ID N1RRR2_FUSC4 Unreviewed; 600 AA.
AC N1RRR2;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=3-oxosteroid 1-dehydrogenase {ECO:0000313|EMBL:EMT66822.1};
GN ORFNames=FOC4_g10000517 {ECO:0000313|EMBL:EMT66822.1};
OS Fusarium oxysporum f. sp. cubense (strain race 4) (Panama disease fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=2502994 {ECO:0000313|EMBL:EMT66822.1, ECO:0000313|Proteomes:UP000016929};
RN [1] {ECO:0000313|Proteomes:UP000016929}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race 4 {ECO:0000313|Proteomes:UP000016929};
RA Fang X., Huang J.;
RT "Genome sequencing and comparative transcriptomics of race 1 and race 4 of
RT banana pathogen: Fusarium oxysporum f. sp. cubense.";
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000016929}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race 4 {ECO:0000313|Proteomes:UP000016929};
RX PubMed=24743270;
RA Guo L., Han L., Yang L., Zeng H., Fan D., Zhu Y., Feng Y., Wang G.,
RA Peng C., Jiang X., Zhou D., Ni P., Liang C., Liu L., Wang J., Mao C.,
RA Fang X., Peng M., Huang J.;
RT "Genome and Transcriptome Analysis of the Fungal Pathogen Fusarium
RT oxysporum f. sp. cubense Causing Banana Vascular Wilt Disease.";
RL PLoS ONE 9:E95543-E95543(2014).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
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DR EMBL; KB726986; EMT66822.1; -; Genomic_DNA.
DR AlphaFoldDB; N1RRR2; -.
DR STRING; 1229665.N1RRR2; -.
DR HOGENOM; CLU_011398_4_2_1; -.
DR Proteomes; UP000016929; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0008202; P:steroid metabolic process; IEA:UniProt.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR PANTHER; PTHR43400:SF7; FAD_BINDING_2 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43400; FUMARATE REDUCTASE; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000016929}.
FT DOMAIN 34..565
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 600 AA; 65679 MW; 51BA423EA973FB53 CRC64;
MPQHNTKPSC PIIRQVSGHR GNSSQYRGSI FECDILIIGA GAAGLAAAAA VQDQGRRVIL
VEKEDYVGGT TFRSGGCMWM PNNFRMQELG IEDSKEQAER YIAAVGKATS PCLDEDIVLR
DLQNRRLKAF LTQGPEMAKY FRNQGFRWMA TPSKFPDYHP HMEGAVAYGR TLDPEVFDAA
SLEGWVRYLQ VQENVPVISR FEDLCVLTRR PFSTGCATKT VAPPQDMERP MSMGQSLIAQ
LLKICKEHSN VTIWTRCELQ ELLVSDLDGR VIGAKVLCGR SEKPVHIHAS LGVVLTTGGF
SQNQKMRDTY LGIGSTDGRA SKISTMAGWS LAAPGDIGIA LQVSQRLHAD SAQLDQVWGI
PTMINPGTGK VTEAMFAISK PFSFVVDGYG RRFFSESQPY GAAVRSMYER AKKGSRTAEF
WLIFDDKYMQ AYPIGGLQSP WLIDQAVEKG LLVRSDTVDG LSKQILVPNQ SLQATLSEWN
EMCDGGRDKH FHRGEDRYQQ FIGDPDVTPN PYMGPVKESP FYAIKIFPGD AGTRGGPLTD
EFARVLRKNG DVIHGLFAGG NASAALLESQ GAGTTLAPAM TEGFIAVTYM LSLASAASSS
//
