ID M9LWI8_PSEA3 Unreviewed; 364 AA.
AC M9LWI8;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Flavonol reductase {ECO:0000313|EMBL:GAC71110.1};
GN ORFNames=PANT_1c00003 {ECO:0000313|EMBL:GAC71110.1};
OS Pseudozyma antarctica (strain T-34) (Yeast) (Candida antarctica).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Moesziomyces.
OX NCBI_TaxID=1151754 {ECO:0000313|EMBL:GAC71110.1, ECO:0000313|Proteomes:UP000011976};
RN [1] {ECO:0000313|Proteomes:UP000011976}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T-34 {ECO:0000313|Proteomes:UP000011976};
RX PubMed=23558529; DOI=10.1128/genomea.00064-13;
RA Morita T., Koike H., Koyama Y., Hagiwara H., Ito E., Fukuoka T., Imura T.,
RA Machida M., Kitamoto D.;
RT "Genome sequence of the basidiomycetous yeast Pseudozyma antarctica T-34, a
RT producer of the glycolipid biosurfactants mannosylerythritol lipids.";
RL Genome Announc. 1:E0006413-E0006413(2013).
CC -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC family. Dihydroflavonol-4-reductase subfamily.
CC {ECO:0000256|ARBA:ARBA00023445}.
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DR EMBL; DF196767; GAC71110.1; -; Genomic_DNA.
DR AlphaFoldDB; M9LWI8; -.
DR STRING; 1151754.M9LWI8; -.
DR OrthoDB; 987679at2759; -.
DR Proteomes; UP000011976; Unassembled WGS sequence.
DR GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
DR CDD; cd05227; AR_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR002225; 3Beta_OHSteriod_DH/Estase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10366:SF849; FATTY ACID HYDROXYLASE UHD1; 1.
DR PANTHER; PTHR10366; NAD DEPENDENT EPIMERASE/DEHYDRATASE; 1.
DR Pfam; PF01073; 3Beta_HSD; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000011976}.
FT DOMAIN 11..183
FT /note="3-beta hydroxysteroid dehydrogenase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF01073"
FT REGION 294..314
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 364 AA; 40033 MW; 6BAF62BDDA5FD2C0 CRC64;
MPAIQPKSHV LVTGGSGFIA VWCVYQLLER GHKVRTTVRS DAKGKYLQDL FKKYGDQLSF
VIAEDLEKQG AFDDAVKGVD AVLHTASPFH FNIDGDPRGT LINPAVNGTR NVLTSIHKHG
KDVKRVVITS SFAAILDSTR KGHIVYTEKD WNISSVENVE KQGKDQEGPD AYRASKTMAE
RAAWQFVEEN KPEWDLVTIN PPLVLGPILH QVAAPEKLNT SVGFVWGLLH GSKKEDDLLA
PSGNCVDVRD VAYAHVEALV RADAGGNRFA TSLGPFVWQD VADVIHADDA VPSEWKKQVP
QGKHGEGSSV KQNELDGSKA TRVLDLRYIQ MQDVVKDMVA SLADYEKRGW SGVPSDHLLS
LTKH
//
