ID   M7U4P7_BOTF1            Unreviewed;      1036 AA.
AC   M7U4P7;
DT   29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2013, sequence version 1.
DT   24-JAN-2024, entry version 29.
DE   SubName: Full=Putative px domain-containing protein {ECO:0000313|EMBL:EMR88609.1};
GN   ORFNames=BcDW1_2737 {ECO:0000313|EMBL:EMR88609.1};
OS   Botryotinia fuckeliana (strain BcDW1) (Noble rot fungus) (Botrytis
OS   cinerea).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Sclerotiniaceae; Botrytis.
OX   NCBI_TaxID=1290391 {ECO:0000313|EMBL:EMR88609.1, ECO:0000313|Proteomes:UP000012045};
RN   [1] {ECO:0000313|Proteomes:UP000012045}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BcDW1 {ECO:0000313|Proteomes:UP000012045};
RX   PubMed=23704180; DOI=10.1128/genomea.00252-13;
RA   Blanco-Ulate B., Allen G., Powell A.L., Cantu D.;
RT   "Draft genome sequence of Botrytis cinerea BcDW1, inoculum for noble rot of
RT   grape berries.";
RL   Genome Announc. 1:E0025213-E0025213(2013).
CC   -!- SIMILARITY: Belongs to the sorting nexin family.
CC       {ECO:0000256|ARBA:ARBA00010883}.
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DR   EMBL; KB707784; EMR88609.1; -; Genomic_DNA.
DR   AlphaFoldDB; M7U4P7; -.
DR   STRING; 1290391.M7U4P7; -.
DR   HOGENOM; CLU_007315_0_0_1; -.
DR   Proteomes; UP000012045; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   CDD; cd06093; PX_domain; 1.
DR   Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR   InterPro; IPR003114; Phox_assoc.
DR   InterPro; IPR001683; PX_dom.
DR   InterPro; IPR036871; PX_dom_sf.
DR   InterPro; IPR013937; Sorting_nexin_C.
DR   PANTHER; PTHR22775:SF47; MEIOTICALLY UP-REGULATED GENE 122 PROTEIN; 1.
DR   PANTHER; PTHR22775; SORTING NEXIN; 1.
DR   Pfam; PF08628; Nexin_C; 1.
DR   Pfam; PF00787; PX; 1.
DR   Pfam; PF02194; PXA; 1.
DR   SMART; SM00313; PXA; 1.
DR   SUPFAM; SSF64268; PX domain; 1.
DR   PROSITE; PS51207; PXA; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        34..65
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          104..286
FT                   /note="PXA"
FT                   /evidence="ECO:0000259|PROSITE:PS51207"
FT   REGION          374..441
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          643..872
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        379..441
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        643..698
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        743..770
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        789..804
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        822..862
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1036 AA;  113127 MW;  27666504F2A5CE2A CRC64;
     MDSTNESKVA EVATDDHITT RLLRFISTAS TEQLLLAALA LAFGTYIIFD GLFLLLLGAL
     GGVVLHTIFT EKSALAVREE AVKPKDIQYE LIEAGAGINF ESFRPKTATA LNDLVEAVIR
     DYVKHWYSPI LPNDEAFPIA AKSTLTRFIL SMSQRLSRKR PADTFLDFLT NSSSITIVFL
     NELANATSAT PGTSRPVGEM VTAYLSANPD SSLANIMNER QQKIKFTMAA DDLLRSFLEK
     SVYESGPARI FLREILAGVV LEMTLKSCSK PEFINGWIVH LLEDGEPGLG QAIDEAMDRR
     NIHDPFSDID GNVGNISIAR SPKKQGHQRR ITDEDATNEA MAEAKRLSML IAAEDAKKLA
     QIDDFKDEEN KVLDDQNAKE NIQPESVLLS PTTGIPPHTP ITDSRSSLSG SDANGRSPMS
     PDSKQAISPT TPQTTSSFTS FDQIVPPTPA ALYSNETSPQ RSKPAPLTLH NANIIIYDDS
     IASDKARIKS KPTMDYMVQI EPRSSIYPGW MIVRRYSDFE TLHEVLGRIA KVSGANIFIE
     KHQDLPSWKT LTKPLLRGEL EQYLKDALTH QPLAETEGMK RFLEKDQGTM PAAATKVGFN
     WPTSSLENMG KGMFDTLKSA PKGAAAGVTG VFSNIGSLAQ KRASQSSLQS QNRISTPAPS
     RVDSMASQNS LQSQNRNSTP ALSRVDSMAS SNGSSFEQKR GRLSEESMKA ASVISHPGKT
     ASLGRRLSRG SIPGDEEEFG IRTRGSSVSS HMSTAYSPSN SREPSQTPST SKLHLPPPPT
     EMPDDYTIST DRPLNNSVLE NENKGAITAP NEKKPTPIDK SLHQDVLSND NSIAPTPENE
     KRPTLTLKSL NQDMPGSDNN KTPLLSKEKK TAPLNEEETK VAIELLFAII TELYTLSSAW
     NFRRTLLTAA KTFLLRPGNP SLSSIQGLLQ ESVISAYTSD VGIASSIQKL RENGLPTEAE
     LKAWPEEMTA ENKEKLKTKA RKLLLERGMP IALMGVMGQA ATGEALGKVF DALQREDIAR
     GLVFGLLLQG IKAITQ
//