ID N1J6B9_BLUG1 Unreviewed; 362 AA.
AC N1J6B9;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 28-JUN-2023, entry version 30.
DE RecName: Full=Pre-mRNA-splicing factor {ECO:0000256|RuleBase:RU369096};
GN ORFNames=BGHDH14_bgh02665 {ECO:0000313|EMBL:CCU75610.1};
OS Blumeria graminis f. sp. hordei (strain DH14) (Barley powdery mildew)
OS (Oidium monilioides f. sp. hordei).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Erysiphales; Erysiphaceae; Blumeria; Blumeria hordei.
OX NCBI_TaxID=546991 {ECO:0000313|EMBL:CCU75610.1, ECO:0000313|Proteomes:UP000015441};
RN [1] {ECO:0000313|EMBL:CCU75610.1, ECO:0000313|Proteomes:UP000015441}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DH14 {ECO:0000313|EMBL:CCU75610.1};
RX PubMed=21148392; DOI=10.1126/science.1194573;
RA Spanu P.D., Abbott J.C., Amselem J., Burgis T.A., Soanes D.M., Stueber K.,
RA Ver Loren van Themaat E., Brown J.K.M., Butcher S.A., Gurr S.J.,
RA Lebrun M.-H., Ridout C.J., Schulze-Lefert P., Talbot N.J., Ahmadinejad N.,
RA Ametz C., Barton G.R., Benjdia M., Bidzinski P., Bindschedler L.V.,
RA Both M., Brewer M.T., Cadle-Davidson L., Cadle-Davidson M.M., Collemare J.,
RA Cramer R., Frenkel O., Godfrey D., Harriman J., Hoede C., King B.C.,
RA Klages S., Kleemann J., Knoll D., Koti P.S., Kreplak J., Lopez-Ruiz F.J.,
RA Lu X., Maekawa T., Mahanil S., Micali C., Milgroom M.G., Montana G.,
RA Noir S., O'Connell R.J., Oberhaensli S., Parlange F., Pedersen C.,
RA Quesneville H., Reinhardt R., Rott M., Sacristan S., Schmidt S.M.,
RA Schoen M., Skamnioti P., Sommer H., Stephens A., Takahara H.,
RA Thordal-Christensen H., Vigouroux M., Wessling R., Wicker T., Panstruga R.;
RT "Genome expansion and gene loss in powdery mildew fungi reveal tradeoffs in
RT extreme parasitism.";
RL Science 330:1543-1546(2010).
CC -!- FUNCTION: Involved in spliceosome maturation and the first step of pre-
CC mRNA splicing. {ECO:0000256|RuleBase:RU369096}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU369096}.
CC -!- SIMILARITY: Belongs to the SPP2 family. {ECO:0000256|ARBA:ARBA00008576,
CC ECO:0000256|RuleBase:RU369096}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCU75610.1}.
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DR EMBL; CAUH01001508; CCU75610.1; -; Genomic_DNA.
DR AlphaFoldDB; N1J6B9; -.
DR STRING; 546991.N1J6B9; -.
DR eggNOG; ENOG502RZY8; Eukaryota.
DR HOGENOM; CLU_047291_0_0_1; -.
DR InParanoid; N1J6B9; -.
DR OrthoDB; 55448at2759; -.
DR Proteomes; UP000015441; Unassembled WGS sequence.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-UniRule.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:UniProtKB-UniRule.
DR InterPro; IPR045166; Spp2-like.
DR InterPro; IPR026822; Spp2/MOS2_G-patch.
DR PANTHER; PTHR15818; G PATCH AND KOW-CONTAINING; 1.
DR PANTHER; PTHR15818:SF2; G-PATCH DOMAIN AND KOW MOTIFS-CONTAINING PROTEIN; 1.
DR Pfam; PF12656; G-patch_2; 1.
PE 3: Inferred from homology;
KW mRNA processing {ECO:0000256|RuleBase:RU369096};
KW mRNA splicing {ECO:0000256|RuleBase:RU369096};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU369096};
KW Reference proteome {ECO:0000313|Proteomes:UP000015441};
KW Spliceosome {ECO:0000256|RuleBase:RU369096}.
FT DOMAIN 230..281
FT /note="Spp2/MOS2 G-patch"
FT /evidence="ECO:0000259|Pfam:PF12656"
FT REGION 1..68
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 297..362
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 46..60
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 299..362
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 362 AA; 40156 MW; C603568F0AA2971D CRC64;
MTSSAQTNDQ QSSKPVTGIK GFCLGGGTKV VTKLGKRRRL NAADESDSDN APNSYHEQHQ
AVSGFGEGGA IPAVTTAKKT TGPLVIARLE NRDWKSAARI RRHGEKLVTH TTAPSTAAIE
TKQDEAEIDS SGAEKIQWGL SVHHRRPERD IDTAGQQTTT PSIVTCPLMP ASSKAIQKSS
SLEEEALNAL LSHEEVVKRP ELIIATELAS ANPYTISEHD AFKQAVAAAP DVSSLEDYER
VPVEEFGAAL LRGMGWNGEK VERVRDIKRR QNLLGLGAKE LKEAEELGAW VNKSDTKRLN
AASARRHDGK SRPPKAGDYW REEEQRRERR EERSGGSYRR GGGYEKDYRR EAYQDRYRDR
KR
//
