ID   M7TFI1_EUTLA            Unreviewed;       794 AA.
AC   M7TFI1;
DT   29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=Putative vacuolar transporter chaperone 2 protein {ECO:0000313|EMBL:EMR68696.1};
GN   ORFNames=UCREL1_4298 {ECO:0000313|EMBL:EMR68696.1};
OS   Eutypa lata (strain UCR-EL1) (Grapevine dieback disease fungus) (Eutypa
OS   armeniacae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Xylariomycetidae; Xylariales; Diatrypaceae; Eutypa.
OX   NCBI_TaxID=1287681 {ECO:0000313|EMBL:EMR68696.1, ECO:0000313|Proteomes:UP000012174};
RN   [1] {ECO:0000313|Proteomes:UP000012174}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UCR-EL1 {ECO:0000313|Proteomes:UP000012174};
RX   PubMed=23723393; DOI=10.1128/genomeA.00228-13;
RA   Blanco-Ulate B., Rolshausen P.E., Cantu D.;
RT   "Draft genome sequence of the grapevine dieback fungus Eutypa lata UCR-
RT   EL1.";
RL   Genome Announc. 1:E0022813-E0022813(2013).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Vacuole membrane
CC       {ECO:0000256|ARBA:ARBA00004128}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004128}.
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DR   EMBL; KB706192; EMR68696.1; -; Genomic_DNA.
DR   RefSeq; XP_007792220.1; XM_007794029.1.
DR   AlphaFoldDB; M7TFI1; -.
DR   STRING; 1287681.M7TFI1; -.
DR   KEGG; ela:UCREL1_4298; -.
DR   eggNOG; KOG1161; Eukaryota.
DR   eggNOG; KOG4580; Eukaryota.
DR   HOGENOM; CLU_009308_2_0_1; -.
DR   OMA; AAWGWYM; -.
DR   OrthoDB; 11387at2759; -.
DR   Proteomes; UP000012174; Unassembled WGS sequence.
DR   GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR   CDD; cd14480; SPX_VTC2_like; 1.
DR   Gene3D; 3.20.100.30; VTC, catalytic tunnel domain; 1.
DR   InterPro; IPR003807; DUF202.
DR   InterPro; IPR004331; SPX_dom.
DR   InterPro; IPR018966; VTC_domain.
DR   InterPro; IPR042267; VTC_sf.
DR   PANTHER; PTHR46140; VACUOLAR TRANSPORTER CHAPERONE 1-RELATED; 1.
DR   PANTHER; PTHR46140:SF2; VACUOLAR TRANSPORTER CHAPERONE 2-RELATED; 1.
DR   Pfam; PF02656; DUF202; 1.
DR   Pfam; PF09359; VTC; 1.
DR   PROSITE; PS51382; SPX; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000012174};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Vacuole {ECO:0000256|ARBA:ARBA00022554}.
FT   TRANSMEM        706..728
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        748..770
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          1..177
FT                   /note="SPX"
FT                   /evidence="ECO:0000259|PROSITE:PS51382"
FT   REGION          83..119
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          530..551
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          563..618
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          121..148
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        94..117
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        530..546
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   794 AA;  91803 MW;  2095A4B175DC0D75 CRC64;
     MRFGKTLRES IYSPWKEQYM DYSKLKTVLR VDKREDEDVP WTVEDENRFC DEIFNVQLEK
     VAQFQRKTAT NLQERAEAAF QKLKEFAPTN NKGDDGPVDE DSKKPKDSAD DEDDSQGQIK
     TQIATARLKE LRAELDSITN ELRELKRYCS INYTGFLKIV KKHDRKRGDL YKVRPMMRVS
     LSEQGFNSEQ EYSPLIKKLS LMYYIVNARL DEGEQQQQPL DLEQHEEVRH GERYTAHKFW
     VHPDNLLEVK TAILRHLPAV LYQQQDAKEL DGNEDLPTTS IYFDNKRFEL YSRKVDQQVD
     AASMRLRWYG QLNSRPDIVL EQKIIHENGT SEERRFNIKD KYIKQFIDGG YKMEKSIQKM
     ERQGQTPEAI ETFKSTVEEI QTFIKGNKLE PVLRANYTRT AFQKPDDRIR ILIDTDIAFI
     REDTLDPDRP CRDPQEWHRR DIDGSNMAYP FTHMNQSEVS RFPYALLEIK LKEDGVRKRP
     RWIEDLMGSH LLYAAPRFSK FIHGVASLFE DYVNNLPFWL SDLETDIRKD PQRAHDEEEQ
     RRAQRAEDAQ VVGSFLGTGA KTGSYKPISS SPLGKSHLSD RAAADAMAAS TSRAPDLGLD
     TEQDDTRDDN EENAEQERRG YGAISSVLPG FSLARYTRAR RQRVQQQQLP EGVTKPETWI
     KNAGPLQIEP KVWLANERTF LKWQHICILL GSLAVSLYTA AGEHNFLAEC MGVAYVAIAA
     LAGTWGYYML HVRRNMIMER SGRDFDNVLG PLFISVAMMV ALVLNFVFAY RNAFSKPDGD
     QMLNATESAF VGEL
//