ID M7US95_BOTF1 Unreviewed; 663 AA.
AC M7US95;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE SubName: Full=Putative vhs domain-containing protein {ECO:0000313|EMBL:EMR86647.1};
GN ORFNames=BcDW1_4655 {ECO:0000313|EMBL:EMR86647.1};
OS Botryotinia fuckeliana (strain BcDW1) (Noble rot fungus) (Botrytis
OS cinerea).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Sclerotiniaceae; Botrytis.
OX NCBI_TaxID=1290391 {ECO:0000313|EMBL:EMR86647.1, ECO:0000313|Proteomes:UP000012045};
RN [1] {ECO:0000313|Proteomes:UP000012045}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BcDW1 {ECO:0000313|Proteomes:UP000012045};
RX PubMed=23704180; DOI=10.1128/genomea.00252-13;
RA Blanco-Ulate B., Allen G., Powell A.L., Cantu D.;
RT "Draft genome sequence of Botrytis cinerea BcDW1, inoculum for noble rot of
RT grape berries.";
RL Genome Announc. 1:E0025213-E0025213(2013).
CC -!- SUBUNIT: Component of the ESCRT-0 complex composed of HSE1 and VPS27.
CC {ECO:0000256|ARBA:ARBA00011446}.
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DR EMBL; KB707850; EMR86647.1; -; Genomic_DNA.
DR AlphaFoldDB; M7US95; -.
DR STRING; 1290391.M7US95; -.
DR HOGENOM; CLU_017092_0_0_1; -.
DR Proteomes; UP000012045; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0043130; F:ubiquitin binding; IEA:InterPro.
DR GO; GO:0016482; P:cytosolic transport; IEA:UniProt.
DR GO; GO:0016197; P:endosomal transport; IEA:UniProt.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0007034; P:vacuolar transport; IEA:UniProt.
DR CDD; cd14235; GAT_GGA_fungi; 1.
DR CDD; cd16998; VHS_GGA_fungi; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.58.160; -; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR Gene3D; 2.60.40.1230; -; 1.
DR InterPro; IPR008152; Clathrin_a/b/g-adaptin_app_Ig.
DR InterPro; IPR013041; Clathrin_app_Ig-like_sf.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR008153; GAE_dom.
DR InterPro; IPR004152; GAT_dom.
DR InterPro; IPR038425; GAT_sf.
DR InterPro; IPR002014; VHS_dom.
DR PANTHER; PTHR47180; ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA1-RELATED; 1.
DR PANTHER; PTHR47180:SF1; ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA1-RELATED; 1.
DR Pfam; PF02883; Alpha_adaptinC2; 1.
DR Pfam; PF03127; GAT; 1.
DR Pfam; PF00790; VHS; 1.
DR SMART; SM00809; Alpha_adaptinC2; 1.
DR SMART; SM00288; VHS; 1.
DR SUPFAM; SSF49348; Clathrin adaptor appendage domain; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF89009; GAT-like domain; 1.
DR PROSITE; PS50180; GAE; 1.
DR PROSITE; PS50909; GAT; 1.
DR PROSITE; PS50179; VHS; 1.
PE 4: Predicted;
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 32..168
FT /note="VHS"
FT /evidence="ECO:0000259|PROSITE:PS50179"
FT DOMAIN 195..322
FT /note="GAT"
FT /evidence="ECO:0000259|PROSITE:PS50909"
FT DOMAIN 543..661
FT /note="GAE"
FT /evidence="ECO:0000259|PROSITE:PS50180"
FT REGION 354..392
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 411..525
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 358..381
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 411..432
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 463..480
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 489..509
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 663 AA; 72401 MW; 7E22126013522FED CRC64;
MEAASARMAA RDRFSMMGDP GPSALQRYIQ QACSPENYEP NLAMNLEISD LINSKKGNAP
REAAIAIVNY INHRNPNVAI LALVLLDICV KNCGYPFHLQ ISTKEFLNEL VRRFPERPPI
RPSKVQMKIL EAIEEWRGTI CQTSRYKEDL GFIRDMHRLL SYKGYVFPEV RVEDAAVLNP
SDNLKSAEEM EEEEKAAQSA KLQELIRRGG PEDLQEANRL MKIMAGYDTR SKTDYRAKAA
EEVGKVQQKA RLLEERLEEF KPGDVMTEGD VYEELASALQ SAHPKIQKMC EEESDDHEAV
AKLLEINDSI HRTVERYKLM KKGDVDAASK IAKGTLGTST GVSKNSANEL SLIDFDGEPE
TNGSSSTSNA PASTSQPGDL ENDLLGLSMG DSSYSQEGGI SLGFGNNTNI PGPALMSSTT
ENSTARGPTP TRSPVPSNLP VKPDYSAFSA FGSQPPSKPV TPQPSLFQQQ QQQQQAAAAR
PPPSNIDPFA ALTSPSRQST PQQSGSIFDF ANPKPPVSHA ANAPAPVTDD DEWAFSSALP
EGLPSTNDLT ISNTNVKISL NASREPTTPD VITLSIAFSN NSNESISDLT FQAAVTKGYT
LRLQPQSGRR LNPHQESGIT QKIYLQGVEH GKGDQVKMRW KCSYKLGAQN SNEQGEIASL
GIS
//
