ID M7U6L5_BOTF1 Unreviewed; 232 AA.
AC M7U6L5;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Voltage-gated hydrogen channel 1 {ECO:0000256|ARBA:ARBA00015897};
DE AltName: Full=Hydrogen voltage-gated channel 1 {ECO:0000256|ARBA:ARBA00031989};
GN ORFNames=BcDW1_2101 {ECO:0000313|EMBL:EMR89230.1};
OS Botryotinia fuckeliana (strain BcDW1) (Noble rot fungus) (Botrytis
OS cinerea).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Sclerotiniaceae; Botrytis.
OX NCBI_TaxID=1290391 {ECO:0000313|EMBL:EMR89230.1, ECO:0000313|Proteomes:UP000012045};
RN [1] {ECO:0000313|Proteomes:UP000012045}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BcDW1 {ECO:0000313|Proteomes:UP000012045};
RX PubMed=23704180; DOI=10.1128/genomea.00252-13;
RA Blanco-Ulate B., Allen G., Powell A.L., Cantu D.;
RT "Draft genome sequence of Botrytis cinerea BcDW1, inoculum for noble rot of
RT grape berries.";
RL Genome Announc. 1:E0025213-E0025213(2013).
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the hydrogen channel family.
CC {ECO:0000256|ARBA:ARBA00008437}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KB707755; EMR89230.1; -; Genomic_DNA.
DR AlphaFoldDB; M7U6L5; -.
DR STRING; 1290391.M7U6L5; -.
DR HOGENOM; CLU_076372_1_0_1; -.
DR Proteomes; UP000012045; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030171; F:voltage-gated proton channel activity; IEA:InterPro.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR031846; Hvcn1.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR46480; F20B24.22; 1.
DR PANTHER; PTHR46480:SF1; VOLTAGE-GATED HYDROGEN CHANNEL 1; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR SUPFAM; SSF160459; BLRF2-like; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 64..86
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 106..129
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 141..160
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 66..180
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT REGION 211..232
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 232 AA; 26251 MW; 1A0BB57247346CF6 CRC64;
MSRRNSDISE HAPLIRASSQ PISIASGPSY HHVPHPSFSR KLANSYRKSQ TSAKSFLSSR
AQHYTVLLLV ACDLISIISD IIINLYQCDN DKEGKTDPIW NEVRDGLGIA GLIFSCLFMA
ELIVSVWAFG LSYFRSKFHC FDATVIVAGF VVDVLLHGVL EEVASLVIIL RLWRFFKIIE
EFSVGAEEQM DVLEERIEQL EMENRELKRQ LRKRKDGDED LENGEGGSES EN
//
