ID N1JE47_BLUG1 Unreviewed; 1532 AA.
AC N1JE47;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 24-JAN-2024, entry version 52.
DE SubName: Full=CCR4-NOT core complex subunit Not4 {ECO:0000313|EMBL:CCU78633.1};
GN ORFNames=BGHDH14_bgh04755 {ECO:0000313|EMBL:CCU78633.1};
OS Blumeria graminis f. sp. hordei (strain DH14) (Barley powdery mildew)
OS (Oidium monilioides f. sp. hordei).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Erysiphales; Erysiphaceae; Blumeria; Blumeria hordei.
OX NCBI_TaxID=546991 {ECO:0000313|EMBL:CCU78633.1, ECO:0000313|Proteomes:UP000015441};
RN [1] {ECO:0000313|EMBL:CCU78633.1, ECO:0000313|Proteomes:UP000015441}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DH14 {ECO:0000313|EMBL:CCU78633.1};
RX PubMed=21148392; DOI=10.1126/science.1194573;
RA Spanu P.D., Abbott J.C., Amselem J., Burgis T.A., Soanes D.M., Stueber K.,
RA Ver Loren van Themaat E., Brown J.K.M., Butcher S.A., Gurr S.J.,
RA Lebrun M.-H., Ridout C.J., Schulze-Lefert P., Talbot N.J., Ahmadinejad N.,
RA Ametz C., Barton G.R., Benjdia M., Bidzinski P., Bindschedler L.V.,
RA Both M., Brewer M.T., Cadle-Davidson L., Cadle-Davidson M.M., Collemare J.,
RA Cramer R., Frenkel O., Godfrey D., Harriman J., Hoede C., King B.C.,
RA Klages S., Kleemann J., Knoll D., Koti P.S., Kreplak J., Lopez-Ruiz F.J.,
RA Lu X., Maekawa T., Mahanil S., Micali C., Milgroom M.G., Montana G.,
RA Noir S., O'Connell R.J., Oberhaensli S., Parlange F., Pedersen C.,
RA Quesneville H., Reinhardt R., Rott M., Sacristan S., Schmidt S.M.,
RA Schoen M., Skamnioti P., Sommer H., Stephens A., Takahara H.,
RA Thordal-Christensen H., Vigouroux M., Wessling R., Wicker T., Panstruga R.;
RT "Genome expansion and gene loss in powdery mildew fungi reveal tradeoffs in
RT extreme parasitism.";
RL Science 330:1543-1546(2010).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCU78633.1}.
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DR EMBL; CAUH01004052; CCU78633.1; -; Genomic_DNA.
DR STRING; 546991.N1JE47; -.
DR EnsemblFungi; BLGH_04440-mRNA-1; BLGH_04440-mRNA-1; BLGH_04440.
DR eggNOG; KOG2068; Eukaryota.
DR HOGENOM; CLU_001793_0_0_1; -.
DR InParanoid; N1JE47; -.
DR OrthoDB; 1748at2759; -.
DR Proteomes; UP000015441; Unassembled WGS sequence.
DR GO; GO:0030014; C:CCR4-NOT complex; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR CDD; cd16618; mRING-HC-C4C4_CNOT4; 1.
DR CDD; cd12438; RRM_CNOT4; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR034261; CNOT4_RRM.
DR InterPro; IPR039780; Mot2.
DR InterPro; IPR039515; NOT4_mRING-HC-C4C4.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR003954; RRM_dom_euk.
DR InterPro; IPR000571; Znf_CCCH.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR12603; CCR4-NOT TRANSCRIPTION COMPLEX RELATED; 1.
DR PANTHER; PTHR12603:SF0; CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 4; 1.
DR Pfam; PF00076; RRM_1; 1.
DR Pfam; PF14570; zf-RING_4; 1.
DR SMART; SM00361; RRM_1; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 1.
DR PROSITE; PS50103; ZF_C3H1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00723};
KW Reference proteome {ECO:0000313|Proteomes:UP000015441};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00723};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00723}.
