ID   M7TDU1_EUTLA            Unreviewed;      1246 AA.
AC   M7TDU1;
DT   29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 52.
DE   SubName: Full=Putative pre-mrna-splicing factor atp-dependent rna helicase prp22 protein {ECO:0000313|EMBL:EMR68066.1};
GN   ORFNames=UCREL1_4930 {ECO:0000313|EMBL:EMR68066.1};
OS   Eutypa lata (strain UCR-EL1) (Grapevine dieback disease fungus) (Eutypa
OS   armeniacae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Xylariomycetidae; Xylariales; Diatrypaceae; Eutypa.
OX   NCBI_TaxID=1287681 {ECO:0000313|EMBL:EMR68066.1, ECO:0000313|Proteomes:UP000012174};
RN   [1] {ECO:0000313|Proteomes:UP000012174}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UCR-EL1 {ECO:0000313|Proteomes:UP000012174};
RX   PubMed=23723393; DOI=10.1128/genomeA.00228-13;
RA   Blanco-Ulate B., Rolshausen P.E., Cantu D.;
RT   "Draft genome sequence of the grapevine dieback fungus Eutypa lata UCR-
RT   EL1.";
RL   Genome Announc. 1:E0022813-E0022813(2013).
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DR   EMBL; KB706311; EMR68066.1; -; Genomic_DNA.
DR   RefSeq; XP_007792845.1; XM_007794654.1.
DR   AlphaFoldDB; M7TDU1; -.
DR   STRING; 1287681.M7TDU1; -.
DR   KEGG; ela:UCREL1_4930; -.
DR   eggNOG; KOG0920; Eukaryota.
DR   HOGENOM; CLU_001832_4_0_1; -.
DR   OMA; LFRVCNM; -.
DR   OrthoDB; 53793at2759; -.
DR   Proteomes; UP000012174; Unassembled WGS sequence.
DR   GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProt.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd17917; DEXHc_RHA-like; 1.
DR   CDD; cd18791; SF2_C_RHA; 1.
DR   Gene3D; 1.20.120.1080; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 1.
DR   InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR   InterPro; IPR007502; Helicase-assoc_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR006575; RWD_dom.
DR   InterPro; IPR009060; UBA-like_sf.
DR   InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR   PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR   PANTHER; PTHR18934:SF145; ATP-DEPENDENT RNA HELICASE DHX29; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF21010; HA2_C; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF07717; OB_NTP_bind; 1.
DR   Pfam; PF05773; RWD; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00847; HA2; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF46934; UBA-like; 1.
DR   SUPFAM; SSF54495; UBC-like; 1.
DR   PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000313|EMBL:EMR68066.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000012174}.
FT   DOMAIN          513..688
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          763..933
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
SQ   SEQUENCE   1246 AA;  137847 MW;  8A825A5549318889 CRC64;
     MGEARLPTCK DGFSYFVKLG AKHPKTQEMQ TLPPFKLPPD YIHLVTRPTA LEARHAAATY
     ALFRVCSMKR VDTTLPPDYR ALWKQFEELK KEDVKKGNAW LYDADPFVTA RQRESDKAAV
     EKKRKEQEAI REKAKNMPGA AGLVLRGNAA EKGSGGGSNP MKGWTTVPKV EMGKKTRSQL
     EDLLRREVIW NPHGVVMTKA QKDAILKELT GSGFRKSHVE EAVEECKDRE ETLEWLLIHV
     PEDDLPRWAL PGSYSAGVSV AATQDLKREA TIKRLSESGY SAELCRKVLN ENDGDEGRTA
     QALQHFLLSS GDSAEQWKPP DEPFVSGTPE ECWTDEIDSL GSVFGENFNR VSDGVCQIRI
     ESVRNGARNN IETHVQIRKP PRYPAEIIVT IMADLPSYIK LSVIKKTLAY INESLSEEPM
     KIYFAVDWIQ QNINDIIERP GKLRDISGVA STAAEVRSFA PKKRLPRHPK PLAWVVDPRS
     RDEWQRRQEI SKYKEMLAQR QKLPAWQVRE HLVATVAQNQ VTIIAGETGS GKSTQSVQFI
     LDDLYSKGFG NAVNIICTQP RRISALGLAD RVSDERCSQI GKEVGYSIRG ENKVSNETKI
     TFVTTGVLLR RLQTSGGRVE DVVSSLANVS HVVIDEVHER SLDTDFLLSI VRDVLKRRKD
     LKLVLMSATL DAATFRDYFT IEGLGVGLVE IAGRTYPVED YYLDDIIQMT GFTVGNNRFH
     NDRFRDDEGP SDNDDQSKDP INKVIQKLGS RINYSLLLET VKAIDTELHY TSKEKGGAGG
     ILIFLPGVAE ISQAVNHLRS VPALHVLPLH ASLDTRDQRR VFVPPPPGKR KVVVATNVAE
     TSITIDDIVA VVDAGRVKET GFDPATNMRT LEETWASRAA CKQRRGRAGR VQAGTCYKLY
     TRNLETQHMA ERPEPEIRRV PLEQLCLSVR AMGTRDVAGF LARTPTPPET AAVAGAVGTL
     RRMGALDGDE LTALGVQLAA IPADLRCGKL MVHGAIFGCL DECVCIAAIL STRSPFVSPP
     PDKREVAREA RLRFSRGDGD LLTDLRAFQQ WRTATVTGGG GQRQVRQFCD ENFLSFQTLS
     DIAATRVQYY GALAEIGIID ASTARAAASS STASSQEQNN SNMVSMALVR ALTASAFTPQ
     IARIQFPDKK FATSASGAVE LDPEARTIKF FARDSGRVFV HPASALFGAQ AFPGGAAFVS
     YFTLMSTSKI FIRDLTPFNA YTLLLFSGAI ELDTLGRGLV VDGWLR
//