ID N1J9Q4_BLUG1 Unreviewed; 456 AA.
AC N1J9Q4;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 28-JUN-2023, entry version 33.
DE SubName: Full=Exopolyphosphatase {ECO:0000313|EMBL:CCU74612.1};
GN ORFNames=BGHDH14_bgh03428 {ECO:0000313|EMBL:CCU74612.1};
OS Blumeria graminis f. sp. hordei (strain DH14) (Barley powdery mildew)
OS (Oidium monilioides f. sp. hordei).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Erysiphales; Erysiphaceae; Blumeria; Blumeria hordei.
OX NCBI_TaxID=546991 {ECO:0000313|EMBL:CCU74612.1, ECO:0000313|Proteomes:UP000015441};
RN [1] {ECO:0000313|EMBL:CCU74612.1, ECO:0000313|Proteomes:UP000015441}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DH14 {ECO:0000313|EMBL:CCU74612.1};
RX PubMed=21148392; DOI=10.1126/science.1194573;
RA Spanu P.D., Abbott J.C., Amselem J., Burgis T.A., Soanes D.M., Stueber K.,
RA Ver Loren van Themaat E., Brown J.K.M., Butcher S.A., Gurr S.J.,
RA Lebrun M.-H., Ridout C.J., Schulze-Lefert P., Talbot N.J., Ahmadinejad N.,
RA Ametz C., Barton G.R., Benjdia M., Bidzinski P., Bindschedler L.V.,
RA Both M., Brewer M.T., Cadle-Davidson L., Cadle-Davidson M.M., Collemare J.,
RA Cramer R., Frenkel O., Godfrey D., Harriman J., Hoede C., King B.C.,
RA Klages S., Kleemann J., Knoll D., Koti P.S., Kreplak J., Lopez-Ruiz F.J.,
RA Lu X., Maekawa T., Mahanil S., Micali C., Milgroom M.G., Montana G.,
RA Noir S., O'Connell R.J., Oberhaensli S., Parlange F., Pedersen C.,
RA Quesneville H., Reinhardt R., Rott M., Sacristan S., Schmidt S.M.,
RA Schoen M., Skamnioti P., Sommer H., Stephens A., Takahara H.,
RA Thordal-Christensen H., Vigouroux M., Wessling R., Wicker T., Panstruga R.;
RT "Genome expansion and gene loss in powdery mildew fungi reveal tradeoffs in
RT extreme parasitism.";
RL Science 330:1543-1546(2010).
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCU74612.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CAUH01000456; CCU74612.1; -; Genomic_DNA.
DR AlphaFoldDB; N1J9Q4; -.
DR STRING; 546991.N1J9Q4; -.
DR EnsemblFungi; BLGH_04893-mRNA-1; BLGH_04893-mRNA-1; BLGH_04893.
DR eggNOG; KOG4129; Eukaryota.
DR HOGENOM; CLU_019358_1_0_1; -.
DR InParanoid; N1J9Q4; -.
DR OrthoDB; 1342473at2759; -.
DR Proteomes; UP000015441; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016462; F:pyrophosphatase activity; IEA:InterPro.
DR Gene3D; 3.10.310.20; DHHA2 domain; 1.
DR Gene3D; 3.90.1640.10; inorganic pyrophosphatase (n-terminal core); 1.
DR InterPro; IPR001667; DDH_dom.
DR InterPro; IPR038763; DHH_sf.
DR InterPro; IPR004097; DHHA2.
DR InterPro; IPR038222; DHHA2_dom_sf.
DR PANTHER; PTHR12112; BNIP - RELATED; 1.
DR PANTHER; PTHR12112:SF39; EG:152A3.5 PROTEIN (FBGN0003116_PN PROTEIN); 1.
DR Pfam; PF01368; DHH; 1.
DR Pfam; PF02833; DHHA2; 1.
DR SMART; SM01131; DHHA2; 1.
DR SUPFAM; SSF64182; DHH phosphoesterases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Manganese {ECO:0000256|ARBA:ARBA00023211};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000015441}.
FT DOMAIN 274..447
FT /note="DHHA2"
FT /evidence="ECO:0000259|SMART:SM01131"
SQ SEQUENCE 456 AA; 50836 MW; 1284F0C96FF594ED CRC64;
MNSPRASLPS FLSAAKHALT SYNVSQLQSL TFVIGNESAD LDSICSAVVW AYMLTYFTRS
KAASHRPTTL YVPLTNIPRA DFGLRPELNV ALHYAQLTPG QLISLNDLPV PLPPPKQTRW
LLVDHNSFTG SLGELYGSRV LGCIDHHDDE GRVPRGTRDG EGLEAEPRII QPSGSCASLV
IAWALERWKA ELTAQPQTNW STMNENEKQA WQKERQTIAA WDAQLARLAL APILIDSACL
TSSKTTSMDT NATNFLEWLI KYHEGTAYDR AAFYKELSIA KEDISSLSFL DALRKDYKQW
NEAEEVRNPN QPSCNLGIVA VVQPLSNLIS KAGNTTAFLS ILHSFSKERH LSILAIMTTS
HPEQQLQREL LVWGMDARGA MAVQWFETQT ALMLGLENWE ENSGRDVIAS TSLNEGLPGE
NSLRRVWNQR MIDNSRKQVA PLLRAAIRMN KGPPNI
//
