ID M7UBB5_BOTF1 Unreviewed; 629 AA.
AC M7UBB5;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=DNA-directed RNA polymerase III subunit RPC3 {ECO:0000256|RuleBase:RU367076};
DE Short=RNA polymerase III subunit C3 {ECO:0000256|RuleBase:RU367076};
GN ORFNames=BcDW1_7457 {ECO:0000313|EMBL:EMR83933.1};
OS Botryotinia fuckeliana (strain BcDW1) (Noble rot fungus) (Botrytis
OS cinerea).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Sclerotiniaceae; Botrytis.
OX NCBI_TaxID=1290391 {ECO:0000313|EMBL:EMR83933.1, ECO:0000313|Proteomes:UP000012045};
RN [1] {ECO:0000313|Proteomes:UP000012045}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BcDW1 {ECO:0000313|Proteomes:UP000012045};
RX PubMed=23704180; DOI=10.1128/genomea.00252-13;
RA Blanco-Ulate B., Allen G., Powell A.L., Cantu D.;
RT "Draft genome sequence of Botrytis cinerea BcDW1, inoculum for noble rot of
RT grape berries.";
RL Genome Announc. 1:E0025213-E0025213(2013).
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC Specific core component of RNA polymerase III which synthesizes small
CC RNAs, such as 5S rRNA and tRNAs. {ECO:0000256|ARBA:ARBA00025127,
CC ECO:0000256|RuleBase:RU367076}.
CC -!- SUBUNIT: Component of the RNA polymerase III (Pol III) complex
CC consisting of 17 subunits. {ECO:0000256|ARBA:ARBA00011206,
CC ECO:0000256|RuleBase:RU367076}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU367076}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC {ECO:0000256|ARBA:ARBA00006835, ECO:0000256|RuleBase:RU367076}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KB707975; EMR83933.1; -; Genomic_DNA.
DR AlphaFoldDB; M7UBB5; -.
DR STRING; 1290391.M7UBB5; -.
DR HOGENOM; CLU_023294_0_0_1; -.
DR Proteomes; UP000012045; Unassembled WGS sequence.
DR GO; GO:0005666; C:RNA polymerase III complex; IEA:UniProtKB-UniRule.
DR GO; GO:0003697; F:single-stranded DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR008806; RNA_pol_III_Rpc82_C.
DR InterPro; IPR039748; RPC3.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR12949:SF0; DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC3; 1.
DR PANTHER; PTHR12949; RNA POLYMERASE III DNA DIRECTED -RELATED; 1.
DR Pfam; PF05645; RNA_pol_Rpc82; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000256|RuleBase:RU367076}; Nucleus {ECO:0000256|RuleBase:RU367076};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU367076}.
FT DOMAIN 124..462
FT /note="RNA polymerase III Rpc82 C -terminal"
FT /evidence="ECO:0000259|Pfam:PF05645"
FT REGION 93..116
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 338..418
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 94..116
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 340..357
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 365..387
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 629 AA; 71064 MW; AD4A600597F215BB CRC64;
MNALKRHTQL TTRQLKLGLT VLVRQNLVYH NSEGSDTHYE ANIDAAYALV RSGKILEIAE
ERFGSVAAEI MGQLVLLGHA KISDIIAELN KNHEPHANGN SNETNGATNG NGVHSYPSGQ
LNHTLIQLLE EGFIQPVGQN MFRSPTDSYN AVEKALLQDS YGGATRGTKQ KDELRMRIRG
QLQELRAQVP NWKPVGYNRS STNGHTNDIA SKRRRLSHSG GATNGYDFGD DESSKLDGNL
VLRINHEKCT VFMRNRRLVE LANSRIGVTT SYIYAELLRL MAEQIPRCRP DPRIDDAVDD
ADGPSIIITT QELTDALSKT INVSTGIGKA TSQKIDTSRL DKLQNGRKRK AQDEAEVEGV
ASSDEESEDD HKPFTNGNGH AMDVDEDDPF SDQPGANTSK RAVTFKDRDR TPPPTESRQA
RMMHVMSHLQ LLAADDCQLL RKCGARQMGE WTVDFERVID RLRESELDSI IYENFGQIGH
RLVRVMRKMG KLEEKHIAKL ALIKQQDSRT TLVNMQMHGM VDIQEVPRDT GRMIVRTIHL
WFCDEDRVTS LLLDRTYKAM SRCLQRLDVE KRRKANIIAL SERTDVQGQE EAFLRPEQMN
QLREIRAKEE DLLGQICRLD ELVGIFQDY
//
