ID M9X310_MEIRD Unreviewed; 468 AA.
AC M9X310;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE SubName: Full=Metal dependent phosphohydrolase {ECO:0000313|EMBL:AGK03717.1};
GN ORFNames=K649_02065 {ECO:0000313|EMBL:AGK03717.1};
OS Meiothermus ruber (strain ATCC 35948 / DSM 1279 / VKM B-1258 / 21) (Thermus
OS ruber).
OC Bacteria; Deinococcota; Deinococci; Thermales; Thermaceae; Meiothermus.
OX NCBI_TaxID=504728 {ECO:0000313|EMBL:AGK03717.1, ECO:0000313|Proteomes:UP000013026};
RN [1] {ECO:0000313|EMBL:AGK03717.1, ECO:0000313|Proteomes:UP000013026}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35948 / DSM 1279 / VKM B-1258 / 21
RC {ECO:0000313|Proteomes:UP000013026};
RA Chin J., Alexander D.H., Marks P., Korlach J., Clum A., Copeland A.;
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP005385; AGK03717.1; -; Genomic_DNA.
DR AlphaFoldDB; M9X310; -.
DR STRING; 504728.K649_02065; -.
DR KEGG; mre:K649_02065; -.
DR PATRIC; fig|504728.9.peg.428; -.
DR eggNOG; COG3437; Bacteria.
DR Proteomes; UP000013026; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd00077; HDc; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR037522; HD_GYP_dom.
DR InterPro; IPR006675; HDIG_dom.
DR InterPro; IPR048430; MASE9.
DR NCBIfam; TIGR00277; HDIG; 1.
DR PANTHER; PTHR45228:SF1; CYCLIC DI-GMP PHOSPHODIESTERASE TM_0186; 1.
DR PANTHER; PTHR45228; CYCLIC DI-GMP PHOSPHODIESTERASE TM_0186-RELATED; 1.
DR Pfam; PF13487; HD_5; 1.
DR Pfam; PF20972; MASE9; 1.
DR SMART; SM00471; HDc; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR PROSITE; PS51831; HD; 1.
DR PROSITE; PS51832; HD_GYP; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:AGK03717.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 69..94
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 142..167
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 179..198
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 204..223
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 234..431
FT /note="HD-GYP"
FT /evidence="ECO:0000259|PROSITE:PS51832"
FT DOMAIN 256..380
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
FT REGION 444..468
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 447..468
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 468 AA; 52338 MW; 7EBA51C7C3D60E92 CRC64;
MKAPLPMPPL RVLLFLLVLL AAFAGLLYLL LPFGPYAPNP LDLVFWAALI VIARRAHVAL
PFSASMSHAF VVALAAVTLF PPWLAAGLVF VFSFNRDFGR PGYTWYKDLF NRTQSGLATS
LAGLAWGWAQ AHLGAHPYLQ EAAGILVASL VYFFVNVGSV TYVIHLASGA SLRKVWFENY
SWLWVSYLLQ APIGLLLAKA YQTPLIWGWG GFTVLFMMLL LYFSRFYWDE KVKIEAAFDD
TIEVLVAALD AKDPFTRLHS ERVAAIAGSI AKRMGFDEQD VKRITYAARI HDIGKVAIPD
SILLKPGKLT PEEFELIRSH PKKGLEVLHP MRSRLPQEVQ NVIVHHHERW DGSGYPSRLR
EEQIPLWARI VALADAYEAM TAGRAYSPAK TPQEALNEII MQAGRQFDPQ LVRHFEALWL
ESPIWKDRGE FLRRYTLPAH LSAWPSPSHS GPASATSPTS SSDRPGPS
//
