ID   MVP_INSV                Reviewed;         303 AA.
AC   Q01268;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 1.
DT   24-JAN-2024, entry version 65.
DE   RecName: Full=Movement protein;
DE            Short=MVP;
DE   AltName: Full=Non-structural movement protein;
DE            Short=NSm;
OS   Impatiens necrotic spot virus (INSV).
OC   Viruses; Riboviria; Orthornavirae; Negarnaviricota; Polyploviricotina;
OC   Ellioviricetes; Bunyavirales; Tospoviridae; Orthotospovirus;
OC   Orthotospovirus impatiensnecromaculae.
OX   NCBI_TaxID=11612;
OH   NCBI_TaxID=35939; Impatiens.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=1585644; DOI=10.1016/0042-6822(92)90528-w;
RA   Law M.D., Speck J., Moyer J.W.;
RT   "The M RNA of impatiens necrotic spot Tospovirus (Bunyaviridae) has an
RT   ambisense genomic organization.";
RL   Virology 188:732-741(1992).
CC   -!- FUNCTION: Viral movemement protein which is responsible for cell-to
CC       cell spread of viral genome. Increases the size exclusion limit (SEL)
CC       of plasmodesmata by forming tubules structures, thereby allowing viral
CC       ribonucleocapsids to spread directly to neighboring cells (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Oligomerizes to form tubule structures through host
CC       plasmodesma. Interacts with host A.thaliana At4g26020 protein, which is
CC       involved in antra- and inter-cellular trafficking (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host cell junction, host plasmodesma
CC       {ECO:0000250}. Note=Colocalizes with viral nucleocapsid aggregates in
CC       host cytoplasm.
CC   -!- SIMILARITY: Belongs to the tospovirus movement protein family.
CC       {ECO:0000305}.
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DR   EMBL; M74904; AAA46241.1; -; Genomic_RNA.
DR   PIR; A42544; A42544.
DR   RefSeq; NP_619690.1; NC_003616.1.
DR   GeneID; 956572; -.
DR   KEGG; vg:956572; -.
DR   OrthoDB; 5653at10239; -.
DR   Proteomes; UP000201303; Genome.
DR   GO; GO:0044219; C:host cell plasmodesma; IEA:UniProtKB-SubCell.
DR   GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR   InterPro; IPR006889; Bunya_NSM.
DR   InterPro; IPR000603; MPV.
DR   Pfam; PF00803; 3A; 1.
DR   PIRSF; PIRSF003959; NS-M_TospoV; 1.
PE   3: Inferred from homology;
KW   Host cell junction; Host-virus interaction; Transport;
KW   Viral movement protein.
FT   CHAIN           1..303
FT                   /note="Movement protein"
FT                   /id="PRO_0000221986"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          52..72
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   303 AA;  34105 MW;  BCD9CFD44E671C64 CRC64;
     MNSFFKSLRS SSSRELDHPR VTTTLSKQGA DIVVHNPSAN HNNKEVLQRA MDSSKGKILM
     NNTGTSSLGT YESDQISESE SYDLSARMIV DTNHHISSWK NDLFVGNGDK AATKIIKIHP
     TWDSRKQYMM ISRIVIWICP TIADPDGKLA VALIDPNKSV NARTVLKGQG SIKDPICFVF
     YLNWSIPKVN NTSENCVQLH LLCDQVYKKD VSFASVMYSW TKEFCDSPRA DLDKSCMIIP
     INRAIRAKSQ AFIEACKLII PKGNSEKQIR RQLAELSANL EKSVEEEENV TDNKIEISFD
     NEI
//