ID   N0E0M1_9MICO            Unreviewed;       364 AA.
AC   N0E0M1;
DT   26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 1.
DT   24-JAN-2024, entry version 31.
DE   SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:CCH70523.1};
DE            EC=1.3.1.12 {ECO:0000313|EMBL:CCH70523.1};
GN   ORFNames=BN10_590040 {ECO:0000313|EMBL:CCH70523.1};
OS   Phycicoccus elongatus Lp2.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Intrasporangiaceae;
OC   Phycicoccus.
OX   NCBI_TaxID=1193181 {ECO:0000313|EMBL:CCH70523.1, ECO:0000313|Proteomes:UP000013167};
RN   [1] {ECO:0000313|EMBL:CCH70523.1, ECO:0000313|Proteomes:UP000013167}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Lp2 {ECO:0000313|EMBL:CCH70523.1,
RC   ECO:0000313|Proteomes:UP000013167};
RX   PubMed=23178666; DOI=10.1038/ismej.2012.136;
RA   Kristiansen R., Nguyen H.T.T., Saunders A.M., Nielsen J.L., Wimmer R.,
RA   Le V.Q., McIlroy S.J., Petrovski S., Seviour R.J., Calteau A.,
RA   Nielsen K.L., Nielsen P.H.;
RT   "A metabolic model for members of the genus Tetrasphaera involved in
RT   enhanced biological phosphorus removal.";
RL   ISME J. 7:543-554(2013).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCH70523.1}.
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DR   EMBL; CAIZ01000129; CCH70523.1; -; Genomic_DNA.
DR   AlphaFoldDB; N0E0M1; -.
DR   STRING; 1193181.BN10_590040; -.
DR   eggNOG; COG0287; Bacteria.
DR   HOGENOM; CLU_055968_1_1_11; -.
DR   Proteomes; UP000013167; Unassembled WGS sequence.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR   GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR   GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR   Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR046825; PDH_C.
DR   InterPro; IPR046826; PDH_N.
DR   InterPro; IPR003099; Prephen_DH.
DR   PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR   Pfam; PF20463; PDH_C; 1.
DR   Pfam; PF02153; PDH_N; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS51176; PDH_ADH; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000313|EMBL:CCH70523.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000013167}.
FT   DOMAIN          4..288
FT                   /note="Prephenate/arogenate dehydrogenase"
FT                   /evidence="ECO:0000259|PROSITE:PS51176"
SQ   SEQUENCE   364 AA;  37072 MW;  C01F11B33E8147F9 CRC64;
     MTIQRVHVIG SGLIGSSLGL ALSRRGVHVT LEDISSTNAA LARDLGAGAL PEPLDTPDVV
     VAATPPDVTA GIVAGALDRW PSAVVTDVAS VKGSIVRALE QRGGGSGDLR RYCGSHPMAG
     RERSGAIAAR ADLFEGRPWV VTPTDATAAD ALATVQELAR LVGSAVTVLD PASHDAAVAA
     VSHVPQVVAS LAAARLRDLP EEAVGLAGQG LRDVTRIAAS DPGLWTQILA ANPRAVRDEL
     KAFSGDLEAV IGALGQLGDG DDAPGARGIL ATTIANGNAG HARIPGKHGA APTQYGVVRV
     LIPDEPGQLG RLFQDVGDTG TNIEEFIIDH GLGGQFGVGE VYVVPAAAEG LAEALQRKGW
     TLHA
//