ID   M9M000_PSEA3            Unreviewed;      1243 AA.
AC   M9M000;
DT   29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2013, sequence version 1.
DT   22-FEB-2023, entry version 30.
DE   SubName: Full=Nonsense-mediated mRNA decay 2 protein {ECO:0000313|EMBL:GAC73050.1};
GN   ORFNames=PANT_8c00042 {ECO:0000313|EMBL:GAC73050.1};
OS   Pseudozyma antarctica (strain T-34) (Yeast) (Candida antarctica).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC   Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Moesziomyces.
OX   NCBI_TaxID=1151754 {ECO:0000313|EMBL:GAC73050.1, ECO:0000313|Proteomes:UP000011976};
RN   [1] {ECO:0000313|Proteomes:UP000011976}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=T-34 {ECO:0000313|Proteomes:UP000011976};
RX   PubMed=23558529; DOI=10.1128/genomea.00064-13;
RA   Morita T., Koike H., Koyama Y., Hagiwara H., Ito E., Fukuoka T., Imura T.,
RA   Machida M., Kitamoto D.;
RT   "Genome sequence of the basidiomycetous yeast Pseudozyma antarctica T-34, a
RT   producer of the glycolipid biosurfactants mannosylerythritol lipids.";
RL   Genome Announc. 1:E0006413-E0006413(2013).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR   EMBL; DF196774; GAC73050.1; -; Genomic_DNA.
DR   AlphaFoldDB; M9M000; -.
DR   STRING; 1151754.M9M000; -.
DR   OrthoDB; 276824at2759; -.
DR   Proteomes; UP000011976; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:InterPro.
DR   Gene3D; 1.25.40.180; -; 3.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR003890; MIF4G-like_typ-3.
DR   InterPro; IPR039762; Nmd2/UPF2.
DR   InterPro; IPR007193; Upf2/Nmd2_C.
DR   PANTHER; PTHR12839; NONSENSE-MEDIATED MRNA DECAY PROTEIN 2 UP-FRAMESHIFT SUPPRESSOR 2; 1.
DR   PANTHER; PTHR12839:SF7; REGULATOR OF NONSENSE TRANSCRIPTS 2; 1.
DR   Pfam; PF02854; MIF4G; 2.
DR   Pfam; PF04050; Upf2; 1.
DR   SMART; SM00543; MIF4G; 2.
DR   SUPFAM; SSF48371; ARM repeat; 2.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011976}.
FT   DOMAIN          485..674
FT                   /note="MIF4G"
FT                   /evidence="ECO:0000259|SMART:SM00543"
FT   DOMAIN          689..898
FT                   /note="MIF4G"
FT                   /evidence="ECO:0000259|SMART:SM00543"
FT   REGION          11..39
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          438..475
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          921..1113
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1190..1243
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        935..950
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        971..1015
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1027..1056
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1063..1085
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1190..1211
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1216..1230
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1243 AA;  136776 MW;  7CEADEE092DAC99C CRC64;
     MVAAAAALVA SSAASGSPAV PSAKDDSQAQ ALHRERDRKR RQLRAVNVGV WSAGPAPPSQ
     SLDSNLKKNT AYIKRAKQSI GHDARDQLLK DLPQLNLEKY LQELIQAVSE GLGRCVTAKD
     CLAATEIISA FHARFGSTTF SEPLTTSLEH ALAPPSKTLY QSATTEQKER DEAARVARQK
     PLLRITAELA LVDVVGHTRD APTGCDWLFN VIKALLATDK DHANVPLLIS VLKGLGQTLL
     SPAASLTRDD DSLLADKASG ALIIGDAVNV PDFAALDPAS APLVSSEMQA KFRKLFETYF
     QTLARRVVKE HQRLQDQDRK NHEAYIRSGE IFEDRQQNYE RMTKSFERVR DWARILSDLL
     GVDMPDLESS ASATTAVGLG VNLDSKSAFE RADEEFAPDQ SPWEDQDSQK FYEDLLDLGD
     IIPPSILAQT TGINAASSAN ADKQDAAEDS ANRTEEGKTS TAASTPQLDA DAGDEAMNAG
     PAAQLATLMA KLPDMTNRSM IDSAAVDFAF IATKPARRKL VKHLASLPRN RIDLAPYYAR
     LAATLSRYMP DIGPGLTALL EDEFRYLQRK KNVDLTETRA KNARFLSELT KFKVTPTHAI
     LHCFKTCLED FSGPNVEVVA SLLEGCGRYL LRTEDTSVKM RSMLEMLRRK RAAANLDSRQ
     LLLLNNAYYQ CNPPKRKAIE QKVRSPLELY IRHLIYHLLA KKTVDTVVLQ LRKLAWDDAS
     VYGWLKDAFT RAWRIRYSNI HLLAILVYDL DRFHPSFAVD VIDQVLENIR IGMEENIFKH
     NQRRVATACY LGELYNYRLV NSGIVFEQLW SMVTFGHPKG RPWPSQVAPL DAPDDYFRIR
     LICTLLDTCG VCFDRGSLRK KLDDFLVFLN FYVLCKQQPL PMDVDFTLTE TLEALRPELK
     FKKTFGEAAA ALEEMMAANR QLAPQAEADA EEESDGNSSD ARRHGSRADA HEASAPQGSG
     KRRRNKARNQ AASDASDSED SSDSSSSSSS SSDSSESASS SSLGDSDASD SDGSDSGSSD
     ADDSDDEQAA AERHLLNEEL AARREADDEF DRELARMMVE SSAPGTATAQ SSAGASTSQR
     PHQFFSRAAL PSGGASYGPA HSHAHAHASG SSLSEIGLPI KKKAAEQANG GVEAEAGSHM
     KFSLLSKKGS KQVTHEVYVP ATASIAINTR TKQLKEEAER RQLKQQILAY ERSSESQQHS
     GLQPHGVMRR QQPQQHQHHH KEDPANKAAS KGDDFKIWTS HGF
//