ID M7U2A0_BOTF1 Unreviewed; 857 AA.
AC M7U2A0;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Putative ubiquitin ligase subunit protein {ECO:0000313|EMBL:EMR80723.1};
GN ORFNames=BcDW1_10686 {ECO:0000313|EMBL:EMR80723.1};
OS Botryotinia fuckeliana (strain BcDW1) (Noble rot fungus) (Botrytis
OS cinerea).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Sclerotiniaceae; Botrytis.
OX NCBI_TaxID=1290391 {ECO:0000313|EMBL:EMR80723.1, ECO:0000313|Proteomes:UP000012045};
RN [1] {ECO:0000313|Proteomes:UP000012045}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BcDW1 {ECO:0000313|Proteomes:UP000012045};
RX PubMed=23704180; DOI=10.1128/genomea.00252-13;
RA Blanco-Ulate B., Allen G., Powell A.L., Cantu D.;
RT "Draft genome sequence of Botrytis cinerea BcDW1, inoculum for noble rot of
RT grape berries.";
RL Genome Announc. 1:E0025213-E0025213(2013).
CC -!- SIMILARITY: Belongs to the cullin family.
CC {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC ECO:0000256|RuleBase:RU003829}.
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DR EMBL; KB708106; EMR80723.1; -; Genomic_DNA.
DR AlphaFoldDB; M7U2A0; -.
DR STRING; 1290391.M7U2A0; -.
DR HOGENOM; CLU_004747_7_0_1; -.
DR Proteomes; UP000012045; Unassembled WGS sequence.
DR GO; GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR045093; Cullin.
DR InterPro; IPR016157; Cullin_CS.
DR InterPro; IPR016158; Cullin_homology.
DR InterPro; IPR036317; Cullin_homology_sf.
DR InterPro; IPR001373; Cullin_N.
DR InterPro; IPR019559; Cullin_neddylation_domain.
DR InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11932; CULLIN; 1.
DR PANTHER; PTHR11932:SF126; CULLIN 4, ISOFORM A; 1.
DR Pfam; PF00888; Cullin; 1.
DR Pfam; PF10557; Cullin_Nedd8; 1.
DR SMART; SM00182; CULLIN; 1.
DR SMART; SM00884; Cullin_Nedd8; 1.
DR SUPFAM; SSF75632; Cullin homology domain; 1.
DR SUPFAM; SSF74788; Cullin repeat-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS01256; CULLIN_1; 1.
DR PROSITE; PS50069; CULLIN_2; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000313|EMBL:EMR80723.1};
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT DOMAIN 476..730
FT /note="Cullin family profile"
FT /evidence="ECO:0000259|PROSITE:PS50069"
FT REGION 1..86
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 502..523
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 29..44
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 51..72
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 504..523
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 857 AA; 97257 MW; EA7968659EBB5267 CRC64;
MWPSHDRAVD LSSTSSSSPA KRKHRDPQGP NPSSANTPPG TSKVDCHSSK KLRPISSSTS
PGLRSNMNKT MGFSRPGVVD LTRPSNFQPH TGAKRLVIKN LRISSPSDGE QYFQKTWDEL
DGALASVFSN QQPVTPLEVL CRGVESICRR GKDKADQLYR HLEQHCHTHI KDGLLPDILR
KGDSNSVETL RAVETVWGIW RTQLILLRSI FSYLDRSYLL NSKTLPQLED MGIRQFRQIV
FFKGKEISKT GAQTILGICE LVKYDRKSLD LFDSALLRAS IATIHILGIY TSLFEERFQD
ISSAYLENFA SERSSSPLRE YISSCDDLLR RESLRCDTYN FDSTTKKTLL DNAHDILVLK
RADVLLETVA VSKLLDDKEM ASLKSLYQLL RLSDIQAQLK KPFAYYIKSV GSSIAMDKER
SDEMVVRLLE LKRSLDTVIR DAFNKDGTFT FCLRDAFGQF INDRQVAKAW GTDTSKVGEM
IAKYMDGLLR GGLKAVPRSL VSDATDRNEA EKNGQASTGD EDAELDRQLE QGLELFRFIE
GKDVFEAFYK KDLARRLLMA RSASQDAERN MLAKLRGECG NSFTHNLEQM FKDQDISRDE
MISYKQSLSN TSKTTLDLQV SVLSSAAWPT YPDIEVNLPA EVARHIEKYD RHYKHKHSGR
RLTWKHSLAH SVVKATFKKS VKELLVSGFQ AIVLVLFNDL EDGGHLSYKD ISKATGLVDV
ELKRTLQSLA CAKIRPLAKY PKGRDINDTD TFTINLNFSD PKYRIKINQI QLKETKEENK
ETHERVIQDR SFETQAAIVR IMKSRKTMTH QNLVAEVINQ TKGRGAVEPA EIKKHIEKLI
EKDYIEREDG GHYTYLA
//
