ID N1Q262_DOTSN Unreviewed; 638 AA.
AC N1Q262;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Adenosine deaminase domain-containing protein {ECO:0000259|Pfam:PF00962};
GN ORFNames=DOTSEDRAFT_68550 {ECO:0000313|EMBL:EME49792.1};
OS Dothistroma septosporum (strain NZE10 / CBS 128990) (Red band needle blight
OS fungus) (Mycosphaerella pini).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Dothistroma.
OX NCBI_TaxID=675120 {ECO:0000313|EMBL:EME49792.1, ECO:0000313|Proteomes:UP000016933};
RN [1] {ECO:0000313|Proteomes:UP000016933}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NZE10 / CBS 128990 {ECO:0000313|Proteomes:UP000016933};
RX PubMed=23209441; DOI=10.1371/journal.pgen.1003088;
RA de Wit P.J.G.M., van der Burgt A., Oekmen B., Stergiopoulos I.,
RA Abd-Elsalam K.A., Aerts A.L., Bahkali A.H., Beenen H.G., Chettri P.,
RA Cox M.P., Datema E., de Vries R.P., Dhillon B., Ganley A.R.,
RA Griffiths S.A., Guo Y., Hamelin R.C., Henrissat B., Kabir M.S.,
RA Jashni M.K., Kema G., Klaubauf S., Lapidus A., Levasseur A., Lindquist E.,
RA Mehrabi R., Ohm R.A., Owen T.J., Salamov A., Schwelm A., Schijlen E.,
RA Sun H., van den Burg H.A., van Ham R.C.H.J., Zhang S., Goodwin S.B.,
RA Grigoriev I.V., Collemare J., Bradshaw R.E.;
RT "The genomes of the fungal plant pathogens Cladosporium fulvum and
RT Dothistroma septosporum reveal adaptation to different hosts and lifestyles
RT but also signatures of common ancestry.";
RL PLoS Genet. 8:E1003088-E1003088(2012).
RN [2] {ECO:0000313|EMBL:EME49792.1, ECO:0000313|Proteomes:UP000016933}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NZE10 / CBS 128990 {ECO:0000313|Proteomes:UP000016933};
RX PubMed=23236275; DOI=10.1371/journal.ppat.1003037;
RA Ohm R.A., Feau N., Henrissat B., Schoch C.L., Horwitz B.A., Barry K.W.,
RA Condon B.J., Copeland A.C., Dhillon B., Glaser F., Hesse C.N., Kosti I.,
RA LaButti K., Lindquist E.A., Lucas S., Salamov A.A., Bradshaw R.E.,
RA Ciuffetti L., Hamelin R.C., Kema G.H.J., Lawrence C., Scott J.A.,
RA Spatafora J.W., Turgeon B.G., de Wit P.J.G.M., Zhong S., Goodwin S.B.,
RA Grigoriev I.V.;
RT "Diverse lifestyles and strategies of plant pathogenesis encoded in the
RT genomes of eighteen Dothideomycetes fungi.";
RL PLoS Pathog. 8:E1003037-E1003037(2012).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
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DR EMBL; KB446535; EME49792.1; -; Genomic_DNA.
DR AlphaFoldDB; N1Q262; -.
DR STRING; 675120.N1Q262; -.
DR EnsemblFungi; EME49792; EME49792; DOTSEDRAFT_68550.
DR eggNOG; KOG1097; Eukaryota.
DR HOGENOM; CLU_022829_1_0_1; -.
DR OMA; PGQHIFQ; -.
DR OrthoDB; 4403at2759; -.
DR Proteomes; UP000016933; Unassembled WGS sequence.
DR GO; GO:0019239; F:deaminase activity; IEA:InterPro.
DR Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR InterPro; IPR001365; A_deaminase_dom.
DR InterPro; IPR006330; Ado/ade_deaminase.
DR InterPro; IPR032466; Metal_Hydrolase.
DR PANTHER; PTHR11409:SF37; A_DEAMINASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11409; ADENOSINE DEAMINASE; 1.
DR Pfam; PF00962; A_deaminase; 1.
DR SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000016933}.
FT DOMAIN 306..596
FT /note="Adenosine deaminase"
FT /evidence="ECO:0000259|Pfam:PF00962"
SQ SEQUENCE 638 AA; 73212 MW; A0B7920ED5159F44 CRC64;
MHVVDKLKDK FGRRKAGQQV TVAETTAAGV SERLTQLDNM DSTADPTAAF DAAFEAYCRE
RDDLIAAERA LAWNQSARSS ATAAEQQAGQ IIWKIRENER VDPRLYGNLP GEEVPGPDKR
DMGGRFLVNK ERIEESKVFK IACRMPKGAH LHLHLNAVLP PEDLMPEARK LTDTFYIRST
KPLVQAEDFI APNTEIVFEV KSKNTKQADI FDPKYVPNPK DPNAVTWMRW ANFRQRFPGT
VPLDQIPFEI DRKQNEDLDN AERWAREKII FTQDRVYNDR QTTNGIWACF NQGTRASKGL
VHYESMFRLY IRRVIDTMIE DKVMYFELRP MLLDKFIPKD DGEGKLDHKA QMNIICEEMK
NKQEELKRDD KIDAFPFGLK VIYATPRSIG KLMMEGELRD CIALKKAYPD LICGFDLVGA
EDRPHNIGYY ADLLLKFVVD SKTEFGEPIP FMFHAGESLL DTGGSHNPEN SNLYDSLLFN
SKRIGHGYAL LKHPVLTQRY RERKICLELC PISNELLGLC GNARQHIFPE LLAAGLQCTL
NADNPNMFRY AGHSRTPLSY EFYQVMVGDP RMDIHGWKQL ALWSIEHSCI SPQQQARAKT
IFMKEWQTFC LSVVEDFGSY ASDMKDLNKS WFPQELGR
//
