ID M9MGS0_PSEA3 Unreviewed; 1626 AA.
AC M9MGS0;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE SubName: Full=Pleiotropic drug resistance proteins {ECO:0000313|EMBL:GAC75457.1};
GN ORFNames=PANT_15c00086 {ECO:0000313|EMBL:GAC75457.1};
OS Pseudozyma antarctica (strain T-34) (Yeast) (Candida antarctica).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Moesziomyces.
OX NCBI_TaxID=1151754 {ECO:0000313|EMBL:GAC75457.1, ECO:0000313|Proteomes:UP000011976};
RN [1] {ECO:0000313|Proteomes:UP000011976}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T-34 {ECO:0000313|Proteomes:UP000011976};
RX PubMed=23558529; DOI=10.1128/genomea.00064-13;
RA Morita T., Koike H., Koyama Y., Hagiwara H., Ito E., Fukuoka T., Imura T.,
RA Machida M., Kitamoto D.;
RT "Genome sequence of the basidiomycetous yeast Pseudozyma antarctica T-34, a
RT producer of the glycolipid biosurfactants mannosylerythritol lipids.";
RL Genome Announc. 1:E0006413-E0006413(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; DF196781; GAC75457.1; -; Genomic_DNA.
DR STRING; 1151754.M9MGS0; -.
DR OrthoDB; 5473955at2759; -.
DR Proteomes; UP000011976; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03233; ABCG_PDR_domain1; 1.
DR CDD; cd03232; ABCG_PDR_domain2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR034001; ABCG_PDR_1.
DR InterPro; IPR034003; ABCG_PDR_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010929; PDR_CDR_ABC.
DR PANTHER; PTHR19241:SF298; ABC MULTIDRUG TRANSPORTER (EUROFUNG); 1.
DR PANTHER; PTHR19241; ATP-BINDING CASSETTE TRANSPORTER; 1.
DR Pfam; PF01061; ABC2_membrane; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR Pfam; PF06422; PDR_CDR; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000011976};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 630..649
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 658..677
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 713..731
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 738..759
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 771..790
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 877..895
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1312..1332
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1344..1364
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1384..1415
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1427..1449
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1455..1474
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1577..1598
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 267..519
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 980..1219
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 95..122
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 136..193
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 930..968
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 97..111
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 136..160
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 170..184
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 942..956
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1626 AA; 177739 MW; DF93B2399233444A CRC64;
MTRRDVNLHG ENKALACALS EPPSSVTTTV PPSTPPDPLA YTILEQAARI ANSSLLPNIV
ANLTSAAAAQ PNTPAMSPHD TSADTSGAPA LEMRQTAPSV ADSQPLARVT STGTWGEPER
GEHVNVDQAL QDFQLARKSS RQSATGSIPQ SPSSGLRGSS AIARALSGGD RPKQPEKINE
NEPDLEAASE GDAYDNDFDL GKWMLTRGAQ AKEEGIDNGK PLGVLWKDLS ITAPGSGGGG
VFVKTLPVAI ANTAWRDPIG VLTTICPPLA KVFAPRNMPT TNLLHSTSGI LKPGEMLLVL
GRPGSGCSTV LRAITSKNHS NVSTSGKILY GGFSPEEINR KYRGEVVFVD EEDTHFPTLT
VGQTLEFALK NKVPHRSRRL QGESRQQFIE TCIDVMLKMF GMSHVRDTIV GDQAIRGVSG
GERKRTTISE ALATRASVIA WDNSTRGLDA STALDYARSL RIITDLAQRS TIATLYQVSE
SIYDLFDRVA VIDQGRCIYY GPRKLARSYF YKLGYDTPDR QTTADFVTAL TDTNQVSFRP
GMEQRAPKTA EDRERAWRQS ELYRQVETEM ASYEDHLAHA EQAEQLKQTV RSEKRKGVNK
GSSYTVSFWD QIVSCIWRQL LVKWGARGDL YVKLFTIISV SFMISSLFYN QSYDSQGVFT
RGGILLFACL FNGWLQLSES FEAVAGRPML SRHRQFAFYR PSAVVLARAL VDIPFLLVQC
FLSSIIIYFL ANLRRDAGAF WIFYVYCFLS SYSLTALYRM CAVFSPGFNE AIRFSVLALN
VLIIWVGYVL RRPQMNWLVW LNYAQPISYA FEGFLANELN YDIECNPAQI VPFGQVRDTA
YQTCSLTGGV PGSIVVPSAD YLSTTFGYSR SHIGRNIGVV IAFAVLYLIP TIIGAEIMNF
GSAGGGVTVF ARTKAAKAKL DASKPAKADD VEEKAAVSAD HPSHATDSNG SITRANSPAA
PGDKEASAKS AEELDKKAIF TWKDVSLQLP TGRKLLDDIT GHVKPGTITA LMGASGAGKT
TLLTALSQRG VAGALSGDIL VDGKPLGPGF QRDTGFVLQG DIHLASQTVR EAIEFSALLR
QPAEISREVK LADAKRAIEL LELEDLQDAL IGVPGFGLGV ERRKRVTIAV ELAAKPDLLL
FLDEPTSGLD SAGAASIIRL IRRLASEGQA ILCTIHQPSA LLFESFDNLL LLQPGGRTAY
FGQIGSERAQ GSDKVREYFE RNGAPACPPT TNVAEYMLEV VAQKSEKPWS ERWKASPEAR
ALRAEVEAIN SERASRPVVE DSRSTREYSA TLKTQIVECT KRQFRDLWRD SAFAYGVLFS
NIVTGFAAGG GFAHLGNSVT DLQYRVFVVF LVILNFPATV NSIISKFWEM RITFVVREGP
SKTYSWIAFM TAFVAVSLPI ALVASVLFFL PSFFLPFYSQ ASTVAGMWYL MIFLVTCYEM
FFSLALAAAC PTPVTAANLL PFLLPFVAIV NGVIKPKATL PAPWSGLIYA NPLYWYVRSM
VGNILHDLPV RCREEDLAIF NPPPGQTCGR YALDWVQSVG GQLLNADATS NCSFCQYQVG
DQFAATLGAT WDFRWKGVGI VAGYTIGQLF LAYLAYWYFT EKGYGLGGGL VLGLFGKVKR
FGKGRK
//
