ID M9NDB7_DROME Unreviewed; 5252 AA.
AC M9NDB7;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=Kismet, isoform E {ECO:0000313|EMBL:AFH03496.1};
GN Name=kis {ECO:0000313|EMBL:AFH03496.1,
GN ECO:0000313|FlyBase:FBgn0266557};
GN Synonyms=136/31 {ECO:0000313|EMBL:AFH03496.1}, 2532
GN {ECO:0000313|EMBL:AFH03496.1}, 5841 {ECO:0000313|EMBL:AFH03496.1},
GN anon-WO0172774.164 {ECO:0000313|EMBL:AFH03496.1}, anon-WO0257455.5
GN {ECO:0000313|EMBL:AFH03496.1}, BEST:GM02209
GN {ECO:0000313|EMBL:AFH03496.1}, CG18326 {ECO:0000313|EMBL:AFH03496.1},
GN CG3660 {ECO:0000313|EMBL:AFH03496.1}, Dmel\CG3696
GN {ECO:0000313|EMBL:AFH03496.1}, DmelPex20
GN {ECO:0000313|EMBL:AFH03496.1}, EC2-7 {ECO:0000313|EMBL:AFH03496.1},
GN EK2-4 {ECO:0000313|EMBL:AFH03496.1}, EP(2)0474
GN {ECO:0000313|EMBL:AFH03496.1}, EP474 {ECO:0000313|EMBL:AFH03496.1},
GN FBtr0078144 {ECO:0000313|EMBL:AFH03496.1}, GM02209
GN {ECO:0000313|EMBL:AFH03496.1}, KIS {ECO:0000313|EMBL:AFH03496.1}, Kis
GN {ECO:0000313|EMBL:AFH03496.1}, KIS-L {ECO:0000313|EMBL:AFH03496.1},
GN Kismet {ECO:0000313|EMBL:AFH03496.1}, kiss
GN {ECO:0000313|EMBL:AFH03496.1}, l(2)07812
GN {ECO:0000313|EMBL:AFH03496.1}, l(2)k08827
GN {ECO:0000313|EMBL:AFH03496.1}, l(2)k11324
GN {ECO:0000313|EMBL:AFH03496.1}, l(2)k13631
GN {ECO:0000313|EMBL:AFH03496.1}, l(2)k14112
GN {ECO:0000313|EMBL:AFH03496.1}, l(2)k16510
GN {ECO:0000313|EMBL:AFH03496.1}, l(2)s3527
GN {ECO:0000313|EMBL:AFH03496.1}, l(2)s4771
GN {ECO:0000313|EMBL:AFH03496.1}, l(2)s4793
GN {ECO:0000313|EMBL:AFH03496.1}, Pex20 {ECO:0000313|EMBL:AFH03496.1},
GN Su(Pc)21AB {ECO:0000313|EMBL:AFH03496.1};
GN ORFNames=CG3696 {ECO:0000313|EMBL:AFH03496.1,
GN ECO:0000313|FlyBase:FBgn0266557}, Dmel_CG3696
GN {ECO:0000313|EMBL:AFH03496.1};
OS Drosophila melanogaster (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7227 {ECO:0000313|EMBL:AFH03496.1, ECO:0000313|Proteomes:UP000000803};
RN [1] {ECO:0000313|EMBL:AFH03496.1, ECO:0000313|Proteomes:UP000000803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A.,
RA An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F.,
RA Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H.,
RA Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E.,
RA Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C.,
RA Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A.,
RA Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C.,
RA Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G.,
RA Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.,
RA Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.;
RT "The genome sequence of Drosophila melanogaster.";
RL Science 287:2185-2195(2000).
RN [2] {ECO:0000313|Proteomes:UP000000803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=12537568;
RA Celniker S.E., Wheeler D.A., Kronmiller B., Carlson J.W., Halpern A.,
RA Patel S., Adams M., Champe M., Dugan S.P., Frise E., Hodgson A.,
RA George R.A., Hoskins R.A., Laverty T., Muzny D.M., Nelson C.R.,
RA Pacleb J.M., Park S., Pfeiffer B.D., Richards S., Sodergren E.J.,
RA Svirskas R., Tabor P.E., Wan K., Stapleton M., Sutton G.G., Venter C.,
RA Weinstock G., Scherer S.E., Myers E.W., Gibbs R.A., Rubin G.M.;
RT "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster
RT euchromatic genome sequence.";
RL Genome Biol. 3:RESEARCH0079-RESEARCH0079(2002).
