ID N0E1E6_9MICO Unreviewed; 222 AA.
AC N0E1E6;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Acetyltransferases (The isoleucine patch superfamily) {ECO:0000313|EMBL:CCH70773.1};
DE EC=2.3.1.- {ECO:0000313|EMBL:CCH70773.1};
GN ORFNames=BN10_670018 {ECO:0000313|EMBL:CCH70773.1};
OS Phycicoccus elongatus Lp2.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Intrasporangiaceae;
OC Phycicoccus.
OX NCBI_TaxID=1193181 {ECO:0000313|EMBL:CCH70773.1, ECO:0000313|Proteomes:UP000013167};
RN [1] {ECO:0000313|EMBL:CCH70773.1, ECO:0000313|Proteomes:UP000013167}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lp2 {ECO:0000313|EMBL:CCH70773.1,
RC ECO:0000313|Proteomes:UP000013167};
RX PubMed=23178666; DOI=10.1038/ismej.2012.136;
RA Kristiansen R., Nguyen H.T.T., Saunders A.M., Nielsen J.L., Wimmer R.,
RA Le V.Q., McIlroy S.J., Petrovski S., Seviour R.J., Calteau A.,
RA Nielsen K.L., Nielsen P.H.;
RT "A metabolic model for members of the genus Tetrasphaera involved in
RT enhanced biological phosphorus removal.";
RL ISME J. 7:543-554(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCH70773.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CAIZ01000138; CCH70773.1; -; Genomic_DNA.
DR RefSeq; WP_010850616.1; NZ_HF570956.1.
DR AlphaFoldDB; N0E1E6; -.
DR STRING; 1193181.BN10_670018; -.
DR eggNOG; COG0110; Bacteria.
DR HOGENOM; CLU_081811_1_1_11; -.
DR OrthoDB; 708224at2; -.
DR Proteomes; UP000013167; Unassembled WGS sequence.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR CDD; cd03360; LbH_AT_putative; 1.
DR Gene3D; 3.40.50.20; -; 1.
DR Gene3D; 2.160.10.10; Hexapeptide repeat proteins; 1.
DR InterPro; IPR020019; AcTrfase_PglD-like.
DR InterPro; IPR018357; Hexapep_transf_CS.
DR InterPro; IPR041561; PglD_N.
DR InterPro; IPR011004; Trimer_LpxA-like_sf.
DR NCBIfam; TIGR03570; NeuD_NnaD; 1.
DR PANTHER; PTHR43300; ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR43300:SF7; UDP-N-ACETYLBACILLOSAMINE N-ACETYLTRANSFERASE; 1.
DR Pfam; PF17836; PglD_N; 1.
DR SUPFAM; SSF51161; Trimeric LpxA-like enzymes; 1.
DR PROSITE; PS00101; HEXAPEP_TRANSFERASES; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000313|EMBL:CCH70773.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000013167};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:CCH70773.1}.
FT DOMAIN 11..97
FT /note="PglD N-terminal"
FT /evidence="ECO:0000259|Pfam:PF17836"
FT ACT_SITE 152
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR620019-1"
FT BINDING 85
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR620019-2"
FT SITE 153
FT /note="Increases basicity of active site His"
FT /evidence="ECO:0000256|PIRSR:PIRSR620019-1"
SQ SEQUENCE 222 AA; 22423 MW; 9B5768DC964C6FE8 CRC64;
MTSPDGFGLE RVVVVGASGF GRECLDVLEA MAAAGSPVEV VGVVDDGPSE LNMERLAARG
VAYLGTVDEW LAGDAVTRRY VLGIGSPAVR RRLAARLEGT GARPFTAIHP SATFGARVAK
GEGAVVCAGV AVSTNVRLGR HVHLNPNVTV GHDAVLSDFV SVNPGAVISG EVVLGTAALV
GASATLLQNL WIGKGALIGA GAVVTRNVPA GVVVKGVPGT WD
//
