ID M9SH51_METAX Unreviewed; 443 AA.
AC M9SH51;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Exodeoxyribonuclease VII large subunit {ECO:0000313|EMBL:AGI85478.1};
DE EC=3.1.11.6 {ECO:0000313|EMBL:AGI85478.1};
GN ORFNames=MMALV_07400 {ECO:0000313|EMBL:AGI85478.1};
OS Methanomethylophilus alvi (strain Mx1201).
OC Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
OC Methanomassiliicoccales; Methanomethylophilaceae; Methanomethylophilus.
OX NCBI_TaxID=1236689 {ECO:0000313|EMBL:AGI85478.1, ECO:0000313|Proteomes:UP000012672};
RN [1] {ECO:0000313|EMBL:AGI85478.1, ECO:0000313|Proteomes:UP000012672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Mx1201 {ECO:0000313|EMBL:AGI85478.1,
RC ECO:0000313|Proteomes:UP000012672};
RX PubMed=23209209; DOI=10.1128/JB.01867-12;
RA Borrel G., Harris H.M., Tottey W., Mihajlovski A., Parisot N.,
RA Peyretaillade E., Peyret P., Gribaldo S., O'Toole P.W., Brugere J.F.;
RT "Genome sequence of 'Candidatus Methanomethylophilus alvus' Mx1201, a
RT methanogenic archaeon from the human gut belonging to a seventh order of
RT methanogens.";
RL J. Bacteriol. 194:6944-6945(2012).
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DR EMBL; CP004049; AGI85478.1; -; Genomic_DNA.
DR RefSeq; WP_015504625.1; NC_020913.1.
DR AlphaFoldDB; M9SH51; -.
DR STRING; 1236689.MMALV_07400; -.
DR GeneID; 41321529; -.
DR KEGG; max:MMALV_07400; -.
DR eggNOG; arCOG04513; Archaea.
DR HOGENOM; CLU_023625_3_1_2; -.
DR InParanoid; M9SH51; -.
DR OrthoDB; 60263at2157; -.
DR Proteomes; UP000012672; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0009318; C:exodeoxyribonuclease VII complex; IEA:InterPro.
DR GO; GO:0008855; F:exodeoxyribonuclease VII activity; IEA:UniProtKB-EC.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006308; P:DNA catabolic process; IEA:InterPro.
DR CDD; cd04489; ExoVII_LU_OBF; 1.
DR HAMAP; MF_00378; Exonuc_7_L; 1.
DR InterPro; IPR003753; Exonuc_VII_L.
DR InterPro; IPR020579; Exonuc_VII_lsu_C.
DR InterPro; IPR025824; OB-fold_nuc-bd_dom.
DR NCBIfam; TIGR00237; xseA; 1.
DR PANTHER; PTHR30008; EXODEOXYRIBONUCLEASE 7 LARGE SUBUNIT; 1.
DR PANTHER; PTHR30008:SF0; EXODEOXYRIBONUCLEASE 7 LARGE SUBUNIT; 1.
DR Pfam; PF02601; Exonuc_VII_L; 1.
DR Pfam; PF13742; tRNA_anti_2; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:AGI85478.1};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Reference proteome {ECO:0000313|Proteomes:UP000012672}.
FT DOMAIN 6..99
FT /note="OB-fold nucleic acid binding"
FT /evidence="ECO:0000259|Pfam:PF13742"
FT DOMAIN 123..434
FT /note="Exonuclease VII large subunit C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02601"
SQ SEQUENCE 443 AA; 49050 MW; 8CF1B58A24A51722 CRC64;
MSERVTVTEL NTRVKEVLNN TKELNDLWLL GEISNLKKYT SGHYYFTIKD PGSEIRAVMF
RSSRARIDFE PSDSMKIEAY GHLDMYVERG SYQFIVESMK RSGIGELYLK YEALKKKLDG
EGLFRQDRKR KIPQYPKTIG VVTSPTGAVI HDIITTTGRL YPVDILLAPA QVQGDGAWKT
IVAGIELLNR VGVDVIIVGR GGGSLEDLWP FNEEPVARAI AASKVPVISS VGHETDFTIA
DFVADVRAAT PTAAAQIAVR DKGEIRRQLE DFTVRMNKAL TAVTERMRGR FMVVDSKLSP
QKARDRVDML LMKLDDMSSR MAGALSKKTM EMHRRLSSAD ARLVPALGSV VSGKKMSSEA
VFSRIGPAIS TMMGTKRAYL ERTSARLDAL SPYSVLERGY SFVAGPDGRA VTSVKGLHAG
SVITVRMRDG KAEAEIKDKE EFE
//
