ID M7TAU2_EUTLA Unreviewed; 901 AA.
AC M7TAU2;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Putative serin endopeptidase protein {ECO:0000313|EMBL:EMR63765.1};
GN ORFNames=UCREL1_9275 {ECO:0000313|EMBL:EMR63765.1};
OS Eutypa lata (strain UCR-EL1) (Grapevine dieback disease fungus) (Eutypa
OS armeniacae).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Xylariomycetidae; Xylariales; Diatrypaceae; Eutypa.
OX NCBI_TaxID=1287681 {ECO:0000313|EMBL:EMR63765.1, ECO:0000313|Proteomes:UP000012174};
RN [1] {ECO:0000313|Proteomes:UP000012174}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UCR-EL1 {ECO:0000313|Proteomes:UP000012174};
RX PubMed=23723393; DOI=10.1128/genomeA.00228-13;
RA Blanco-Ulate B., Rolshausen P.E., Cantu D.;
RT "Draft genome sequence of the grapevine dieback fungus Eutypa lata UCR-
RT EL1.";
RL Genome Announc. 1:E0022813-E0022813(2013).
CC -!- SIMILARITY: Belongs to the peptidase S8 family. {ECO:0000256|PROSITE-
CC ProRule:PRU01240, ECO:0000256|RuleBase:RU003355}.
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DR EMBL; KB707177; EMR63765.1; -; Genomic_DNA.
DR RefSeq; XP_007797134.1; XM_007798943.1.
DR AlphaFoldDB; M7TAU2; -.
DR KEGG; ela:UCREL1_9275; -.
DR eggNOG; KOG4266; Eukaryota.
DR HOGENOM; CLU_003559_3_1_1; -.
DR OMA; PCVIANG; -.
DR OrthoDB; 662485at2759; -.
DR Proteomes; UP000012174; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd02124; PA_PoS1_like; 1.
DR CDD; cd07489; Peptidases_S8_5; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 2.
DR Gene3D; 2.60.40.1710; Subtilisin-like superfamily; 1.
DR InterPro; IPR010435; Fn3_5.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023827; Peptidase_S8_Asp-AS.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR034187; Peptidases_S8_5.
DR PANTHER; PTHR43399; SUBTILISIN-RELATED; 1.
DR PANTHER; PTHR43399:SF4; TK-SUBTILISIN; 1.
DR Pfam; PF06280; fn3_5; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00136; SUBTILASE_ASP; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000012174};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..901
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004085692"
FT DOMAIN 163..582
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT DOMAIN 624..740
FT /note="Fn3-like"
FT /evidence="ECO:0000259|Pfam:PF06280"
FT REGION 110..147
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 116..134
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 172
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 223
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 548
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 901 AA; 94849 MW; 40F2A73F2CF9880A CRC64;
MRIATSGLAL LGLLSSSSVV TAAVEVKDDS IVPGAYIVEF NEGADANSLY DELRADGVAL
EHRVDLNYRL FKGASFRLSN ASASEPDVVA NQIYGKAHVK QIWPVRGIQF PKPEPRSVGR
NSTSTSSTTA QQQRRQEAEE GEDTYSPHVM AQVDKLRAEG LTGKGIRIGV VDTGIDYNHP
ALGGCFGEGC LVGYGWDLTG DDYSEGSDAP TPDADPYDSC QGHGTHVAGI VMAQPNELGF
TGVAPDVTLG MYKVSGCAGY TTNEILIAAF NQAYEEGSDI ISCSAGDDSG WANDPWAVAA
SRIADAGVPV VVALGNSGNL GVWTTASPAS GLSVAGIGSA HNTVLPTIVT AASWSSNGTD
TKFGWREGVP SLAETNLTLP LWAASYNTTA EDDACEPLPD DTPDLSTRIT LLRKASACNY
DDQALNVAAK GGKYIMFYMA DNENIETPYV YTDGILGTGS VTVKQGAEWV ETLSAGENVT
LNMVEAASAR LAVVDLSNGP AAGYTSPFTS WGPTWEVEVK PQFITPGGWI LSTFPLEQGE
YAVNPGTSMA CPFAAAVFAL VAEKRGTFDA KILRNILAAT SKPNLWNDET KAYDLLAPVA
QQGAGLIQAY DAAFATVIPS VSSISFNDSD HFVGNHSFSL DNTGSEDVTF TLGHAKSVTV
YSFGLETLSA ARFPPPTVEG YAEITFEADE ITVPAGGSAE VAFTAEPPSS AGLNATLLPV
YGGYITLNGT NGDTLSIPYL GVAGSLHDTP VLRPWFNENG GSGGVFLTST DSHFNIPVAA
NTTFTIPRPG TSGTAAFPQL LLLPTIGSTE LHIDVVPLGN TSLPTYDWLG MKSVGQLPQL
PLNFVPRTGY TFNFGGRLAD GSAVDEGQYT LVASALKIFG DADKTEDWSV VETVPFTLRY
L
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