ID M8DED8_9BACL Unreviewed; 345 AA.
AC M8DED8;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=3-oxoacyl-(Acyl carrier protein) synthase III {ECO:0000313|EMBL:EMT51767.1};
DE EC=2.3.1.180 {ECO:0000313|EMBL:EMT51767.1};
GN ORFNames=I532_15531 {ECO:0000313|EMBL:EMT51767.1};
OS Brevibacillus borstelensis AK1.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Brevibacillus.
OX NCBI_TaxID=1300222 {ECO:0000313|EMBL:EMT51767.1, ECO:0000313|Proteomes:UP000012081};
RN [1] {ECO:0000313|EMBL:EMT51767.1, ECO:0000313|Proteomes:UP000012081}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AK1 {ECO:0000313|EMBL:EMT51767.1,
RC ECO:0000313|Proteomes:UP000012081};
RA Rajan I., PoliReddy D., Sugumar T., Rathinam K., Alqarawi S., Khalil A.B.,
RA Sivakumar N.;
RT "Assembly of a new bacterial strain Brevibacillus borstelensis AK1.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. FabH family.
CC {ECO:0000256|ARBA:ARBA00008642}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMT51767.1}.
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DR EMBL; APBN01000006; EMT51767.1; -; Genomic_DNA.
DR RefSeq; WP_003389344.1; NZ_APBN01000006.1.
DR AlphaFoldDB; M8DED8; -.
DR STRING; 1300222.I532_15531; -.
DR GeneID; 72736179; -.
DR PATRIC; fig|1300222.3.peg.3251; -.
DR OrthoDB; 9815506at2; -.
DR Proteomes; UP000012081; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0033818; F:beta-ketoacyl-acyl-carrier-protein synthase III activity; IEA:UniProtKB-EC.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd00830; KAS_III; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR013747; ACP_syn_III_C.
DR InterPro; IPR013751; ACP_syn_III_N.
DR InterPro; IPR004655; FabH.
DR InterPro; IPR016039; Thiolase-like.
DR NCBIfam; TIGR00747; fabH; 1.
DR PANTHER; PTHR34069; 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 3; 1.
DR PANTHER; PTHR34069:SF2; BETA-KETOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE III; 1.
DR Pfam; PF08545; ACP_syn_III; 1.
DR Pfam; PF08541; ACP_syn_III_C; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000313|EMBL:EMT51767.1}; Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Fatty acid biosynthesis {ECO:0000256|ARBA:ARBA00023160};
KW Fatty acid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Multifunctional enzyme {ECO:0000256|ARBA:ARBA00023268};
KW Reference proteome {ECO:0000313|Proteomes:UP000012081};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EMT51767.1}.
FT DOMAIN 124..201
FT /note="Beta-ketoacyl-[acyl-carrier-protein] synthase III N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF08545"
FT DOMAIN 253..341
FT /note="Beta-ketoacyl-[acyl-carrier-protein] synthase III C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF08541"
SQ SEQUENCE 345 AA; 37292 MW; D2AC57D65CA761C3 CRC64;
MKTGTLTKPS TVNQSGLATS FSIQGSGFYV PEDIVTNEML TRTLDTTDEW IQDKTGIRER
RYLQSDMATS DMCVQASLDA ISDAGITSED IDAIVLCTTT PDQQIPSTAL IVKEKIGAKN
AIPFDLTQGA CAGGIYSILF ASHLLQNQFI NNVLVIGAEV LSRYIDPTDR ITKTFFGDAA
GAILLQKTGE GSGLLAWDLD SYLNLAVTLH GGGTARMPEG ADLKTSHFIR MNGREVWKTA
TRNLPLSIKN AVHKAGLQVS DIDHFILHQA NLNIIKKTMA ALDVPMEKTT VTIQDYGNTG
AASIFSALHK SLEEKAIKPG DYLVISAIGA GFLWGSLCLQ YTKNE
//
