ID M7UAW0_BOTF1 Unreviewed; 2557 AA.
AC M7UAW0;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Putative gtpase-activator protein for ras-like gtpase protein {ECO:0000313|EMBL:EMR83758.1};
GN ORFNames=BcDW1_7600 {ECO:0000313|EMBL:EMR83758.1};
OS Botryotinia fuckeliana (strain BcDW1) (Noble rot fungus) (Botrytis
OS cinerea).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Sclerotiniaceae; Botrytis.
OX NCBI_TaxID=1290391 {ECO:0000313|EMBL:EMR83758.1, ECO:0000313|Proteomes:UP000012045};
RN [1] {ECO:0000313|Proteomes:UP000012045}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BcDW1 {ECO:0000313|Proteomes:UP000012045};
RX PubMed=23704180; DOI=10.1128/genomea.00252-13;
RA Blanco-Ulate B., Allen G., Powell A.L., Cantu D.;
RT "Draft genome sequence of Botrytis cinerea BcDW1, inoculum for noble rot of
RT grape berries.";
RL Genome Announc. 1:E0025213-E0025213(2013).
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DR EMBL; KB707981; EMR83758.1; -; Genomic_DNA.
DR STRING; 1290391.M7UAW0; -.
DR HOGENOM; CLU_000249_0_2_1; -.
DR Proteomes; UP000012045; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR CDD; cd05392; RasGAP_Neurofibromin_like; 1.
DR Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR001251; CRAL-TRIO_dom.
DR InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR039360; Ras_GTPase.
DR InterPro; IPR023152; RasGAP_CS.
DR InterPro; IPR001936; RasGAP_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR PANTHER; PTHR10194:SF150; INHIBITORY REGULATOR PROTEIN IRA1-RELATED; 1.
DR PANTHER; PTHR10194; RAS GTPASE-ACTIVATING PROTEINS; 1.
DR Pfam; PF13716; CRAL_TRIO_2; 1.
DR Pfam; PF00616; RasGAP; 1.
DR SMART; SM00323; RasGAP; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS00509; RAS_GTPASE_ACTIV_1; 1.
DR PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT DOMAIN 1184..1385
FT /note="Ras-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50018"
FT REGION 88..128
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 88..108
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 109..128
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2557 AA; 285391 MW; 9273D0CB7AAB0C9E CRC64;
MLPSLPHKTG ADAHHLNRDE IALLSRTTLV DISKPSIAVV TEALVQLLED LARPYKTISA
HPLHVLHSEF YVLELLAECC TTHWESINDS ENTSDRENAP SQGFRSNDSI KPEGRRASRN
KLLARDNPPE ALDDDLAKRI IDVIKLFSNP IPDGYVLPAF NILDDVLGTS PASQSPGLDP
LNGTNGQQNT TEAAILIQEH SESTEACIRK VVEFVSFSNW PRTLEYLRGS LRGLLAAQSS
NGNQAQNGAV VDDEALVTVR LIPSFWVDSR KLGVVIQELC GSFLHLRKAF QTIVAIVVPQ
