ID   M7WW92_RHOT1            Unreviewed;       810 AA.
AC   M7WW92;
DT   29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2013, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   SubName: Full=Heparinase II/III family protein {ECO:0000313|EMBL:EMS22120.1};
GN   ORFNames=RHTO_00874 {ECO:0000313|EMBL:EMS22120.1};
OS   Rhodotorula toruloides (strain NP11) (Yeast) (Rhodosporidium toruloides).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC   Microbotryomycetes; Sporidiobolales; Sporidiobolaceae; Rhodotorula.
OX   NCBI_TaxID=1130832 {ECO:0000313|EMBL:EMS22120.1, ECO:0000313|Proteomes:UP000016926};
RN   [1] {ECO:0000313|EMBL:EMS22120.1, ECO:0000313|Proteomes:UP000016926}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NP11 {ECO:0000313|EMBL:EMS22120.1,
RC   ECO:0000313|Proteomes:UP000016926};
RX   PubMed=23047670; DOI=10.1038/ncomms2112;
RA   Zhu Z., Zhang S., Liu H., Shen H., Lin X., Yang F., Zhou Y.J., Jin G.,
RA   Ye M., Zou H., Zou H., Zhao Z.K.;
RT   "A multi-omic map of the lipid-producing yeast Rhodosporidium toruloides.";
RL   Nat. Commun. 3:1112-1112(2012).
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DR   EMBL; KB722652; EMS22120.1; -; Genomic_DNA.
DR   RefSeq; XP_016273239.1; XM_016414558.1.
DR   AlphaFoldDB; M7WW92; -.
DR   GeneID; 27364887; -.
DR   eggNOG; ENOG502QUTC; Eukaryota.
DR   HOGENOM; CLU_008982_1_0_1; -.
DR   OrthoDB; 2204041at2759; -.
DR   Proteomes; UP000016926; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016829; F:lyase activity; IEA:InterPro.
DR   Gene3D; 2.70.98.70; -; 1.
DR   Gene3D; 1.50.10.100; Chondroitin AC/alginate lyase; 1.
DR   InterPro; IPR008929; Chondroitin_lyas.
DR   InterPro; IPR012480; Hepar_II_III.
DR   PANTHER; PTHR38045; CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE; 1.
DR   PANTHER; PTHR38045:SF1; CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE; 1.
DR   Pfam; PF07940; Hepar_II_III; 1.
DR   SUPFAM; SSF48230; Chondroitin AC/alginate lyase; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        55..76
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          82..104
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          726..760
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   810 AA;  88234 MW;  FE82E5D22BD2D288 CRC64;
     MYHQRQDSVG SAIPLHNYSY QQAPGGNEQG YGSAYGEKQY PQGKAAGSRR HPWRWIIGAL
     VLIAVILGAV LGGVFGSRAA NDNKKSDAAS GADNKGASGS GVANAATRTK GSGGFAIVPT
     ATDQFGNPMY PTSTGSAHIS APTVVSNSSL SCQADSTSGL SLTSPKTSHP LLIATENKWN
     CLPQLIAQDS YMSYWNDTIF LNATKFYDMP PTNYSIDGGL TGSGVLDVAR EVQLRIKHWA
     YAYRLSNDTK WVDRTWRELV VASGNDTSQY FGQDNKGGDV WNSGHFLDLA EFTEAFALAY
     DWMYDAWTQQ QRTAIAWSIV NLGLRYGVNA FADPSGAGAS YSWWTKVDGN WNCVCNKGMT
     MGALAIINED PTNGIAKQIL GYTVPNAVEY CSFAPSPEGT WSETANYWYF GTYSHVEMAA
     ALLSATGSTQ NMLDANPGMK LSATYHMYVT GMQGLFNYGD CGPNKYTATA NGLMFYGNQY
     NMPVYTLFQR DRGDAPEPMS MLYYDPQVSG QFWDNLPLDH HFSNTTDGWF SARSSWTDND
     GIYIAMKAGK LTGHQTHGDL DAGDFVLDAM GQRWAGELGS GDYLSNGYFS SEDQNSPRWL
     YYRKRTEGQN TLLIGDADQN VAGTPQTTFQ STGEAQDALD YTPTNSSTAF FTADLSEMYN
     STTSVKRAIR FINGRHQVLL RDEVDSSAAV QWRMNTNATV ALSNNNQQAT LTLGGQTLIM
     QLRSPSGAQF ATAQPERQSS DPTTTNYGGS NVQMSPDQPN PGVTVVTVDV AAGNNVIEVL
     FNPQWKSFKS SDYLTPPSVA IDSWSLTSHN
//