ID M7ZK00_TRIUA Unreviewed; 1059 AA.
AC M7ZK00;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=Alpha-mannosidase {ECO:0000256|RuleBase:RU361199};
DE EC=3.2.1.- {ECO:0000256|RuleBase:RU361199};
GN ORFNames=TRIUR3_16376 {ECO:0000313|EMBL:EMS63528.1};
OS Triticum urartu (Red wild einkorn) (Crithodium urartu).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4572 {ECO:0000313|EMBL:EMS63528.1};
RN [1] {ECO:0000313|EMBL:EMS63528.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23535596; DOI=10.1038/nature11997;
RA Ling H.Q., Zhao S., Liu D., Wang J., Sun H., Zhang C., Fan H., Li D.,
RA Dong L., Tao Y., Gao C., Wu H., Li Y., Cui Y., Guo X., Zheng S., Wang B.,
RA Yu K., Liang Q., Yang W., Lou X., Chen J., Feng M., Jian J., Zhang X.,
RA Luo G., Jiang Y., Liu J., Wang Z., Sha Y., Zhang B., Wu H., Tang D.,
RA Shen Q., Xue P., Zou S., Wang X., Liu X., Wang F., Yang Y., An X., Dong Z.,
RA Zhang K., Zhang X., Luo M.C., Dvorak J., Tong Y., Wang J., Yang H., Li Z.,
RA Wang D., Zhang A., Wang J.;
RT "Draft genome of the wheat A-genome progenitor Triticum urartu.";
RL Nature 496:87-90(2013).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|RuleBase:RU361199};
CC Note=Binds 1 zinc ion per subunit. {ECO:0000256|RuleBase:RU361199};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC {ECO:0000256|ARBA:ARBA00009792, ECO:0000256|RuleBase:RU361199}.
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DR EMBL; KD067823; EMS63528.1; -; Genomic_DNA.
DR AlphaFoldDB; M7ZK00; -.
DR STRING; 4572.M7ZK00; -.
DR eggNOG; KOG1958; Eukaryota.
DR OMA; WRQNWDM; -.
DR GO; GO:0005794; C:Golgi apparatus; IEA:EnsemblPlants.
DR GO; GO:0004559; F:alpha-mannosidase activity; IEA:EnsemblPlants.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0042538; P:hyperosmotic salinity response; IEA:EnsemblPlants.
DR GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR GO; GO:0000272; P:polysaccharide catabolic process; IEA:UniProt.
DR GO; GO:0006487; P:protein N-linked glycosylation; IEA:EnsemblPlants.
DR CDD; cd10809; GH38N_AMII_GMII_SfManIII_like; 1.
DR Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR InterPro; IPR011682; Glyco_hydro_38_C.
DR InterPro; IPR015341; Glyco_hydro_38_cen.
DR InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR InterPro; IPR000602; Glyco_hydro_38_N.
DR InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR InterPro; IPR013780; Glyco_hydro_b.
DR PANTHER; PTHR11607; ALPHA-MANNOSIDASE; 1.
DR PANTHER; PTHR11607:SF3; LYSOSOMAL ALPHA-MANNOSIDASE; 1.
DR Pfam; PF09261; Alpha-mann_mid; 1.
DR Pfam; PF07748; Glyco_hydro_38C; 1.
DR Pfam; PF01074; Glyco_hydro_38N; 1.
DR SMART; SM00872; Alpha-mann_mid; 1.
DR SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361199};
KW Hydrolase {ECO:0000256|RuleBase:RU361199};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU361199};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU361199}.
FT DOMAIN 387..472
FT /note="Glycoside hydrolase family 38 central"
FT /evidence="ECO:0000259|SMART:SM00872"
SQ SEQUENCE 1059 AA; 122122 MW; 5E1D56FFBFBF9483 CRC64;
MGFISYCLNL FLYIMSSYLM CYYVLHKLNT LNADLTFGWE VTYKGDEWDA EKLKVFVAPH
SHNDPGWIHT VEEYYDRQSR HILDTIIESL SKDPRRKFIW EEMSYLERWW RDAPRKKQEE
FAKLVHDGQL EIVSGGWVMN DEMMEGNMWL NDTIGVIPKN SWSIDPFGYS STMAYLLRRM
GFHNMLIQRT HYELKKELAR KQNLEYLWRQ NWDIEETTDI FVHMMPFYSY DIPHTCGPEP
AICCQFDFAR MRGFSYESCP WRYDPVETDS NNVQERATKL LDQYRKKSTL YRTNTLLIPL
GDDFRYVNTE EAEAQFRNYE KLFDYINSNP HLNAEVKFGT LEDYFSTLRD EAEKINYTRP
GEVGSVELQG FPTLSGDFFT YADRNQDYWS GYYVSRPFFK AVDRVLEQTL RASEILSSFV
LGYCQKFQCA KLPISFSHKL TAARRNLALF QHHDGVTGTA KDHVVVDYGT RMHTSLQDLQ
LFMSRAVEVL LGDVHDRSDP TILSHFEPVQ ERSKYDVQPV HRVLNPHEGK THSVVFFNPL
EQTRDEIVMI VVSNPDVSVL NSTGSCLKCQ ISPEWQYASG EKFSTGRHRL YWRASVPALG
LETYYVAVGQ DCEKATPAVV KTFTASQEFS CPEPYHCSNL EGKTVEMKNS YHTLSFDVSR
GLLQTVTRHK HGEKTEIGEE IAMYSSRGSG AYLFKPIGEA RPIVKEGGYF ILTEGPLVQE
AHSLPKTEWD KSPLSHSTRI YSCGDSIQDM LVEKEYHVEL VGRVFDDREL IVRYKTDIDN
QRVFYSDLNG FQMSRRQTYD KIPLQGNYYP MPSLAFLQDS LGNRFSVHSK QSLGAASLKK
GWMEIMLDRR LVRDDGRGLG QGVMDNRPMN VIFHLLMESN VSALPKSHNS ITLQPSLLSH
RVGAHLNYPM HAFVSKNLHE KSFKLPQQTF TPLATSLPCD IHVVNLKVPQ PLRFAHTEAV
EPRFAILLQR RGWDASYCKR GGLQCTNIGE EAVNLFDMFK DLSVLNVKAT SLNLLNDDPE
MLGYLEQIGD VAQEGNVLIS PMEIQAYKLD LQPPSSPEE
//