RN [3] {ECO:0000313|Proteomes:UP000000803}
RP GENOME REANNOTATION.
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT review.";
RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN [4] {ECO:0000313|Proteomes:UP000000803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=12537573;
RA Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R.,
RA Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., Ashburner M.,
RA Celniker S.E.;
RT "The transposable elements of the Drosophila melanogaster euchromatin: a
RT genomics perspective.";
RL Genome Biol. 3:RESEARCH0084.1-RESEARCH0084.20(2002).
RN [5] {ECO:0000313|EMBL:AFH03496.1, ECO:0000313|Proteomes:UP000000803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=12537574;
RA Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A.,
RA Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G.,
RA Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M.,
RA Karpen G.H.;
RT "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.";
RL Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002).
RN [6] {ECO:0000313|EMBL:AFH03496.1, ECO:0000313|Proteomes:UP000000803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=16110336; DOI=10.1371/journal.pcbi.0010022;
RA Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D.,
RA Ashburner M., Anxolabehere D.;
RT "Combined evidence annotation of transposable elements in genome
RT sequences.";
RL PLoS Comput. Biol. 1:166-175(2005).
RN [7] {ECO:0000313|EMBL:AFH03496.1, ECO:0000313|Proteomes:UP000000803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=17569856; DOI=10.1126/science.1139815;
RA Smith C.D., Shu S., Mungall C.J., Karpen G.H.;
RT "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.";
RL Science 316:1586-1591(2007).
RN [8] {ECO:0000313|EMBL:AFH03496.1, ECO:0000313|Proteomes:UP000000803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX PubMed=17569867; DOI=10.1126/science.1139816;
RA Hoskins R.A., Carlson J.W., Kennedy C., Acevedo D., Evans-Holm M.,
RA Frise E., Wan K.H., Park S., Mendez-Lago M., Rossi F., Villasante A.,
RA Dimitri P., Karpen G.H., Celniker S.E.;
RT "Sequence finishing and mapping of Drosophila melanogaster
RT heterochromatin.";
RL Science 316:1625-1628(2007).
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DR EMBL; AE014134; AFH03496.1; -; Genomic_DNA.
DR RefSeq; NP_001245819.1; NM_001258890.1.
DR SMR; M9NDB7; -.
DR EnsemblMetazoa; FBtr0308254; FBpp0300574; FBgn0266557.
DR GeneID; 33185; -.
DR AGR; FB:FBgn0266557; -.
DR CTD; 33185; -.
DR FlyBase; FBgn0266557; kis.
DR VEuPathDB; VectorBase:FBgn0266557; -.
DR GeneTree; ENSGT00940000173541; -.
DR OrthoDB; 22878at2759; -.
DR BioGRID-ORCS; 33185; 1 hit in 3 CRISPR screens.
DR ChiTaRS; kis; fly.
DR GenomeRNAi; 33185; -.
DR Proteomes; UP000000803; Chromosome 2L.
DR Bgee; FBgn0266557; Expressed in brain and 28 other cell types or tissues.
DR ExpressionAtlas; M9NDB7; baseline and differential.
DR GO; GO:0000785; C:chromatin; IBA:GO_Central.
DR GO; GO:0005654; C:nucleoplasm; HDA:FlyBase.
DR GO; GO:0005634; C:nucleus; IDA:FlyBase.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IBA:GO_Central.
DR GO; GO:0008094; F:ATP-dependent activity, acting on DNA; ISS:FlyBase.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IBA:GO_Central.
DR GO; GO:0003682; F:chromatin binding; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; IBA:GO_Central.
DR GO; GO:0042393; F:histone binding; IBA:GO_Central.
DR GO; GO:0007411; P:axon guidance; IMP:FlyBase.
DR GO; GO:0007350; P:blastoderm segmentation; IMP:FlyBase.
