GNENSLVGAL ARCQAESWPP IKGVVQGAMV LNDAIYQNMT RQQFFDATRP
     KVQGSWYLHQ HLPRDMDFFI LLSSSVGIAG SRGQGNYSAG NTYEDALAHH RRGLSLPACS
     IDLGMVLGVG FLAEESTENR VHDNVKSWNF LGIREHEFLG VMDACIRGES QPGVPVPPQL
     ITGLGTGGMM AHGATKYPLA ANLEEAVDVV SDVLVSKLAK SLMVATEDIE VTRPISGYGV
     DSLLAVELRA WIFSEIKAEV SVFELLSNEP ITALARKIAT KSKAVPEAFV NGGS
//