ID N1J5H7_BLUG1 Unreviewed; 1076 AA.
AC N1J5H7;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE SubName: Full=Elongation factor 2 {ECO:0000313|EMBL:CCU75100.1};
GN ORFNames=BGHDH14_bgh06316 {ECO:0000313|EMBL:CCU75100.1};
OS Blumeria graminis f. sp. hordei (strain DH14) (Barley powdery mildew)
OS (Oidium monilioides f. sp. hordei).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Erysiphales; Erysiphaceae; Blumeria; Blumeria hordei.
OX NCBI_TaxID=546991 {ECO:0000313|EMBL:CCU75100.1, ECO:0000313|Proteomes:UP000015441};
RN [1] {ECO:0000313|EMBL:CCU75100.1, ECO:0000313|Proteomes:UP000015441}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DH14 {ECO:0000313|EMBL:CCU75100.1};
RX PubMed=21148392; DOI=10.1126/science.1194573;
RA Spanu P.D., Abbott J.C., Amselem J., Burgis T.A., Soanes D.M., Stueber K.,
RA Ver Loren van Themaat E., Brown J.K.M., Butcher S.A., Gurr S.J.,
RA Lebrun M.-H., Ridout C.J., Schulze-Lefert P., Talbot N.J., Ahmadinejad N.,
RA Ametz C., Barton G.R., Benjdia M., Bidzinski P., Bindschedler L.V.,
RA Both M., Brewer M.T., Cadle-Davidson L., Cadle-Davidson M.M., Collemare J.,
RA Cramer R., Frenkel O., Godfrey D., Harriman J., Hoede C., King B.C.,
RA Klages S., Kleemann J., Knoll D., Koti P.S., Kreplak J., Lopez-Ruiz F.J.,
RA Lu X., Maekawa T., Mahanil S., Micali C., Milgroom M.G., Montana G.,
RA Noir S., O'Connell R.J., Oberhaensli S., Parlange F., Pedersen C.,
RA Quesneville H., Reinhardt R., Rott M., Sacristan S., Schmidt S.M.,
RA Schoen M., Skamnioti P., Sommer H., Stephens A., Takahara H.,
RA Thordal-Christensen H., Vigouroux M., Wessling R., Wicker T., Panstruga R.;
RT "Genome expansion and gene loss in powdery mildew fungi reveal tradeoffs in
RT extreme parasitism.";
RL Science 330:1543-1546(2010).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCU75100.1}.
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DR EMBL; CAUH01000963; CCU75100.1; -; Genomic_DNA.
DR AlphaFoldDB; N1J5H7; -.
DR STRING; 546991.N1J5H7; -.
DR eggNOG; KOG0467; Eukaryota.
DR HOGENOM; CLU_002794_3_1_1; -.
DR InParanoid; N1J5H7; -.
DR OrthoDB; 166721at2759; -.
DR Proteomes; UP000015441; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:EnsemblFungi.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:EnsemblFungi.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0042256; P:cytosolic ribosome assembly; IEA:EnsemblFungi.
DR CDD; cd01681; aeEF2_snRNP_like_IV; 1.
DR CDD; cd04096; eEF2_snRNP_like_C; 1.
DR CDD; cd01885; EF2; 1.
DR CDD; cd16268; EF2_II; 1.
DR CDD; cd16261; EF2_snRNP_III; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.240; -; 1.
DR Gene3D; 3.30.70.870; Elongation Factor G (Translational Gtpase), domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 3.90.1430.10; Yeast translation eEF2 (G' domain); 1.
DR InterPro; IPR041095; EFG_II.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR000640; EFG_V-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR42908:SF3; ELONGATION FACTOR-LIKE GTPASE 1; 1.
DR PANTHER; PTHR42908; TRANSLATION ELONGATION FACTOR-RELATED; 1.
DR Pfam; PF00679; EFG_C; 1.
DR Pfam; PF14492; EFG_III; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SMART; SM00838; EFG_C; 1.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Elongation factor {ECO:0000313|EMBL:CCU75100.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000313|EMBL:CCU75100.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000015441}.
FT DOMAIN 10..295
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 206..232
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 206..223
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1076 AA; 119399 MW; 165B16F348F3FFE2 CRC64;
MPVISPDKLI ALQQDPRCIR NDHGKTSLTD ALIATNGIIS SKLAGKIRYL DSRPDEQSRG
ITMQSSAISL HFSMWKRPAP EMDLEQADYL INLIDSPGHI DFSSEVSTAS RLCDGAVILI
DAVEGVCSQT ITVLRQAWVE RLKSLLVINK MDRLVTELKM TPSEAYTHLS KLLEQVNAVL
GSFFHGERME EDLNWREQVE KKIAETTSRE QFRSDKTKND ELNQTPLDSD NLGYEEKDDG
DLYFSPERNN VIFSSALDGW AFTVRQFASF YEKKLGINRK IMEKTLWGDF YLDPKSKKIL
SSKHLKGRNL KPMFCQLVLE QIWAVYRATI VGEREKGDQI MVEKIAKSLN ITIPTHVTRS
PNPRTLLATV FSSWIPLSTA LLVSVIESLP SPSESQKIRL PGLIDNSPGA AWVDPVLRNA
MINSISSAQS PAIAYVSKMI SVPQSELPEN KHRGKVLSPE EAREVARQKR AEIARARARE
IEEVSDPLNH FAVAIEGRGL SDSTTSDQLE RSDPEVLIGF ARIYSGTLSV GDSIYVLPPK
FSPEHLNTDS EPTKVTITAL YLLMGRELET LQSVPAGVIF GIGGLEGHIL KSGTICSQSV
GSVNLAGISM GSQPIVRVAL EPENPANLER MINGMKLLVQ SDPCAEYEQF ESGEHVLLTA
GELHLERCLT DLRERFANCE IQAGEPIVPF RETIVRADEM RHPMNRELGR GAMIATSASK
QATIKLSVRP LSADITQFLR KNSDSIRQFN FTSKSAGNVA SSSSISSTNI RSEIIEENED
SGTVSSLPLL EFKTRLGELL QSMRGPQEMY VDKIDKIMAF GPRRAGPNLL IDATAGAIFS
QSPQASTPEE VLAVKGSLQA RDFGDRISHA FQLATAQGPL CHEPVEGIVV FIEEVKLDPT
ADAESSVHEK LGRITSEVIK ITKSAIQQCF LDWSPRLCLA MYSCEIQAST EVLGRVYDVL
TRRRGRVLSE ALKEGTSYFT IQSVLPVAES FGFSDEIRKR TSGAASPQLI FQGYEILNED
PLWVPFTEDD LEDLGELADK ENVAKRYMDT VRKRKGLVVS GMKLVKDAEK QKTLKR
//
