ID M7Z1D0_TRIUA Unreviewed; 340 AA.
AC M7Z1D0;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Trans-2,3-enoyl-CoA reductase {ECO:0000313|EMBL:EMS46140.1};
GN ORFNames=TRIUR3_25686 {ECO:0000313|EMBL:EMS46140.1};
OS Triticum urartu (Red wild einkorn) (Crithodium urartu).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4572 {ECO:0000313|EMBL:EMS46140.1};
RN [1] {ECO:0000313|EMBL:EMS46140.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23535596; DOI=10.1038/nature11997;
RA Ling H.Q., Zhao S., Liu D., Wang J., Sun H., Zhang C., Fan H., Li D.,
RA Dong L., Tao Y., Gao C., Wu H., Li Y., Cui Y., Guo X., Zheng S., Wang B.,
RA Yu K., Liang Q., Yang W., Lou X., Chen J., Feng M., Jian J., Zhang X.,
RA Luo G., Jiang Y., Liu J., Wang Z., Sha Y., Zhang B., Wu H., Tang D.,
RA Shen Q., Xue P., Zou S., Wang X., Liu X., Wang F., Yang Y., An X., Dong Z.,
RA Zhang K., Zhang X., Luo M.C., Dvorak J., Tong Y., Wang J., Yang H., Li Z.,
RA Wang D., Zhang A., Wang J.;
RT "Draft genome of the wheat A-genome progenitor Triticum urartu.";
RL Nature 496:87-90(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the steroid 5-alpha reductase family.
CC {ECO:0000256|ARBA:ARBA00007742}.
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DR EMBL; KD277986; EMS46140.1; -; Genomic_DNA.
DR AlphaFoldDB; M7Z1D0; -.
DR STRING; 4572.M7Z1D0; -.
DR eggNOG; KOG1639; Eukaryota.
DR OMA; WSTAAWM; -.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR InterPro; IPR001104; 3-oxo-5_a-steroid_4-DH_C.
DR InterPro; IPR039357; SRD5A/TECR.
DR PANTHER; PTHR10556; 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE; 1.
DR PANTHER; PTHR10556:SF28; VERY-LONG-CHAIN ENOYL-COA REDUCTASE; 1.
DR Pfam; PF02544; Steroid_dh; 1.
DR PROSITE; PS50244; S5A_REDUCTASE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 180..249
FT /note="Steroid 5-alpha reductase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50244"
SQ SEQUENCE 340 AA; 39012 MW; D4F9ED594E5ACC82 CRC64;
MEKSELLSWR IEYYNPDAKK YYPARQRLTL PAQPGKSGKP VVLSQKASLS EYCEKGSGSL
TVVFKDLGPQ VYYSTLFFWE YVGPLIIYPI FYYLPVYKYF GYEGERVIHP VQTYAMYYFC
FHYFKRIMET FFVHRFSHAT SPVSNVFRNC AYYWTFGAYI AYYCNHPLYT PVSDLQMKIG
FGIGVVCQIA NFYCHILLRN LRSPTGSGGY QIPRGFLFNI VTCANYTTEI YQWLGFNIAT
QTVAGYVFLA VAGAVRREGR AAQVPPPMGD SSSIPVKKSR CSQGLHLEIQ HLFCSSVPKL
KAISRFHSNI PTNRALYQLS NLNYVVQMFL SEGCIFLLPL
//
