ID N1JI46_BLUG1 Unreviewed; 990 AA.
AC N1JI46;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Ribonuclease R/mitotic control protein dis3 {ECO:0000313|EMBL:CCU81892.1};
GN ORFNames=BGHDH14_bgh01584 {ECO:0000313|EMBL:CCU81892.1};
OS Blumeria graminis f. sp. hordei (strain DH14) (Barley powdery mildew)
OS (Oidium monilioides f. sp. hordei).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Erysiphales; Erysiphaceae; Blumeria; Blumeria hordei.
OX NCBI_TaxID=546991 {ECO:0000313|EMBL:CCU81892.1, ECO:0000313|Proteomes:UP000015441};
RN [1] {ECO:0000313|EMBL:CCU81892.1, ECO:0000313|Proteomes:UP000015441}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DH14 {ECO:0000313|EMBL:CCU81892.1};
RX PubMed=21148392; DOI=10.1126/science.1194573;
RA Spanu P.D., Abbott J.C., Amselem J., Burgis T.A., Soanes D.M., Stueber K.,
RA Ver Loren van Themaat E., Brown J.K.M., Butcher S.A., Gurr S.J.,
RA Lebrun M.-H., Ridout C.J., Schulze-Lefert P., Talbot N.J., Ahmadinejad N.,
RA Ametz C., Barton G.R., Benjdia M., Bidzinski P., Bindschedler L.V.,
RA Both M., Brewer M.T., Cadle-Davidson L., Cadle-Davidson M.M., Collemare J.,
RA Cramer R., Frenkel O., Godfrey D., Harriman J., Hoede C., King B.C.,
RA Klages S., Kleemann J., Knoll D., Koti P.S., Kreplak J., Lopez-Ruiz F.J.,
RA Lu X., Maekawa T., Mahanil S., Micali C., Milgroom M.G., Montana G.,
RA Noir S., O'Connell R.J., Oberhaensli S., Parlange F., Pedersen C.,
RA Quesneville H., Reinhardt R., Rott M., Sacristan S., Schmidt S.M.,
RA Schoen M., Skamnioti P., Sommer H., Stephens A., Takahara H.,
RA Thordal-Christensen H., Vigouroux M., Wessling R., Wicker T., Panstruga R.;
RT "Genome expansion and gene loss in powdery mildew fungi reveal tradeoffs in
RT extreme parasitism.";
RL Science 330:1543-1546(2010).
CC -!- SIMILARITY: Belongs to the RNR ribonuclease family.
CC {ECO:0000256|ARBA:ARBA00005785, ECO:0000256|RuleBase:RU003901}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCU81892.1}.
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DR EMBL; CAUH01005548; CCU81892.1; -; Genomic_DNA.
DR AlphaFoldDB; N1JI46; -.
DR STRING; 546991.N1JI46; -.
DR EnsemblFungi; BLGH_03040-mRNA-1; BLGH_03040-mRNA-1; BLGH_03040.
DR eggNOG; KOG2102; Eukaryota.
DR HOGENOM; CLU_002333_5_0_1; -.
DR InParanoid; N1JI46; -.
DR OrthoDB; 945235at2759; -.
DR Proteomes; UP000015441; Unassembled WGS sequence.
DR GO; GO:0000177; C:cytoplasmic exosome (RNase complex); IEA:EnsemblFungi.
DR GO; GO:0000176; C:nuclear exosome (RNase complex); IEA:EnsemblFungi.
DR GO; GO:0005730; C:nucleolus; IEA:EnsemblFungi.
DR GO; GO:0000175; F:3'-5'-RNA exonuclease activity; IEA:EnsemblFungi.
DR GO; GO:0004521; F:RNA endonuclease activity; IEA:EnsemblFungi.
DR GO; GO:0000049; F:tRNA binding; IEA:EnsemblFungi.
DR GO; GO:0000467; P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR GO; GO:0006397; P:mRNA processing; IEA:EnsemblFungi.
DR GO; GO:0070651; P:nonfunctional rRNA decay; IEA:EnsemblFungi.
DR GO; GO:0071028; P:nuclear mRNA surveillance; IEA:EnsemblFungi.
DR GO; GO:0071039; P:nuclear polyadenylation-dependent CUT catabolic process; IEA:EnsemblFungi.
DR GO; GO:0071035; P:nuclear polyadenylation-dependent rRNA catabolic process; IEA:EnsemblFungi.