FT DOMAIN 15..58
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 120..208
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 205..232
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT ZN_FING 205..232
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT REGION 85..104
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 233..362
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 391..483
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 503..522
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 714..747
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 993..1016
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1031..1115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1141..1179
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 238..284
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 300..331
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 391..411
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 417..453
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 998..1016
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1031..1092
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1155..1176
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1532 AA; 167115 MW; D4FA36CF5BCFED73 CRC64;
MAPQDSFIDE DEDTCPLCVE EFDLSDKNFR PCPCGYQICQ FCFNNIKNNI NGLCPACRRP
YDEKTIEWKV VTPEEMAQFK ANIQKNAKKK QEQRQKEAQK REVESLNRKH LSGLRVVQKN
LVYVVGISPG IPEQEILSTL RGEKYFGQYG KIVKIVVSNK KQGDAGSNNQ SLGVYVTFAR
KEDAARCIAA VNGSQNGDRV LRAQLGTTKY CSAYLRNETC TNKNCMFLHE PGDNDDSYSR
QDLSSINSVN TQRPLSSMAT ASGANSRQPA PNQSTHTATA IPQTMMREGS KDELDSGDGS
ALPSSASWAN RGLPQRNRRD SHSTSIAASS PAISHALPAT AEVSEEPPAP VTQKLSEPAS
LSSSFITVQT NYNDTEDASV FKNILKAINS SDLSFPPPKS TEDSTNIYNS YPPLFDEHGG
QKRRAHKVHQ EDVELHIEQD SREFMKTIPE PPEDEEPESG SLQLGGEPED RDSSREGALP
SNFHNQQANT QLPIHRIANN NSSNLRLAQP NPHNSTNLNI SNGRTFTPLQ QQQHMHLMKS
NQQSELTEQY PSGIGNQLSL NSSLFQQGHG RQASRYNFAN DSSNSMKTSA NSKLMAQQSS
MMPSANFSQQ TGFYPQSIQG PPPGLKSSAT PPTNGSMFGQ NLGFSNSMSG NLFGGLQKEN
NSEMLRDIIR GRGNVGGNQT HDTGKREYMF SSFLHQYPPA STPAQGPGLA SIYGPQTGAF
HDFGQKQKKK GKKHRHANTS SSGGGGIVDL ADPSILQARM QHQQHSNSGV SQGLFGGQAQ
GQILPSLDEA RSSVDALVGD SVNEDYHRPS DAYGPISRSL TPLVPPGFSI PLVQASFTPQ
DRTSSKPSTL NVPIQASFVS RKVSSGSVTS YPQLTPIGLS QTTVAANTEI TSPLVKQDEK
PSAPVPLKPG KQPSTLHALH TEDFPALQSG KRKATTVRVA TPASLITIGK NPASSISQST
DKLDDFHTTP NAGIPATTKN NSKVTASVEF RKPSAFPPLP ASTTNASHHS SPRNIPKTLR
LTTVPKLDAL TTGATTPTHT SSVPASQTLP SRHHSLSSNI RLDRPGTPTS EITSDNISIT
STSFSRASSP PLTRVGSAPV RTATKSFQKK QRQAQKEKER AEIEAAVIVE PEVEIPPIMG
RKKKQKKERL HSNNGGLNLM ISQPITPGTA ENKSQAEKSI PKIEEQLEPS TKKLDTEVDS
LKMTNRLAIT KSQTKAKPHN IVKTEPTPVS LEVEKEEAEK SLPTPAIILQ ELVTSGVIKD
LSELYLLKNI TSSYKHLDML DKIDKVEISP KLVITPEDHD TLLAGKPVHK NAEGGFRIML
TPNGDCVRNL TEEEEIRYLY YQDQLVKDAG PTAFFSAKHS GQNGFTMIGG RAVPSGPPSF
FPVLKKANSC LDPVSKIQRD EALNYINQYV LPTLSSCAQY EKTLYTNEVQ GEMMRTDSVD
STLKTWGPDQ ASTLTATNDF YMSHSLNSEG VIENITTHFA IGEMRRQGNG SLLSLTDAEP
AMQLARKEVE GLEKKLNALI KKNRRILLGA GH
//