LITRWLERNP EEFIQLHTMH KRLDGGAETL FDMTNTMIDA GRRKTLLFPF QTSLLFLLPD
VFEVASNMRD IKSSSISKKV SFLEMLRKTL RNRNEAAIYC LTSVLRVARH FPLDSDSALL
SYALDVQEEV REAVFRRYTV GAENTSIDSG LMTAAFVSLA HLNFRTCVDS LAPFCLAPNT
SSDFKLAVIR ACTHFAKQSN ASDYNPLFIK LSEFIRTYMK GTTFRFRDSY PIEHVTMNRQ
TKFSSSGELV YSMLVFLDVY PMALFVGMDL GSRHNDTAFE DVYAALMAFL TSEDEKIRIL
TSEVCRSSLT EATMSAWQKK DYKFTNAAKF HFWESTSIIL SSISSKIINQ TVEEHNALSF
VHSYLQARLD LLKKIKDLTE LEEDISERLA AYSMMETTFL VTACSPDIAI CQLVASSVCL
FAEEIRLVES APNFAKHSLA SARNMEVYQE LASKDFRFTG IVAFQKRTRG LLRRMQYPTA
GIINAWETIF DRWVRLSKQL IARPEIVDER SMGEWRNCSG FLASLGGICV VGQSLLSASD
DQVLTSLRWI DKIPAESYDD ETLLSRYMRQ SVQLLASNNI RIREGTRDAL SSDLAKPLHM
PLFEALQTEL DILFDSPRSN AIPVDSRIIF AEQAAALLKS IVEKLGSPAE LGTGMSVDIG
ALALNFAKFL NSSADGASAL RVKIKICQLC ETLTQKKELL NLRHDVRIRN QLLEVIFGWI
ARPGTPNADT GVHLVGTRLD EIFRLQKDLD RASLKALAEL TYRLPLQPAE GQSDADTSDL
KSQMFHTYFN RFLSLLNYET VDIGRNEVRL TSAVSDDSMS SPELAISALS NLLSANIDVG
LKHSLGIGYH EDIEVRTAFV KVLCNILIQG TEFNNLSDAA VNQKYDELLE LLINDMTLTI
ALCDACPSTE VDEMTISLLN IFDSRENEAE LLRRNCVATK LLSVYAKWKG AAYLKATLQK
VLERLVLTSK DLDLELDPAR TTSPEELQKN ALQLRVVTKV FIDDICNSAS RIPVSFRKIC
NIISSCVMRR FPDAKFTAVG AFIFLRFFCP AIVAPDAEGL IASPPSKEMR RGLLLIAKVV
QNLANNVLFG AKEPYMYPLN DFLTQNIYRV TTFLREISAP PNVRETLAES ESFDFGSCVA
LHRFLYDHWD HVRQKLVLRE RQLSLRSPID GTKSHTPVLD ALRTLISNLG PPPMDVSWNR
PAISHNTPPS YSRFQHFMLR NAGRSSEAVV SNRAVYDGGE SKDGLSMICI ILRNIDTDGT
DYDLLLYVYL KIASRMWHKP FGILIDATCY NGQNEPADAL FRRLDLLTPT ELSKQLSRVY
VYNMNSAFRK CFRRILRLSA KSENSAFHPK NVDYHLIGSL QDLQSHFHLT QLHLPKETIS
VVTDTRYVFQ PIIRLSKTKG KVEVIIKIGS QFVQVTTTKK QEVVPGLRLH ATVNDIFRLS
EVDEAPTSIQ TEDDSAFGLR TDNGKIVMYF TSPRKGDILQ SIRSAKNRHG KELRTLKSFE
RLVRPQDVPG TLLNIALTNM ASPDAVLRLA AYNLLCALCR AFKFAADSKF MSTKELCVPL
NPSQFIIDIS AQLARSEPQL TGDFLNEFFV GWESFPYSQR PLSLAYMAPW LPSLRTHLIP
NEPDSDKGRD KVAVIFRKLI EVAISDVVLS TTLEQSIWPV ICQDEVYIDI FLEEILKPAL
NFGIDDERTE ILGSILASLG TVTIRGKLIS RLRKALNRTS LRPTRHLHEN TVWGEICVLL
RLTLSVSFDS GVQSQLYLPE VFHLVTMLAN TGSSDLRLIV HRLLVNTIHA MCTTFVLEES
KLAKLKLLLS SISEPRQESL FSIASRDGAS LPSSQDSGPS ALLATESLAN LLSDISIVAA
PTVDLSNTWR ARWMSLVAST AFQSNPAIQP RAFTVMGCLA REDVDDDLLY QVLVALRSSI
GRYMDDGDSE MMVAIVTALT KMMDKLPSAS RYGTQLFWLA LSLVRLVPIG LFNCAAMFLD
AVLLNIGASG ELGNGRMIQT LLLGRVPLDE AAIQLDEIYG IHFTAENFHF AVSACMVKGM
TDSLTRSTAM RVISTFLDTT TTNAPEGISF PQDVSCMPYL GLLLGRALNP EDAGHSLWMA
TATQGDLTPH TEADMESIMQ IAGLNEKELL LTCAIGLVDF HYLDDTIQNS AFQWLNKLAI
SSSNVMLRLA GPITSILDDV LMSCQNSITL ESAHQLLRTI TSNPQFSAAM RDADVLDRVL
GSIGFGGLWK NSTYQGHHEV ARECTTLTDR LIELIIA
//