DR GO; GO:0071038; P:nuclear polyadenylation-dependent tRNA catabolic process; IEA:EnsemblFungi.
DR GO; GO:0043628; P:regulatory ncRNA 3'-end processing; IEA:EnsemblFungi.
DR CDD; cd09862; PIN_Rrp44-like; 1.
DR Gene3D; 2.40.50.690; -; 1.
DR Gene3D; 2.40.50.700; -; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR041505; Dis3_CSD2.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR InterPro; IPR002716; PIN_dom.
DR InterPro; IPR001900; RNase_II/R.
DR InterPro; IPR022966; RNase_II/R_CS.
DR InterPro; IPR033771; Rrp44_CSD1.
DR InterPro; IPR033770; RRP44_S1.
DR PANTHER; PTHR23355:SF35; EXOSOME COMPLEX EXONUCLEASE RRP44; 1.
DR PANTHER; PTHR23355; RIBONUCLEASE; 1.
DR Pfam; PF17849; OB_Dis3; 1.
DR Pfam; PF13638; PIN_4; 1.
DR Pfam; PF00773; RNB; 1.
DR Pfam; PF17216; Rrp44_CSD1; 1.
DR Pfam; PF17215; Rrp44_S1; 1.
DR SMART; SM00670; PINc; 1.
DR SMART; SM00955; RNB; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 3.
DR SUPFAM; SSF88723; PIN domain-like; 1.
DR PROSITE; PS01175; RIBONUCLEASE_II; 1.
PE 3: Inferred from homology;
KW Exosome {ECO:0000256|ARBA:ARBA00022835};
KW Reference proteome {ECO:0000313|Proteomes:UP000015441};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 85..206
FT /note="PIN"
FT /evidence="ECO:0000259|SMART:SM00670"
FT DOMAIN 518..851
FT /note="Ribonuclease II/R"
FT /evidence="ECO:0000259|SMART:SM00955"
SQ SEQUENCE 990 AA; 112803 MW; 5FD0D0D0BE4D4BBE CRC64;
MISLKNSLVS DPYTENISSK VYIRSTKSGK VQKIVRELYL RQDIPCSSRL CASCLDIAPR
NSRNNFAPFV LSTTPASTSV YKSGHYIVPD TNALLNALDL FESTSAFYDV IILQTVLEEL
RNRSLPLYNR LIGLTKSEEK RYYVFFNDFR LETYVLRDPG ESINDRNDRA VRRAVRWYDE
HLRQTVRGKA KVPSVVMLSN DKENLRKAKR DGIDAASLED YISSLENSDQ LLDMLSASKE
NLDIRQGSTP QNIYPEYFSL SKMMTGVKNG TLHQGIFNVS PYNYLEGSVH VPTFDKSLII
LGKENINRAI QGDVVVVEVL PRDQWKESST KIIEDATLNR YENADAEDKE AVVTEREKKA
LQEEVKMVHR NNLEGRPQPA AKVVGIIKRN WRQYVGHVDE SSVNQSLKLG RKQQTVFLIP
MDKKIPKIRI RTRQAGEIIG KRVLVTIDSW DRDSRYPVGH FVRSLGDLET KEAETEALLL
EFDVQYRPFP KSVLDCLPTQ GHNWVVPQNK EDPGWINRRD LRHLGICSID PIGCQDIDDA
LHARPLPNGN FEVGVHIADV SHFVKPNTAM DTEASVRGTT VYLVDKRIDM LPMLLGTDLC
SLKPYVERYA FSAIWEITPE ANIVKSEFTK SVIKSREAFS YEDAQTRVDD EMQQDDLTKS
MRILLMLSKK FNKKRMEAGA LSLSSPEVRV ETESETSDPI DIKTKKHLDT MSLVEEFMLL
ANTSVAAKIY EAFPQTAMLR RHGAPPKTNF EELANQLKVK RGLELRTSTS KELAESLDKC
VDAQEPFFNT MVRIIATRCM TSAEYFCSGT QAYPEFRHYG LASTIYTHFT SPIRRYADLV
AHRQLAAAIN YETLDASVRS RGKLETVCKN INIRHRNAQY AGRASIEYYV GQALKGRIVQ
EEGFIMKIFS NGFVVFVPRF GIENLIRLRD LAEIEPEGQF DAENYVLKTV GSREIEVELF
SKVIVRISDV KEEGTGKRKV KMELEKVIKR
//