DR GO; GO:0006338; P:chromatin remodeling; IBA:GO_Central.
DR GO; GO:0008340; P:determination of adult lifespan; IMP:FlyBase.
DR GO; GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase.
DR GO; GO:0040011; P:locomotion; IMP:FlyBase.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IMP:FlyBase.
DR GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IMP:FlyBase.
DR GO; GO:0016322; P:neuron remodeling; IMP:FlyBase.
DR GO; GO:1903688; P:positive regulation of border follicle cell migration; IMP:FlyBase.
DR GO; GO:0046622; P:positive regulation of organ growth; IMP:FlyBase.
DR GO; GO:1902685; P:positive regulation of receptor localization to synapse; IMP:FlyBase.
DR GO; GO:0010468; P:regulation of gene expression; IBA:GO_Central.
DR GO; GO:0008582; P:regulation of synaptic assembly at neuromuscular junction; IMP:FlyBase.
DR GO; GO:0007379; P:segment specification; IMP:FlyBase.
DR GO; GO:0007614; P:short-term memory; IMP:FlyBase.
DR CDD; cd18668; CD1_tandem_CHD5-9_like; 1.
DR CDD; cd18663; CD2_tandem_CHD5-9_like; 1.
DR CDD; cd17995; DEXHc_CHD6_7_8_9; 1.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 2.40.50.40; -; 2.
DR Gene3D; 3.40.5.120; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR006576; BRK_domain.
DR InterPro; IPR037259; BRK_sf.
DR InterPro; IPR016197; Chromo-like_dom_sf.
DR InterPro; IPR000953; Chromo/chromo_shadow_dom.
DR InterPro; IPR023780; Chromo_domain.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR PANTHER; PTHR45623; CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED; 1.
DR PANTHER; PTHR45623:SF11; KISMET, ISOFORM C; 1.
DR Pfam; PF07533; BRK; 1.
DR Pfam; PF00385; Chromo; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR SMART; SM00592; BRK; 1.
DR SMART; SM00298; CHROMO; 2.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF160481; BRK domain-like; 1.
DR SUPFAM; SSF54160; Chromo domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50013; CHROMO_2; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 1: Evidence at protein level;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Proteomics identification {ECO:0007829|PeptideAtlas:M9NDB7};
KW Reference proteome {ECO:0000313|Proteomes:UP000000803};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1940..2006
FT /note="Chromo"
FT /evidence="ECO:0000259|PROSITE:PS50013"
FT DOMAIN 2041..2215
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 2354..2505
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 30..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 121..490
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 509..676
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 698..753
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 765..835
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 851..914
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 980..1003
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1035..1069
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1182..1230
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1292..1631
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1658..1871
