ID M7UUW3_BOTF1 Unreviewed; 2019 AA.
AC M7UUW3;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Putative helicase sen1 protein {ECO:0000313|EMBL:EMR90833.1};
GN ORFNames=BcDW1_537 {ECO:0000313|EMBL:EMR90833.1};
OS Botryotinia fuckeliana (strain BcDW1) (Noble rot fungus) (Botrytis
OS cinerea).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Sclerotiniaceae; Botrytis.
OX NCBI_TaxID=1290391 {ECO:0000313|EMBL:EMR90833.1, ECO:0000313|Proteomes:UP000012045};
RN [1] {ECO:0000313|Proteomes:UP000012045}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BcDW1 {ECO:0000313|Proteomes:UP000012045};
RX PubMed=23704180; DOI=10.1128/genomea.00252-13;
RA Blanco-Ulate B., Allen G., Powell A.L., Cantu D.;
RT "Draft genome sequence of Botrytis cinerea BcDW1, inoculum for noble rot of
RT grape berries.";
RL Genome Announc. 1:E0025213-E0025213(2013).
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DR EMBL; KB707685; EMR90833.1; -; Genomic_DNA.
DR STRING; 1290391.M7UUW3; -.
DR HOGENOM; CLU_000459_2_0_1; -.
DR Proteomes; UP000012045; Unassembled WGS sequence.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR CDD; cd18042; DEXXQc_SETX; 1.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR045055; DNA2/NAM7-like.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR024481; Helicase_Sen1_N.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047187; SF1_C_Upf1.
DR PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR PANTHER; PTHR10887:SF525; HELICASE SENATAXIN-RELATED; 1.
DR Pfam; PF13086; AAA_11; 1.
DR Pfam; PF13087; AAA_12; 1.
DR Pfam; PF12726; SEN1_N; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000313|EMBL:EMR90833.1};
KW Helicase {ECO:0000313|EMBL:EMR90833.1};
KW Hydrolase {ECO:0000313|EMBL:EMR90833.1};
KW Nucleotide-binding {ECO:0000313|EMBL:EMR90833.1}.
FT DOMAIN 92..821
FT /note="Helicase Sen1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12726"
FT DOMAIN 1320..1616
FT /note="DNA2/NAM7 helicase helicase"
FT /evidence="ECO:0000259|Pfam:PF13086"
FT DOMAIN 1623..1819
FT /note="DNA2/NAM7 helicase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13087"
FT REGION 965..997
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1015..1034
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1039..1061
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1874..2019
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 975..997
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1889..1919
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1920..1949
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2019 AA; 226996 MW; 112552FC622BF4D2 CRC64;
MPDEADIMDE LHGLHGELKS FPADAHWFCP KRNDEDYVDY SHPDDAEEDM SAETKKELIQ
DAQRRQNIAY KFSLTIGLDR DAGGTMVEGY LERLNKLLMC CDKCVHNWHI GRKAYLKELA
ENFDDETVAA LSSRLNVLDF QRIDNGLERS KKVISEVESP MRTQKLLAGY DSSLLLSLYE
SLCCVDYHKS ADNLSKHFDF VFEEIQAKKV LRISDILPAT GRFLFDKNPI RQRFARCAWQ
KATTMLTSTS FDWVVHDALS DAIASVTQGN YDYEDIIRFW EGFLLILEKL DEHLITHSLR
AMEVQPSVYI LALNHLSCKS ERINKLVIEA LRGLLKKSPK NFWAAFATIS PAVVAENILR
SWGVKEKLQT IKFEDPETSF ILAWLPELVE SLPSDRQYDV CSFVLRFLGG YQTSEHPENT
QLACRCAALD TLRATLSTFV DSEYIINPST SLIFINNIMG LVDDYKETIT ESADLKVENT
THQEMRRLGM LVIRDALALD CKALSAEFQA LAGDIPIQQG LRSHSQPIWQ GVLDIFRPGN
VDLAKSILAA TTHLTGLDEL TPKSKKLPLP SSHLQYNKDF RQLTENVSRI FERLSDFNAS
HLIEMYRDTQ TSRPLFAALM SADQQIFEAA VEVVKAATDQ ISKREAMSSL LEQAFVPMLN
SLTFAVVRIT KAKNFSPVPY LFKVGRDTLD ALCGNTGFLR THPSLDSTER GAVMSWWVNQ
WRALDAAFAN TEAWGGRVQL PKETLQDFCR DGMEYAESLF DKNSVIASAL CESSHSSHAL
SSGYTSTKTA LKKVLQVVCL NVNGLTMMLR LRDIYLVSVI TSLLGKLLRS LAEFDVEVHE
YSLSFIQDAC LNEGEKGYRK TNLTNQQKAE LRAALDEHKG VEIIESYSTT AQKQQSRIDS
WSKSAGGVKH EPTFSVKGRQ TQTSLDTWSK AGDGKTYEPV ITQSNKASQS PFTLSEHNKS
IIEKMRAQPP LKTAKATEDW KDKRRRDEEE KKRRNAAAIA QAKALRAPAA LVKGEGSGLK
NLSGVAGKDH APVRSEIMVG SSDEDSDDDD EDDGSDTKFL FTKSREASNK VREYEESRKK
ALLQATGPVR KTKKVYSKKD LRARLEPNMD IIYLELLNWD IFHEGEDPPS NNVCKKIASS
FLDLGLYKET FKPLLISEVW RSLLTAKEEN QFKPIEIKVL NRLSVDKFME VSTTMSISNQ
RDLMVYQQDI VLLSKSSNPL QDKQAPHCLA RVFRTTRKRD AVEVTYRVSR DISPELLNCF
VPNGKLYTLK ITDMTTTLRE FAALSSLEYY DLCTEILEAK PSPLQKYSDE KVASMSNRYK
LNNGQAKAIL SANDNDGFTL IQGPPGSGKT KTIIAMVGAL LSQVLQQQAQ QVGFRPQGQN
RSAGAQAQAQ APKKKLLICA PSNAAVDELV LRLKEGILPL SGSHQKINVI RVGRSDAINS
SVKDVTLDEL VRIKLEGDQE SKKGQLNDRE VLHRDAGLIK ERLSVLRPEM EKCRAAGDKT
SELKLQREFD ELKRKQAHIG NKIDEDKESD NKVRQNEISR RHFTQEIIDG AHVLCATLSG
SGHDFLRNVN VEFETVIIDE AAQCIELSAL IPLKYGATKC ILVGDPEQLP PTVLSRLAKS
YGYEQSLFVR MQRNHPDDVH LLDTQYRMHP EISRFPSQQF YNSRLIDGDG MAQLRVQPWH
ASSILGPYRF FDVVGVQSKE ARGHSLINVP ELNAAIQLYQ RLKTDYRSYD FRGKIGIITT
YKAQLNELKR RFGAKFGDEI FEEIEFNTTD AFQGREREII IFSCVRAKAA GGIGFLNDIR
RMNVGLTRAK SSLWVLGDSR ALEQGEFWNR LIQDAKSRER YTSGDIMGLL SRPTSKDAPV
IDYSKISSEI NSNISRLPSE KSDSDIDMTD APQNRSSRES VSGSSSTTSV DGRNTPNNVE
TGEQRKRPRE QELHPDNITT KKKKKTPTAE ADPAPPASAM LNRGPVEPQK LDLEAALQAQ
QANKAAAAAA RIPKSNLPPP PRRKAPADPF IQRKPPKRK
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