ID N1RW54_FUSC4 Unreviewed; 1683 AA.
AC N1RW54;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=Clathrin heavy chain {ECO:0000256|PIRNR:PIRNR002290};
GN ORFNames=FOC4_g10008526 {ECO:0000313|EMBL:EMT70084.1};
OS Fusarium oxysporum f. sp. cubense (strain race 4) (Panama disease fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=2502994 {ECO:0000313|EMBL:EMT70084.1, ECO:0000313|Proteomes:UP000016929};
RN [1] {ECO:0000313|Proteomes:UP000016929}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race 4 {ECO:0000313|Proteomes:UP000016929};
RA Fang X., Huang J.;
RT "Genome sequencing and comparative transcriptomics of race 1 and race 4 of
RT banana pathogen: Fusarium oxysporum f. sp. cubense.";
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000016929}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race 4 {ECO:0000313|Proteomes:UP000016929};
RX PubMed=24743270;
RA Guo L., Han L., Yang L., Zeng H., Fan D., Zhu Y., Feng Y., Wang G.,
RA Peng C., Jiang X., Zhou D., Ni P., Liang C., Liu L., Wang J., Mao C.,
RA Fang X., Peng M., Huang J.;
RT "Genome and Transcriptome Analysis of the Fungal Pathogen Fusarium
RT oxysporum f. sp. cubense Causing Banana Vascular Wilt Disease.";
RL PLoS ONE 9:E95543-E95543(2014).
CC -!- FUNCTION: Clathrin is the major protein of the polyhedral coat of
CC coated pits and vesicles. {ECO:0000256|PIRNR:PIRNR002290}.
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle membrane
CC {ECO:0000256|PIRNR:PIRNR002290}; Peripheral membrane protein
CC {ECO:0000256|PIRNR:PIRNR002290}; Cytoplasmic side
CC {ECO:0000256|PIRNR:PIRNR002290}. Membrane, coated pit
CC {ECO:0000256|PIRNR:PIRNR002290}; Peripheral membrane protein
CC {ECO:0000256|PIRNR:PIRNR002290}; Cytoplasmic side
CC {ECO:0000256|PIRNR:PIRNR002290}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
CC -!- SIMILARITY: Belongs to the clathrin heavy chain family.
CC {ECO:0000256|PIRNR:PIRNR002290}.
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DR EMBL; KB726324; EMT70084.1; -; Genomic_DNA.
DR STRING; 1229665.N1RW54; -.
DR HOGENOM; CLU_002136_0_0_1; -.
DR Proteomes; UP000016929; Unassembled WGS sequence.
DR GO; GO:0030132; C:clathrin coat of coated pit; IEA:InterPro.
DR GO; GO:0030130; C:clathrin coat of trans-Golgi network vesicle; IEA:InterPro.
DR GO; GO:0071439; C:clathrin complex; IEA:InterPro.
DR GO; GO:0032051; F:clathrin light chain binding; IEA:InterPro.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR Gene3D; 1.25.40.730; -; 1.
DR Gene3D; 2.130.10.110; Clathrin heavy-chain terminal domain; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000547; Clathrin_H-chain/VPS_repeat.
DR InterPro; IPR016025; Clathrin_H-chain_N.
DR InterPro; IPR022365; Clathrin_H-chain_propeller_rpt.
DR InterPro; IPR016341; Clathrin_heavy_chain.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR10292:SF1; CLATHRIN HEAVY CHAIN; 1.
DR PANTHER; PTHR10292; CLATHRIN HEAVY CHAIN RELATED; 1.
DR Pfam; PF00637; Clathrin; 7.
DR Pfam; PF13838; Clathrin_H_link; 1.
DR Pfam; PF01394; Clathrin_propel; 3.
DR PIRSF; PIRSF002290; Clathrin_H_chain; 1.
DR SMART; SM00299; CLH; 7.
DR SUPFAM; SSF48371; ARM repeat; 6.
DR SUPFAM; SSF50989; Clathrin heavy-chain terminal domain; 1.
DR PROSITE; PS50236; CHCR; 7.
PE 3: Inferred from homology;
KW Coated pit {ECO:0000256|PIRNR:PIRNR002290};
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329,
KW ECO:0000256|PIRNR:PIRNR002290}; Membrane {ECO:0000256|PIRNR:PIRNR002290};
KW Reference proteome {ECO:0000313|Proteomes:UP000016929}.