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2625..2670
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2773..2832
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2907..2968
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3041..3063
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3412..3651
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3776..3811
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3854..3878
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3914..3974
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4068..4144
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4241..4308
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4351..4421
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4531..4571
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4651..4682
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4694..4728
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4768..4804
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4830..4850
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4909..4935
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5029..5050
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5089..5113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5143..5252
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..58
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 126..218
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 295..338
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 354..403
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 405..437
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 438..464
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 529..545
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 552..676
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 981..1003
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1055..1069
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1188..1207
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1313..1335
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1405..1422
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1443..1466
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1487..1502
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1514..1540
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1557..1573
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1595..1631
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2790..2822
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2907..2932
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2945..2959
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3412..3534
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3562..3620
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3919..3954
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4074..4143
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4252..4301
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4534..4571
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4912..4926
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5089..5103
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5158..5181
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5214..5228
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5229..5246
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 5252 AA; 566086 MW; C738C069B0FE5261 CRC64;
MDGNAQNMFH GNHQGDPYYR YDAAAAAAAA AAANPRAMGP PGGYPPRHRP PHPLQQQPQY
PSYQPTAENL YGLGAADHQA AMGLGVGVGV GAGMGDLSGW GAAPSVPGQA AAYPGAGLGA
YGHPQAAPPS QQQRQSNASA YRQHMPAYGQ QDQQKLASYG AQQSMMAGYG SLAPQQQQQQ
QPPTPQQQQQ AQQVQQQAQQ QQQQQQQQSQ QQARLPQHYP QAPGQHPLYP GVGAPTVQAG
QPPTPQAYAH SPYGSPMQHQ PSRGAPQHVG YGHTGLDQAS AYGQHVPGGA PPGHHLSAQQ
QQAAQQLGAH QQQQLQSQQQ QQAQQQQPHV SLMQQQQLPG AGLPPPHMGM PPSYGSHHQQ
QQQQQQTQQQ QQQSAPPYMS SSKHQQAAAQ LNSSPQYRAP FPQLSPQMSP RPPTMSPHPQ
MSPRPVGVSP AKPPPPQQQQ QQTQAQQPQQ VVSNQPSQHS IQGMVGLPSP RPQPPTSGAG
GAGAKGPAPV AAPVNTLQAL EQMVMPSQAL GLPPMDYPSA YRSAVGPRMP ASPQQQQQQH
QQWGAAHGAQ HLAALQQQQA QQQQQQVQQQ QQAPPQQQQQ AAMLQAQQQH HQQQLSMYGQ
PMGQQPQTAQ QQVVPPVTSQ PPVVAASQQQ QQQQHQQQSL NDQLQHSIND IVGGGNSSGA
TGGAQNQHQQ QPQLAAMSSP LHQQNLPNMH HLIQPTMETT QPTQQQQQTS QQQQQPQQPQ
ATLTSPHHQQ MQHQSPIHQQ QQSPHHQQHL PSYNQSQQQF DPFANILGDN QPAASQQTMS
PAHVSSPVPA QMQQQQHQTQ QQPSQQVPQS QQQQVSQPQQ QTQQQQPSTP SHHLSSILNE
TANSNDSSTL AVAANDSNNS SSNSSTNSIV NNQPTSVHDS NSQSSINSSS NNQQQLLMDN
TNSHGGNSES AQNAGVDVGL FDNNSMSSNS AAVAAVASNA ASAAAALLDS NSQSSNAEFE
KNQSEGEGLG VVEGVIANET DLPQDENSVS KTQDITLSTE LPTIQDDLQE KPTAEMEQTQ
LGQSLGDLSK SLLEEPKTVE ESGEDKSQSA PGVAPPADPI IPVTQPPQQQ MPPIGMPMHP
IAPGYEAQAQ GQGHMPPMMP PYGGAPGMYP PYPMLHQQEI AALQQQIQEL YCMPPGHELQ
HQDKLMRMQE RLNLLTQHEV NDQCAGGPQC LLFQNVPPMY GPPGNPLLNQ QMVESPQVSS
TTGRGRGKSA NKPRKPRAKK GEKAQVGQQQ DLMDISGNVA MGAANAVSSI PTTQLPVSED
CVTQGAGDTS VVGMLEYSEG MGDLSQDVHS ANELDTSTDG SGKKKKPRKP RTPKDPNKPP
RDRTPKAKKP KDPNDPNSTE TPAAVKKRAG ASKRRKQYGE DGAEQTGEGS EVEDNKPLVP
KAGSADGEAE TTSGGTGVDG ESPDYDDIPV SKIPRGSNED EKEAEAGDET VDSVPDSAGD
PASTPSRRDR KRSTARSRRN ANSEEGGSAR KNRGSLSAKA LKKRRNRGRI VPESDGEDDT
LDRTPPPSPP PDSEMDSNKR RSSRNTQRKK YIDDVMLRFS DDENSLLVAS PVKKDKKPSA
NASNSNAGSD VEKTEPQSGA EGDAAQEVGE EKSNLPLDES SQLEASSSTS AVAEKERQIS
TDAANAAMSS KPNYVYINTG DEDSMVVQLV LAMRMGKREL ILDKPKEKAP EPKQDEEKSE
LDEATTDKPE GDEKFKTEGE SKKDLTDSEE TKLESSAMEV DSKEESEPDD SKKSDEDNKD
KDKMEVDDEV GKSDKESKPE EQSETVKTEE NSKAIEEDKS STVLTADHAK EPETVLEKME
VDEKANDDQS AVSKAEGSDE KSTDDSNPEE ATTEKNKESL EIEGEKERVK EGEESVKKEN
DEKTEADMEN KPEPVFIDVE EYFVKYRNFS YLHCEWRTEE ELLKGDRRVA AKIRRFQQKQ
SQQLNIFENI EDEPFNQDFT EVDRVLDMSV HTDETSGETT KHYLVKWKSL PYEDCTWELE
EDVDNDKIEQ YLRFNKIPQR SEWKSKKRPH PELWKKLEKT PVYKGGNSLR PYQLEGLNWL
KFSWYNTHNC ILADEMGLGK TIQSLTFVHS VYEYGIRGPF LVIAPLSTIP NWQREFEGWT
DMNVVVYHGS VTSKQMIQDY EYYYKTESGK VLKEPIKFNV LITTFEMIVT DYMDLKAFNW
RLCVIDEAHR LKNRNCKLLE GLRQLNLEHR VLLSGTPLQN NISELFSLLN FLEPSQFSSQ
EEFMSEFGSL RTEEEVNKLQ ALLKPMMLRR LKDDVEKSLA PKEETIIEVE LTNIQKKYYR
GILEQNFSFL KKGTTSANIP NLMNTMMELR KCCIHPYLLN GAEEQIQYDF KSQHGEDPES
YYKNLILSAG KMVLIDKLLP KLKANGHRVL IFSQMVRCLD ILEDYLVYRK YPFERIDGRI
RGNLRQEAID RYSKPGSDRF VFLLCTKAGG LGINLTAADT VIIYDSDWNP QNDLQAQARC
HRIGQRKMVK IYRLLCRNTY EREMFDKASM KLGLDKAVLQ SMNTQGSKDG NNKQLSKKEI
