ID M8E286_9BACL Unreviewed; 409 AA.
AC M8E286;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Efflux system {ECO:0000313|EMBL:EMT53391.1};
GN ORFNames=I532_05245 {ECO:0000313|EMBL:EMT53391.1};
OS Brevibacillus borstelensis AK1.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Brevibacillus.
OX NCBI_TaxID=1300222 {ECO:0000313|EMBL:EMT53391.1, ECO:0000313|Proteomes:UP000012081};
RN [1] {ECO:0000313|EMBL:EMT53391.1, ECO:0000313|Proteomes:UP000012081}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AK1 {ECO:0000313|EMBL:EMT53391.1,
RC ECO:0000313|Proteomes:UP000012081};
RA Rajan I., PoliReddy D., Sugumar T., Rathinam K., Alqarawi S., Khalil A.B.,
RA Sivakumar N.;
RT "Assembly of a new bacterial strain Brevibacillus borstelensis AK1.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMT53391.1}.
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DR EMBL; APBN01000002; EMT53391.1; -; Genomic_DNA.
DR AlphaFoldDB; M8E286; -.
DR STRING; 1300222.I532_05245; -.
DR PATRIC; fig|1300222.3.peg.1073; -.
DR Proteomes; UP000012081; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 2.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 3.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR039562; MFP_biotin_lipoyl_2.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF13533; Biotin_lipoyl_2; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 3.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000012081};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..409
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004095418"
FT DOMAIN 64..110
FT /note="Membrane fusion protein biotin-lipoyl like"
FT /evidence="ECO:0000259|Pfam:PF13533"
FT DOMAIN 163..325
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT COILED 129..194
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 409 AA; 43403 MW; B1E4271F0767553E CRC64;
MRKQPIILAL SVALLIAGCS QPEAAAPSDT QAEEAATPVQ IEQVKKGVVS SEAGISAKLA
PSEEIQISPK VSGKITSLPV KLGQPVKKGE VLFKLDETDL ANTVAQQEAA YKVALANLKQ
SGSSTDQSLV QAQNSLKQAE QALTDAQLNQ QRMKQLFDQG AISSQQFEQA NTSLMNAQTA
YENAKQTLET TKQKTTLQVS EASVNQAAVA LQNAREQLAN AVVTAPISGF VSSVNGAVGQ
IASQGTPVVV IVNTNPLLVK ANLSEQDITK VKVGTAVKVN IPILGKEVEA KVSAVSPVMN
SQLKAYPIEI SIPNPSNELK ADMVVNVTFA GQVSGKEEEL IVPRKAVFER EGKKFVFRIE
DEVAKQVEVT TGEETSDQIV IKSGLAEGDK VVVKGQTLLQ DGKKVSIIQ
//