FT REGION 1659..1683
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1683 AA; 190601 MW; E901E57DB4520DB6 CRC64;
MPTLPIKFQE LVQLANVGVD TQSIGFNSCT LESDSYVCVR EKKNEAAQPE VVIVELKNGN
NVTRRPIKAD SAIMHWNRQV IALKAQSRTL QIFDLEQKKK LKSCTMNEDV QFWKWISENE
LGLVTTTSVF HWNVYDAGQD APVKVFQRND NLQGCQIINY RVNSDGKWMV VVGISSQQGR
VVGAMQLYSK DRGISQAIEG HAAAFGTLRL EGAPQDTKFF SFAVRTATGA KLHIVEVDHP
ESNPVFQKKA VDMFFPPEAT NDFPVALQVS QKYGVIYMVT KYGFIHLYDL ETASCIYMNR
ISSETIFTTC TDDGSSGIVG INRKGQVLFV TIDDNNIIPY LLQNPANSEM AIKMASRAGL
PGADNLYARQ FEQLFNAGSY LEAAKVAANS PRGFLRSAET IEKFKRLPVQ PGQMAFTLQY
FGMLLDKGAL NREETLELAQ PVLQQNRKHL LEKWLKEGKL DCSEALGDLV RPYDMNMALT
IYLKAEVPAK VVAGFAETGQ FDKILPYSAQ TGYQPDYIQL LQHIIRINPE KGAEFASALA
NNEQGSLVDL ERVCDIFQGQ GMIQQATAFL LDALKENKPE HARLQTRLLE MNLMHAPQVA
EAILGNEMFT HFDKSRIAQL CEQANLPQKA LELYEDPEAI KRVIVNIPGS PNFNPDWLTT
FFGKLSVEQS LDCLDAMMKT NIRQNLQSVV TIATKYSDLL GAVRLIDLFE KYKTAEGLFY
YLGSIVNLSE DPDVHFKYIE AATKMGQFNE VERLCRDSNV YNPEKVKNFL KEAKLPEQLP
LIIVCDRFNF VHDLILYLYQ NQQFAAIETY VQSVNPPRAP EVIGGLLDVD CDENVIKQLL
QTVNAQAISI DSLVSEVESR NRLKLLLPFL EKTLNEGNQQ QAVFNALAKI YIDSNNNPEK
FLKENDQYDT LTVGKYCEKR DPNLAYIAYS KGQNDLELVN ITNENSMYRA QARYLLERSD
AELWGFVLSE NNIHRRSVVD QVTATAVPEA NDPSKVSVAV AAFLENDLPL ELIELLEKIV
LEPSPFSDNQ NLQNLLMFTA AKADKGRVMD YIHKLDNYNA DEIATACIEV GLFEEAFEIY
KKADNKSAAV DVLIENVVSI DRAQGYAEEV DLPEVWSKVA KAQLDGLRIS DAIESYIKAE
DPRNYLEVIE VATHAGKNED LVKYLRMCRK TLREPAIDTA LAFSYARLDQ LSELEDFLRA
TNVANIEESG DKAYEEGLFE ASKIFYTSIS NWAKLATTLV HLGDYQAAVE CARKANNIKV
WKQVHEACVQ KKEFRLAQIC GLNLIVDAEQ LQTLVKEYER NGYFDELISL LEQGLGLERA
HMGMFTELGI ALSKYHPDRL MEHIKIFWSR MNLPKMIKAC EEANLWPELV FCYYHYDEFD
NAALAVIERP ENSWDHQQFK EIVVKVANLE IYYRAIKFYV EQHPSLITDL LATLTPRIDV
NRVVKIFQKN DDLPLIKPFL LNVQTQNKRV VNEAVNDLLI EEEDYKTLRD SVQNYDNYDA
TELASRLEKH DLIFFRQIAA SIYRKNKRWE KSIALSKQDK LYKDAIETAA LSAKTEIVSD
LLQYFVDIGH RECYTGMLYA CYELIRPDLV LELSWRHGLM DFSMPYMINM LAQQTKDLAL
LKADNEARKA KEQEKEKTDD NTPILGASRL MITAGPGGMG SSPSPAPYGQ ANGFAPQPTG
YGF
//
