ID N1R8U1_FUSC4 Unreviewed; 1099 AA.
AC N1R8U1;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Sodium/potassium-transporting ATPase subunit alpha-2 {ECO:0000313|EMBL:EMT62633.1};
GN ORFNames=FOC4_g10006258 {ECO:0000313|EMBL:EMT62633.1};
OS Fusarium oxysporum f. sp. cubense (strain race 4) (Panama disease fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=2502994 {ECO:0000313|EMBL:EMT62633.1, ECO:0000313|Proteomes:UP000016929};
RN [1] {ECO:0000313|Proteomes:UP000016929}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race 4 {ECO:0000313|Proteomes:UP000016929};
RA Fang X., Huang J.;
RT "Genome sequencing and comparative transcriptomics of race 1 and race 4 of
RT banana pathogen: Fusarium oxysporum f. sp. cubense.";
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000016929}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race 4 {ECO:0000313|Proteomes:UP000016929};
RX PubMed=24743270;
RA Guo L., Han L., Yang L., Zeng H., Fan D., Zhu Y., Feng Y., Wang G.,
RA Peng C., Jiang X., Zhou D., Ni P., Liang C., Liu L., Wang J., Mao C.,
RA Fang X., Peng M., Huang J.;
RT "Genome and Transcriptome Analysis of the Fungal Pathogen Fusarium
RT oxysporum f. sp. cubense Causing Banana Vascular Wilt Disease.";
RL PLoS ONE 9:E95543-E95543(2014).
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DR EMBL; KB726995; EMT62633.1; -; Genomic_DNA.
DR AlphaFoldDB; N1R8U1; -.
DR STRING; 1229665.N1R8U1; -.
DR HOGENOM; CLU_002360_4_1_1; -.
DR Proteomes; UP000016929; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 1.20.1110.10; Calcium-transporting ATPase, transmembrane domain; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR006068; ATPase_P-typ_cation-transptr_C.
DR InterPro; IPR004014; ATPase_P-typ_cation-transptr_N.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR001757; P_typ_ATPase.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01494; ATPase_P-type; 2.
DR PANTHER; PTHR43294:SF22; P-TYPE ATPASE; 1.
DR PANTHER; PTHR43294; SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA; 1.
DR Pfam; PF13246; Cation_ATPase; 1.
DR Pfam; PF00689; Cation_ATPase_C; 1.
DR Pfam; PF00690; Cation_ATPase_N; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR Pfam; PF00702; Hydrolase; 1.
DR PRINTS; PR00119; CATATPASE.
DR PRINTS; PR00121; NAKATPASE.
DR SFLD; SFLDS00003; Haloacid_Dehalogenase; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SMART; SM00831; Cation_ATPase_N; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF81660; Metal cation-transporting ATPase, ATP-binding domain N; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000016929};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 161..181
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 193..212
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 355..378
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 390..413
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 854..876
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 882..903
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 933..954
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 993..1009
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1030..1048
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1060..1078
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 109..182
FT /note="Cation-transporting P-type ATPase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00831"
FT REGION 1..68
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 25..42
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 43..57
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1099 AA; 122450 MW; 2251C681BFF9D91A CRC64;
MSDPDIRGTK ESDPEAQIQR ITFQDGPERG REEHDAHRLG RTLSRSLSRR RSHSSSRSRI
HPTSPYSGVQ IEYRTLSIQV TEAKQVEPTE DSKAAAGQKT DEDYFSKLQY HELQTEQLCQ
QLNVDVGAGL SESSAATRLE RDGKNTLPHP KTNYIKRTLK YIFGGFCSVL WVGAIIFFLC
WQPLSNPPSN QNLSLAVLIL IVIFLQAGFS AFQDWSTAKT MNAILDLLPS FAMVKRDGEL
KSLPTVGLVA GDVVHLKVGD KVPADLRIVS HSGDIRFDRS VLTGESDEIE GAVDATDANF
LESRNIAFMG TTVMNGNGVG VVILTGGRTV MGRIATSTSG VKDSAALIQR EITRFVMIIV
CMTIILALAI LLTWVGWLRV DHHAYMSVPA MLVNVMACVV AFIPEGMPVA VALTLMMIAR
RMKAVNVLPK GLSTVETLGC VNVICSDKTG TLTQNQMFVS SVAFVDKKFD SSDEFQHLLH
SKDVTEPATA LQRAALLCND ASFDPTTNHL PLHERTIQGN ATDSAVFRFA AYGPSGDSFR
KTLPRIFEVP FNSKNKWMLT VFQSDDERGA YRVIIKGAPD ILLAGCTKYW SSESNSVETL
TRDARIKFQE IQDEASRRAE RVIVLCEKFI TPRAVAGTNS FSDEITHSAI QDLTVVGMLG
IIDPHRPEIP ATVEQCRRAG TRFFMVTGDY ALTAAAIARN TGIFSCQQDP DTIDTLYTGN
QITESEKPKR KAKKGDRAEI IKRSLLLEGA NLSRLSQEDW DVVCAYEEIV FARTTPEQKL
RIVTELRERD NVVAVTGDGV NDAPALRAAD VGVAIVTGSD VAIEASDLVL LDRFDSIIDA
MRLGRLVFQN LQKVISYLLP AGSWSEIWPV ILNVWFGVPL PLSAFLMIII CVFTDLFLSL
SLIMEKEEFD LLSLPPRNHK RDHLINAKIY TQAYLFTGFM ETITAHAMFF FYMWKYAKMP
VSELFFLFEG YTEGYRGYTA AELTKFNNTG QCVYFVTLVF LQWGNILAVR NRRLSIFQAN
PLSKAHRNPW LILSMLISLC IAIFVTEVPG IQNLFDTESV PIEFWLIPIP LGLGILLVDE
IRKFIVRTYP KSFVARIAW
//