EDLLKKGAYG AVMDDDNAGD KFCEEDIDSI LKRRTQVITM ESEKGSTFSK ASFAASGNRS
DITIDDPDFW TKWAKKVDID PDACERDETE DLVLSEPRRR TQIKRYGHED VMELNSEESS
NENSDEEGGI GLRSRRRKEK RDRAREKKGN DEYIPRERDA LAALGLEEIQ YGNWAKSECF
KVEKGLLSFG WGRWSELLEL GQFKRGWRDV DVEDCARIIL LYCLQVYKGD EKIKTFIWDL
ITPTEDGEVQ KISRDHSGLH NLVPRGRNGG KSNKESTGVS TPAPGSASGS NSGNTTPAHK
SSALDGSDKD SGGINASAVA AAVTSIHDPN HWSKKEKYDA DAYLEGAYKK HLGRHANKVL
LRVRMLYYIQ HEVIGDFVQQ IKDNTPIRNE DDANSKHDDG DEVDDDGTTT TKDSDSTKLT
GGDNKDSLLD PERPSSSGLD EEESVAGSYP PTVAAVEDAT TMWPSMQDLN TRLRRVITAY
QRNYKKEELK LQQKAKLQAL VSSTPPLSVP TTPTLQSMQM QLQSGSGSGG SGIGSSAQHD
ASGRSLQALM QSQGASTSAA AAAAASSAGG SCSGSGQVGM GGAGVMPAMP TAADISLMLS
ILNTTDVNQL ANLDINKLAM YLVSMNNKME RQGKMELAAK ERESQRLQLI PKKWNRREEY
EFLRVLTGYG VDLHVSTPMA SSNGSSLSPD WTKFKQMAHL ERKSDETLTD YYKVFVAMCK
RQAGLKLSES ERGLEGIIEE IEKEHAKLIL DRLEVLAKLR EVARNPMLEE RLKLCTKNAD
TPDWWEPGRH DKELITAVLK HGLYRSETFI FNDPNFSFGE SEKRFIRELE AQIQRTIKLE
AFNAEKAEKL AAAEKDAATE KAAATEKAAA EKAASVKNEV IDLDDELMTN ESVIKKESPV
TPIKEEIKSE ESPEKHDTAD NLEDKNSDAE ESTKIKGKED FNPETTEKEA LDESTNLNKD
KSSTETLVPE IEDSKPSEDK MEVEELPVAE NGEKEGSPEK CSDAEDKKFS EEKPSSPAVP
DGKVSEMEAD EAAPNTEENC SGDSESPEKE CEDKVVEKVE EEKGENSYEK AEEQKEETEK
LEKSSIESEP SEKSETVLEP EVAVPKKSTG DQDILDLVAG PSDPDDDEVM KEKEKAVEEE
CKKQAAELKA RFPDLEVIQP ATVKQQKLEK PKLEMCMIRW FKDFALERRI AHIVACVESG
NWPVDSKYSA FATCKGATDL SIALHESIPH LSSLERRSTT PDVITITTDQ GVTKHLQTSH
MQQVASSASA ASTSSGVPQV TQSKPSSSNS LPGLDAKSIN AAVAAAVAAA AAGGNATSLS
SLLPGMSLSA ATGSSAGGVS GLSVPSAGSG VGKKRKRHIA IDVETERAKL HALLNSSTMA
PKDWESEIAN MEALSGSSGR GRGGNSSASS GMQPPPAHQH ASLSRQSSGQ FSKPAVPAMK
TPPPSMGAPM DLSSSLPKMN MTEMLKSASS SGAIDLSEVQ DFSMPSKKSS VHAALSSAFP
SMGNKSKLDD TLNKLMKKNN CTIEEPVIGK EKKRKKLDEI VLGLSAAKEQ KTFPDPSLPS
SKKPQIPPSV SVTPANLQSS SNQQSNQKPF TITVTTVPGK SKSGSSNSGS GTGGSSSASG
GGAGGSGLSA LQNMAMGGLS SKDSLNALLA QTMATDPQTF LKQQQKMMQF LPPAQRKAYE
NMLAEMEQAM KISSKFSTNS PHDVKVNKWL SDMTSPLGDQ LSIDYVGGGG ASGSGSGNSR
RSNRQQGNSQ QSSSAAQLQK QQQQQQQQQQ QQQQHSMPGP QNLTGEEPVP VINKQTGKRL
GGNKAPQLKR LMQWLTENPN YEVDPKWLEQ MQNPMSTPSP RPASMESGYG SSAVKSHGGR
PLSNLSSTSS SSHTQQQSSA AQSQAGGNSG SSKKNSRQQT AASAALDQAA LQFGSLAGLN
PSLLANLPGL GAFDPKNPLA AFDPKNPLLS MSFGGMPGMG NIPGLGNLNN MNLFASLAGM
GGLGNLAGMD TQSLAALMAA AGPTLGGLTG ASGGAGSGKS QAQSQSSATS SSSSASKKKQ
QQQQQQAQNE AAQLAAAISA STGGSGASGG KNAAASASQL AAGFPFLFPN PSLLYPPMGL
GGLNPYSLGS SGLGSAYDQL AQQYNLLNGA TSSASNTSST QSKSHQSQSK SSQSRNTTAS
ANSAASLMNA MASMGGGAST VTTPSTSASG SGRGRQSSSR NQSQTTPTAA DMAQLSSLLM
PGADPHLLES LSRMSNMDLA QATRLMSSLG MPPLSGTPSS SGGGNTSTSK RSSQAANEAN
VQAKEQQKWL ESLARGALPT DLAALQAFSQ GKMPSTSGSN TGTSTSSSKS SKAAATAAAA
QLPQIPGMSS DFPQAFLAEM AAQAMAAAGG SLPLSGPGSL ASLAGLTGGS AGGGGSSASG
STSHSSSKRQ REQDAFKQQM DYYTKTLGLG SGISLIPTSS AGGSSASSSA ANAAAAAYAA
ALDAEQQHQQ QQKALSKRAR GDLHPTKEEL AALAAGLPLN LGASMSSIEK SLRGGSSSSS
SSTPAPMTAE QDKVTLTPLN ASGGGSGSSS SSAAAAGLAA NLPSQTTITI APPISSGAST
SSERSERSES RISLTITNAA DAAKLPPPYE EADELIIQPI LKKPTAANPG SSHGGSVDDL
DTAENTSAAN LSGSSSSSAA AAAAAAAEEN RRSSNRLKRP RSGNEQGSGS VEGQPPEKRR
ELRSTRHTRS SADASTLNLS TGSESGAEER NE
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