ID MINC_DEIRA Reviewed; 169 AA.
AC Q9RTK7;
DT 01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 27-MAR-2024, entry version 108.
DE RecName: Full=Probable septum site-determining protein MinC;
GN Name=minC; OrderedLocusNames=DR_1753;
OS Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / CCUG
OS 27074 / LMG 4051 / NBRC 15346 / NCIMB 9279 / VKM B-1422 / R1).
OC Bacteria; Deinococcota; Deinococci; Deinococcales; Deinococcaceae;
OC Deinococcus.
OX NCBI_TaxID=243230;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 13939 / DSM 20539 / JCM 16871 / CCUG 27074 / LMG 4051 / NBRC
RC 15346 / NCIMB 9279 / VKM B-1422 / R1;
RX PubMed=10567266; DOI=10.1126/science.286.5444.1571;
RA White O., Eisen J.A., Heidelberg J.F., Hickey E.K., Peterson J.D.,
RA Dodson R.J., Haft D.H., Gwinn M.L., Nelson W.C., Richardson D.L.,
RA Moffat K.S., Qin H., Jiang L., Pamphile W., Crosby M., Shen M.,
RA Vamathevan J.J., Lam P., McDonald L.A., Utterback T.R., Zalewski C.,
RA Makarova K.S., Aravind L., Daly M.J., Minton K.W., Fleischmann R.D.,
RA Ketchum K.A., Nelson K.E., Salzberg S.L., Smith H.O., Venter J.C.,
RA Fraser C.M.;
RT "Genome sequence of the radioresistant bacterium Deinococcus radiodurans
RT R1.";
RL Science 286:1571-1577(1999).
CC -!- FUNCTION: Cell division inhibitor that blocks the formation of polar Z
CC ring septums. Rapidly oscillates between the poles of the cell to
CC destabilize FtsZ filaments that have formed before they mature into
CC polar Z rings. Prevents FtsZ polymerization (By similarity).
CC {ECO:0000250}.
CC -!- SUBUNIT: Interacts with MinD and FtsZ. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the MinC family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AE000513; AAF11310.1; -; Genomic_DNA.
DR PIR; B75357; B75357.
DR RefSeq; NP_295476.1; NC_001263.1.
DR AlphaFoldDB; Q9RTK7; -.
DR SMR; Q9RTK7; -.
DR STRING; 243230.DR_1753; -.
DR PaxDb; 243230-DR_1753; -.
DR EnsemblBacteria; AAF11310; AAF11310; DR_1753.
DR KEGG; dra:DR_1753; -.
DR PATRIC; fig|243230.17.peg.1963; -.
DR eggNOG; COG0850; Bacteria.
DR HOGENOM; CLU_048711_2_0_0; -.
DR InParanoid; Q9RTK7; -.
DR OrthoDB; 9790810at2; -.
DR Proteomes; UP000002524; Chromosome I.
DR GO; GO:0000902; P:cell morphogenesis; IEA:InterPro.
DR GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR GO; GO:1901891; P:regulation of cell septum assembly; IEA:InterPro.
DR Gene3D; 2.160.20.70; -; 1.
DR InterPro; IPR016098; CAP/MinC_C.
DR InterPro; IPR013033; MinC.
DR InterPro; IPR036145; MinC_C_sf.
DR InterPro; IPR005526; Septum_form_inhib_MinC_C.
DR PANTHER; PTHR34108; SEPTUM SITE-DETERMINING PROTEIN MINC; 1.
DR PANTHER; PTHR34108:SF1; SEPTUM SITE-DETERMINING PROTEIN MINC; 1.
DR Pfam; PF03775; MinC_C; 1.
DR SUPFAM; SSF63848; Cell-division inhibitor MinC, C-terminal domain; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Reference proteome; Septation.
FT CHAIN 1..169
FT /note="Probable septum site-determining protein MinC"
FT /id="PRO_0000189032"
SQ SEQUENCE 169 AA; 17648 MW; 34B9319A5519E9FF CRC64;
MLTAQITVEI QGDTHPEAVE AALQGVREAG GTLGRVRAPR LTVNMPASVA AEPVTSAQTV
IVPHSVRAGF RGEYRGSVVV LGDVNPGAEL IAAGDVIVAG ALRGVVHAGY GGTHPDPIVW
ARPIASAQIR IGDAVARAPE GSSNMRRTDR TERAERAYLQ DGMIVIDVQ
//
