ID   M7TGP2_BOTF1            Unreviewed;       355 AA.
AC   M7TGP2;
DT   29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2013, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   SubName: Full=Putative nadp-dependent leukotriene b4 12-hydroxydehydrogenase protein {ECO:0000313|EMBL:EMR80530.1};
GN   ORFNames=BcDW1_10911 {ECO:0000313|EMBL:EMR80530.1};
OS   Botryotinia fuckeliana (strain BcDW1) (Noble rot fungus) (Botrytis
OS   cinerea).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Sclerotiniaceae; Botrytis.
OX   NCBI_TaxID=1290391 {ECO:0000313|EMBL:EMR80530.1, ECO:0000313|Proteomes:UP000012045};
RN   [1] {ECO:0000313|Proteomes:UP000012045}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BcDW1 {ECO:0000313|Proteomes:UP000012045};
RX   PubMed=23704180; DOI=10.1128/genomea.00252-13;
RA   Blanco-Ulate B., Allen G., Powell A.L., Cantu D.;
RT   "Draft genome sequence of Botrytis cinerea BcDW1, inoculum for noble rot of
RT   grape berries.";
RL   Genome Announc. 1:E0025213-E0025213(2013).
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DR   EMBL; KB708120; EMR80530.1; -; Genomic_DNA.
DR   AlphaFoldDB; M7TGP2; -.
DR   STRING; 1290391.M7TGP2; -.
DR   HOGENOM; CLU_026673_29_1_1; -.
DR   Proteomes; UP000012045; Unassembled WGS sequence.
DR   GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   CDD; cd05288; PGDH; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR041694; ADH_N_2.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR045010; MDR_fam.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   PANTHER; PTHR43205; PROSTAGLANDIN REDUCTASE; 1.
DR   PANTHER; PTHR43205:SF7; PROSTAGLANDIN REDUCTASE 1; 1.
DR   Pfam; PF16884; ADH_N_2; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          96..344
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   355 AA;  38362 MW;  1B22D086CB20A916 CRC64;
     MVQNKGLIFK QVPQGVPVAG KDLVVETREF DLDQAPPAGG ITTKNFYASF DPYQRGRMRA
     AEAKSYSPAF PLGQPINNST IAKVIKSDNP KFQPGDLLTG FIWTEEYSAL PKQLADGATK
     IENPHKLDVK HFLGALGMPG LTAYSSFYEI GKPVKGETIF ISSASGAVGA LVGQLAKHEG
     LTVIGSVGSD DKLDYIINEL KFDGGFNYKT EKSADALKRL APNGIDIYYE NVGGEQLEAA
     INAMKDYGRI VACGMISEYS KPEADRYPIK NLMNIVAKRI TMRGFIVSDA NMGPLHVKAR
     DENVAKWLAD GSFKASLSVT EGIDNGPEGL IGMLAGKNFG KAVLKIADFE VSFVH
//