ID M7TG99_EUTLA Unreviewed; 600 AA.
AC M7TG99;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE RecName: Full=Amine oxidase {ECO:0000256|RuleBase:RU000672};
DE EC=1.4.3.- {ECO:0000256|RuleBase:RU000672};
GN ORFNames=UCREL1_7276 {ECO:0000313|EMBL:EMR65735.1};
OS Eutypa lata (strain UCR-EL1) (Grapevine dieback disease fungus) (Eutypa
OS armeniacae).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Xylariomycetidae; Xylariales; Diatrypaceae; Eutypa.
OX NCBI_TaxID=1287681 {ECO:0000313|EMBL:EMR65735.1, ECO:0000313|Proteomes:UP000012174};
RN [1] {ECO:0000313|Proteomes:UP000012174}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UCR-EL1 {ECO:0000313|Proteomes:UP000012174};
RX PubMed=23723393; DOI=10.1128/genomeA.00228-13;
RA Blanco-Ulate B., Rolshausen P.E., Cantu D.;
RT "Draft genome sequence of the grapevine dieback fungus Eutypa lata UCR-
RT EL1.";
RL Genome Announc. 1:E0022813-E0022813(2013).
CC -!- COFACTOR:
CC Name=Cu cation; Xref=ChEBI:CHEBI:23378;
CC Evidence={ECO:0000256|RuleBase:RU000672};
CC Note=Contains 1 topaquinone per subunit.
CC {ECO:0000256|RuleBase:RU000672};
CC -!- PTM: Topaquinone (TPQ) is generated by copper-dependent autoxidation of
CC a specific tyrosyl residue. {ECO:0000256|RuleBase:RU000672}.
CC -!- SIMILARITY: Belongs to the copper/topaquinone oxidase family.
CC {ECO:0000256|ARBA:ARBA00007983, ECO:0000256|RuleBase:RU000672}.
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DR EMBL; KB706796; EMR65735.1; -; Genomic_DNA.
DR RefSeq; XP_007795164.1; XM_007796973.1.
DR AlphaFoldDB; M7TG99; -.
DR STRING; 1287681.M7TG99; -.
DR KEGG; ela:UCREL1_7276; -.
DR eggNOG; KOG1186; Eukaryota.
DR HOGENOM; CLU_011500_3_1_1; -.
DR OMA; HRDRELY; -.
DR OrthoDB; 34972at2759; -.
DR Proteomes; UP000012174; Unassembled WGS sequence.
DR GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR GO; GO:0008131; F:primary amine oxidase activity; IEA:InterPro.
DR GO; GO:0048038; F:quinone binding; IEA:InterPro.
DR GO; GO:0009308; P:amine metabolic process; IEA:UniProtKB-UniRule.
DR Gene3D; 3.10.450.40; -; 2.
DR Gene3D; 2.70.98.20; Copper amine oxidase, catalytic domain; 1.
DR InterPro; IPR000269; Cu_amine_oxidase.
DR InterPro; IPR015798; Cu_amine_oxidase_C.
DR InterPro; IPR036460; Cu_amine_oxidase_C_sf.
DR InterPro; IPR016182; Cu_amine_oxidase_N-reg.
DR InterPro; IPR015800; Cu_amine_oxidase_N2.
DR InterPro; IPR015802; Cu_amine_oxidase_N3.
DR PANTHER; PTHR10638:SF33; AMINE OXIDASE; 1.
DR PANTHER; PTHR10638; COPPER AMINE OXIDASE; 1.
DR Pfam; PF01179; Cu_amine_oxid; 1.
DR Pfam; PF02727; Cu_amine_oxidN2; 1.
DR Pfam; PF02728; Cu_amine_oxidN3; 1.
DR SUPFAM; SSF49998; Amine oxidase catalytic domain; 1.
DR SUPFAM; SSF54416; Amine oxidase N-terminal region; 2.
PE 3: Inferred from homology;
KW Copper {ECO:0000256|ARBA:ARBA00023008, ECO:0000256|RuleBase:RU000672};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU000672};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU000672};
KW Reference proteome {ECO:0000313|Proteomes:UP000012174};
KW TPQ {ECO:0000256|ARBA:ARBA00022772, ECO:0000256|RuleBase:RU000672}.
FT DOMAIN 4..76
FT /note="Copper amine oxidase N2-terminal"
FT /evidence="ECO:0000259|Pfam:PF02727"
FT DOMAIN 103..193
FT /note="Copper amine oxidase N3-terminal"
FT /evidence="ECO:0000259|Pfam:PF02728"
FT DOMAIN 231..600
FT /note="Copper amine oxidase catalytic"
FT /evidence="ECO:0000259|Pfam:PF01179"
SQ SEQUENCE 600 AA; 67507 MW; 54DE971EC8C124D4 CRC64;
MAPHPLADLT TNEIGQARDL VQAKHPRTLL SFKAITLEEP TKELMLEYLE AEHAGKSATC
PNRIAYCAYY FRGTQKLLTA EVNLTTGQTQ VVDHEGDGVH GNVDFAEVLE VEKAVMECPE
VRAEIDKLML PDHLEVIPEP WGFGSDGVDD LSRYFQVYMF IREKGKLDSN HYARPLAFSP
IFDPTTMKLV RIQHISTGAG HDVNEQGVYK ETPPNEYIPS EVQLRTDLEP LHVVQPNGPS
FEITKDRVVK WQKWQIRVGF NYREGLVLRD IRYDGRPLFY RVSLSEMCVP YGDPRSPYHR
KMAFDLGDVG AGMVCNNLKL GCDCLGSIAY LDGLVCDRDG HPVVKENAIC IHEQDNGIGW
KHTNYRTDTE GAADMIKRYI LMFIFNQAGE MEYQVRATGI LSTSAINEGV TVDFGTVVHP
GVLAAHHQHI LSLRIDPIIG SYLYGNTVVQ QEAEAMPMDE YNPHGNGYRV VKTDIVTEGG
HDLDWAKSRV FSVKNPHLLN PINGLPISYK LMFPPVPPLL SHPSSFNAKR AEFGDHHLYV
TKYRPDELFS GGKFTNQSRG DTGIKSWIAK NEASTVDQDV VLWVQFGLNH VPRIEDFPVM
//
