ID N1J8K3_BLUG1 Unreviewed; 1366 AA.
AC N1J8K3;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Histidine kinase {ECO:0000313|EMBL:CCU76920.1};
GN ORFNames=BGHDH14_bgh01792 {ECO:0000313|EMBL:CCU76920.1};
OS Blumeria graminis f. sp. hordei (strain DH14) (Barley powdery mildew)
OS (Oidium monilioides f. sp. hordei).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Erysiphales; Erysiphaceae; Blumeria; Blumeria hordei.
OX NCBI_TaxID=546991 {ECO:0000313|EMBL:CCU76920.1, ECO:0000313|Proteomes:UP000015441};
RN [1] {ECO:0000313|EMBL:CCU76920.1, ECO:0000313|Proteomes:UP000015441}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DH14 {ECO:0000313|EMBL:CCU76920.1};
RX PubMed=21148392; DOI=10.1126/science.1194573;
RA Spanu P.D., Abbott J.C., Amselem J., Burgis T.A., Soanes D.M., Stueber K.,
RA Ver Loren van Themaat E., Brown J.K.M., Butcher S.A., Gurr S.J.,
RA Lebrun M.-H., Ridout C.J., Schulze-Lefert P., Talbot N.J., Ahmadinejad N.,
RA Ametz C., Barton G.R., Benjdia M., Bidzinski P., Bindschedler L.V.,
RA Both M., Brewer M.T., Cadle-Davidson L., Cadle-Davidson M.M., Collemare J.,
RA Cramer R., Frenkel O., Godfrey D., Harriman J., Hoede C., King B.C.,
RA Klages S., Kleemann J., Knoll D., Koti P.S., Kreplak J., Lopez-Ruiz F.J.,
RA Lu X., Maekawa T., Mahanil S., Micali C., Milgroom M.G., Montana G.,
RA Noir S., O'Connell R.J., Oberhaensli S., Parlange F., Pedersen C.,
RA Quesneville H., Reinhardt R., Rott M., Sacristan S., Schmidt S.M.,
RA Schoen M., Skamnioti P., Sommer H., Stephens A., Takahara H.,
RA Thordal-Christensen H., Vigouroux M., Wessling R., Wicker T., Panstruga R.;
RT "Genome expansion and gene loss in powdery mildew fungi reveal tradeoffs in
RT extreme parasitism.";
RL Science 330:1543-1546(2010).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCU76920.1}.
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DR EMBL; CAUH01003142; CCU76920.1; -; Genomic_DNA.
DR STRING; 546991.N1J8K3; -.
DR EnsemblFungi; BLGH_03174-mRNA-1; BLGH_03174-mRNA-1; BLGH_03174.
DR eggNOG; KOG0519; Eukaryota.
DR HOGENOM; CLU_002763_0_0_1; -.
DR InParanoid; N1J8K3; -.
DR OrthoDB; 12386at2759; -.
DR Proteomes; UP000015441; Unassembled WGS sequence.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR43719:SF11; HISTIDINE KINASE G7-RELATED; 1.
DR PANTHER; PTHR43719; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:CCU76920.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000015441};
KW Transferase {ECO:0000313|EMBL:CCU76920.1};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT DOMAIN 661..953
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 1213..1354
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT REGION 24..59
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 294..338
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 558..577
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 299..319
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 320..338
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 560..574
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 1265
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1366 AA; 151006 MW; 2FAAA26D4AF45F79 CRC64;
MSSPELSDGM SHIDGISDQT RARELYKYYQ PAAQPGPDDY STRQPNLDAP PSPEEVEQDH
DLKIDSNVSS SKISSPDTAL TVFCQLTAWR TGCQRAMIRF QSQASENQIM LIVRSLIDAE
TQYFVAESTK SMNLVDHTQH DPGDGLWMGC GSVSKAGRLC ERTIAVFPTC GETYPSFVVD
DLSKDERFNN LPFVTGPPFL KRYIGVPLIT KRGIPIGSLF VVDDKPGNGL SESNNRLMGT
MAKTVMRHFE LVREVEEHRR GIKMSRGLAS FVEGRAGLAE GILSEETILD PSRSCLFGTD
TAKHKDKTRD VDSKKTSKVS KFRTQSSGNP KDDRISNDSI APLELSSDEP EYSQTQTNIP
ESKAVDVDAS TRHSVTNTCM NTPPPGDDSE ETQIRALFSR AANIIQKSFE IKGGTIFYDA
RNGFSETISG PQTDINSTPQ SDRQHECDFT THVSQRKIVG ECEPADLSSS SIFTPCLNSI
DDASSQMSEY SSYINVTRNR RAEILGFSTQ NASSLKGDPV PGSQQLEAFR DRDLHALLRL
YPRGKLWTFS SDGTVIPDET LGGGNTNSSE SKLETPSPEV DDSFLSQYFP GVHQLLFDPL
WDAGRNRWLS CCFTWSTDPM RVLSRQKELS FMTAFGNSVM AEWARIDTEI ADQKKSDFIG
SISHELRSPL HGILASTEFL EEVTTGWEKQ LVETIESCGR TLLDTINHIL DFSKINHFES
NWRKSKRVKS RAGRSVSVKQ SELPMLKLFQ DTDISIICEE VIDSVFAGYI FQNTTAHSFD
QISDTQGKMS DSRLATDDPE RFTNCQKDAN GVVVILDINP QDYQVTTQPG ALRRLIMNLL
GNSLKYTSQG YVKVELDCSD MDDLVTSGPL GAAESVPQSM LTITVTDTGR GISPEFLRSK
LFTPFTQENT LSSGTGLGLS IVRAIVSLLE GKITIDSELG KGTKVKVCIP VLRRMPNNTA
ISVENTRPIM NKPQDAIIDL RSRVVGLPVK FYGFDCDVTD TILFEQLRLL KASISNFLVN
WYGMRIVPWE EKAQVIIANV ESLASISTIA CQDVSIHSRN PSIIALCSRS PATNRMFTLP
GTKCKIGYIV KPIGPVKLAK VISQTLGGAP VLQTPDLGSS ILDLTDLNHV FDELSVRVSD
DELCQSIIGP IDFLETSRLT APKQKLRATS ACRKENARLP VPLETSRNAY HLPTDSPVSK
QNVTSSPPHV VPRILVVDDN EINLQLLSTY LRRRAYPQID NAHNGLEAVQ KCEAMANSYD
IIFMDLTMPI LDGFGATRKI RAMEELRRMH VDLGEGSTSE PSSSKSGFVS AFIIAFTGRS
SIEDQNEALS CGIDLFMTKP VAFKEVGKIC DNWIANQIQA HAKIAT
//
