ID M8A321_TRIUA Unreviewed; 629 AA.
AC M8A321;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Zinc-binding alcohol dehydrogenase domain-containing protein 2 {ECO:0000313|EMBL:EMS54819.1};
GN ORFNames=TRIUR3_16107 {ECO:0000313|EMBL:EMS54819.1};
OS Triticum urartu (Red wild einkorn) (Crithodium urartu).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4572 {ECO:0000313|EMBL:EMS54819.1};
RN [1] {ECO:0000313|EMBL:EMS54819.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23535596; DOI=10.1038/nature11997;
RA Ling H.Q., Zhao S., Liu D., Wang J., Sun H., Zhang C., Fan H., Li D.,
RA Dong L., Tao Y., Gao C., Wu H., Li Y., Cui Y., Guo X., Zheng S., Wang B.,
RA Yu K., Liang Q., Yang W., Lou X., Chen J., Feng M., Jian J., Zhang X.,
RA Luo G., Jiang Y., Liu J., Wang Z., Sha Y., Zhang B., Wu H., Tang D.,
RA Shen Q., Xue P., Zou S., Wang X., Liu X., Wang F., Yang Y., An X., Dong Z.,
RA Zhang K., Zhang X., Luo M.C., Dvorak J., Tong Y., Wang J., Yang H., Li Z.,
RA Wang D., Zhang A., Wang J.;
RT "Draft genome of the wheat A-genome progenitor Triticum urartu.";
RL Nature 496:87-90(2013).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
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DR EMBL; KD177905; EMS54819.1; -; Genomic_DNA.
DR AlphaFoldDB; M8A321; -.
DR STRING; 4572.M8A321; -.
DR eggNOG; KOG1196; Eukaryota.
DR eggNOG; KOG4169; Eukaryota.
DR OMA; TNEPLVY; -.
DR OrthoDB; 535799at2759; -.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd05323; ADH_SDR_c_like; 1.
DR CDD; cd08250; Mgc45594_like; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR InterPro; IPR002364; Quin_OxRdtase/zeta-crystal_CS.
DR InterPro; IPR020904; Sc_DH/Rdtase_CS.
DR InterPro; IPR002347; SDR_fam.
DR PANTHER; PTHR43677:SF3; PROSTAGLANDIN REDUCTASE 3; 1.
DR PANTHER; PTHR43677; SHORT-CHAIN DEHYDROGENASE/REDUCTASE; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00106; adh_short; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR PRINTS; PR00081; GDHRDH.
DR PRINTS; PR00080; SDRFAMILY.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
DR PROSITE; PS00061; ADH_SHORT; 1.
DR PROSITE; PS01162; QOR_ZETA_CRYSTAL; 1.
PE 4: Predicted;
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 304..616
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 629 AA; 67987 MW; 555415B3CBD6A84E CRC64;
MELKPGMSAL VTGGASGIGK ALCIAFAQKG LFVTVVDFSE QNGREVTSLV QKENRKFHGD
LGVPSAIFVK CDVSIEGDLA AAFAKHVDTY GGLDICINCA GIANKTLVYY DTSDGTRTWR
HAINVNFVAV IDGTRIASQI MRSRKKPGVI INIGSAAGLY PMFADPIYTG TKGGVVMFTR
SLAPLKRHGV RVNVLCPEFV QTNMAEQINQ KIVHATGGFL KMEEVVNGAF ELIKDESKAG
ACLWITKRRG MEYWPSAEEQ RKYLLNYTKS KRTVTKNVFP SIQTPEFYEK IVVHTLSHNF
RNATRLDRVR LRLPIEPQSA LVKIIYAGVN ASDVNFSSGR YFSGSAKETA ARLPFDAGFE
AVGIVASVGD AVSHVKVGSP VALMTFGSYA EFTMVPAKHL LPVPRPDPEV VAMLTSGLTA
SISLEKAGQM TSGQVVLVTA AAGGTGQFAV QLAKLAGNKV VATCGGESKA AFLASLGVDR
VINYQHEKIK DVLKKEFPKG VDIIYESVGG DMFDLCLNAL AVHGRLIVIG MISQYQGEEG
WKPKNYTGLC EKILAKSQTV AGFFLVQHAH MWQDHLDKLF ELYASGKLKV SLDPKKFLGV
ASAVDAVEES VGKVVVCIDP AYSQTLAKL
//
