ID M9ME72_PSEA3 Unreviewed; 984 AA.
AC M9ME72;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Coatomer subunit beta {ECO:0000256|PIRNR:PIRNR005727};
DE AltName: Full=Beta-coat protein {ECO:0000256|PIRNR:PIRNR005727};
GN ORFNames=PANT_14c00014 {ECO:0000313|EMBL:GAC75048.1};
OS Pseudozyma antarctica (strain T-34) (Yeast) (Candida antarctica).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Moesziomyces.
OX NCBI_TaxID=1151754 {ECO:0000313|EMBL:GAC75048.1, ECO:0000313|Proteomes:UP000011976};
RN [1] {ECO:0000313|Proteomes:UP000011976}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T-34 {ECO:0000313|Proteomes:UP000011976};
RX PubMed=23558529; DOI=10.1128/genomea.00064-13;
RA Morita T., Koike H., Koyama Y., Hagiwara H., Ito E., Fukuoka T., Imura T.,
RA Machida M., Kitamoto D.;
RT "Genome sequence of the basidiomycetous yeast Pseudozyma antarctica T-34, a
RT producer of the glycolipid biosurfactants mannosylerythritol lipids.";
RL Genome Announc. 1:E0006413-E0006413(2013).
CC -!- FUNCTION: The coatomer is a cytosolic protein complex that binds to
CC dilysine motifs and reversibly associates with Golgi non-clathrin-
CC coated vesicles, which further mediate biosynthetic protein transport
CC from the ER, via the Golgi up to the trans Golgi network. Coatomer
CC complex is required for budding from Golgi membranes, and is essential
CC for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
CC {ECO:0000256|PIRNR:PIRNR005727}.
CC -!- SUBUNIT: Oligomeric complex that consists of at least the alpha, beta,
CC beta', gamma, delta, epsilon and zeta subunits.
CC {ECO:0000256|PIRNR:PIRNR005727}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR005727}. Golgi
CC apparatus membrane {ECO:0000256|ARBA:ARBA00004255,
CC ECO:0000256|PIRNR:PIRNR005727}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004255, ECO:0000256|PIRNR:PIRNR005727};
CC Cytoplasmic side {ECO:0000256|ARBA:ARBA00004255,
CC ECO:0000256|PIRNR:PIRNR005727}. Cytoplasmic vesicle, COPI-coated
CC vesicle membrane {ECO:0000256|PIRNR:PIRNR005727}; Peripheral membrane
CC protein {ECO:0000256|PIRNR:PIRNR005727}; Cytoplasmic side
CC {ECO:0000256|PIRNR:PIRNR005727}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
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DR EMBL; DF196780; GAC75048.1; -; Genomic_DNA.
DR AlphaFoldDB; M9ME72; -.
DR STRING; 1151754.M9ME72; -.
DR OrthoDB; 151169at2759; -.
DR Proteomes; UP000011976; Unassembled WGS sequence.
DR GO; GO:0030126; C:COPI vesicle coat; IEA:InterPro.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR002553; Clathrin/coatomer_adapt-like_N.
DR InterPro; IPR011710; Coatomer_bsu_C.
DR InterPro; IPR016460; COPB1.
DR InterPro; IPR029446; COPB1_appendage_platform_dom.
DR PANTHER; PTHR10635; COATOMER SUBUNIT BETA; 1.
DR PANTHER; PTHR10635:SF0; COATOMER SUBUNIT BETA; 1.
DR Pfam; PF01602; Adaptin_N; 1.
DR Pfam; PF07718; Coatamer_beta_C; 1.
DR Pfam; PF14806; Coatomer_b_Cpla; 1.
DR PIRSF; PIRSF005727; Coatomer_beta_subunit; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|PIRNR:PIRNR005727};
KW Cytoplasmic vesicle {ECO:0000256|PIRNR:PIRNR005727};
KW ER-Golgi transport {ECO:0000256|ARBA:ARBA00022892,
KW ECO:0000256|PIRNR:PIRNR005727};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034,
KW ECO:0000256|PIRNR:PIRNR005727};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR005727};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR005727};
KW Reference proteome {ECO:0000313|Proteomes:UP000011976};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005727}.
FT DOMAIN 24..512
FT /note="Clathrin/coatomer adaptor adaptin-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01602"
FT DOMAIN 698..834
FT /note="Coatomer beta subunit C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07718"
FT DOMAIN 846..974
FT /note="Coatomer beta subunit appendage platform"
FT /evidence="ECO:0000259|Pfam:PF14806"
FT COILED 709..736
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 984 AA; 108523 MW; 572700413916DE2D CRC64;
MASSEAIAYT VVAPDPSSDG IELSTQDLRN NLQRGSDEIK LETLRRIIVS TLNGSPQPNL
LMPIIQYVLP SRNKQLKKML HFYWEVCPKL DEKGNLKQEM ILVCNAIRND LQHPNEYIRG
STLRFLQKVK EPELLEPLIP TIRQCLEHRH SYVRKNAVFC VYSIYQQNEN LIVDAPELME
TFLAAEADTT CKRNAFVLLC HTAPERTVQY LLGLGDQIAS QDELMQLAII ELIRKDCRGD
SPNRPRYIRA VSELLAAPSH SVKYEAATTL TTLTQNAAAV KATASALIEL AVKESDNNVK
LIVLDRLDAL RSKHEHVIDP LVMDLLRVLS SPDMDVRRKA LRIALEMVSS RNIEEVVLLL
KKELMKTVDT SQSSQDKNLE YRQLLIQSIH TCAIKFSEVA SNVVHVLMEF LGDSNNPSAV
DVIAFVREVV EKFPDLRSSI VDKLLRTFTD IKSGKVFRGA LWIVGEYCAS IEDVKEAMQQ
IRKVIGEVPI LAAEERLLEA SSTGVEAEAA AEQTDAGASS SALGAAAKSS AANRVRADGT
YATETAFSSE ANQAARLEAV KSASKPPLRS LLLLGDFYTG TVLASTLTKL VLRFAQLSSD
ATAKNSLRAE AMLIMTSIVR VGQSKFAATP IDEDSVERIM ACVETLASSM QEAEPESEEA
NEVFLHDTKA AYTKMVEHEQ AKQAEKLAKE TKVVKVQPDD LLSFRQFSKK AADDAAEEYE
RELTQATGAA EAAKDDFISK LARVVQLTGF SDPVYAEAYV NVHQFDILLD VLVVNQTAET
LQNLSIEFAT LGDLKLVERP SNYTLAPYSY QSIKATIKVS STETGVIFGN IIYEGAAGTG
TQSAGDAKCV VLNDIHIDIM DYIAPAYCNE AQFRAMWTEF EWENKVNVNT AITDLREYLA
HIMKSTNMSC LTPDASLAGE CGFLSANMYA RSLFGEDALA NLSIELLPDG KTIQGHVRIR
SKTQGIALSL GDKITLAQKA ASKD
//
