ID   N1RWH5_FUSC4            Unreviewed;       691 AA.
AC   N1RWH5;
DT   26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 1.
DT   24-JAN-2024, entry version 40.
DE   RecName: Full=DENN domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=FOC4_g10012974 {ECO:0000313|EMBL:EMT68557.1};
OS   Fusarium oxysporum f. sp. cubense (strain race 4) (Panama disease fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC   Fusarium oxysporum species complex.
OX   NCBI_TaxID=2502994 {ECO:0000313|EMBL:EMT68557.1, ECO:0000313|Proteomes:UP000016929};
RN   [1] {ECO:0000313|Proteomes:UP000016929}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=race 4 {ECO:0000313|Proteomes:UP000016929};
RA   Fang X., Huang J.;
RT   "Genome sequencing and comparative transcriptomics of race 1 and race 4 of
RT   banana pathogen: Fusarium oxysporum f. sp. cubense.";
RL   Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000016929}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=race 4 {ECO:0000313|Proteomes:UP000016929};
RX   PubMed=24743270;
RA   Guo L., Han L., Yang L., Zeng H., Fan D., Zhu Y., Feng Y., Wang G.,
RA   Peng C., Jiang X., Zhou D., Ni P., Liang C., Liu L., Wang J., Mao C.,
RA   Fang X., Peng M., Huang J.;
RT   "Genome and Transcriptome Analysis of the Fungal Pathogen Fusarium
RT   oxysporum f. sp. cubense Causing Banana Vascular Wilt Disease.";
RL   PLoS ONE 9:E95543-E95543(2014).
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DR   EMBL; KB726554; EMT68557.1; -; Genomic_DNA.
DR   AlphaFoldDB; N1RWH5; -.
DR   HOGENOM; CLU_398502_0_0_1; -.
DR   Proteomes; UP000016929; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd00029; C1; 1.
DR   Gene3D; 3.40.50.11500; -; 1.
DR   InterPro; IPR046349; C1-like_sf.
DR   InterPro; IPR001194; cDENN_dom.
DR   InterPro; IPR005112; dDENN_dom.
DR   InterPro; IPR043153; DENN_C.
DR   InterPro; IPR002219; PE/DAG-bd.
DR   InterPro; IPR037516; Tripartite_DENN.
DR   PANTHER; PTHR12296:SF21; DENN DOMAIN-CONTAINING PROTEIN 3; 1.
DR   PANTHER; PTHR12296; DENN DOMAIN-CONTAINING PROTEIN 4; 1.
DR   Pfam; PF03455; dDENN; 1.
DR   Pfam; PF02141; DENN; 1.
DR   SMART; SM00801; dDENN; 1.
DR   SMART; SM00799; DENN; 1.
DR   SUPFAM; SSF57889; Cysteine-rich domain; 1.
DR   PROSITE; PS50211; DENN; 1.
DR   PROSITE; PS50081; ZF_DAG_PE_2; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016929};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          1..559
FT                   /note="UDENN"
FT                   /evidence="ECO:0000259|PROSITE:PS50211"
FT   DOMAIN          426..474
FT                   /note="Phorbol-ester/DAG-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50081"
FT   REGION          238..312
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          326..346
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        274..312
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        326..343
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   691 AA;  75949 MW;  82EEFD906738B1A2 CRC64;
     MTDGGVLRIP PSSPSVGRWQ PLERYVVNLC TEAFNPLGSK TQVELGVREL RLYARKEADN
     EIPGSRSIDL YALFRCLSLE NIVALFEYAM AESRIIFLSS HTSMLHLACH ALANLLYPLK
     WSSIFIPVLP ARLLSALEAP CPYIVGIERR YDRIELPEDD YVLVDLDKDT IDATSQPVRL
     PRQARRKLMS LLQVAAPHKL RYGVTTGPPP YAMESFPYDA FSTENAALFR SATPKSTLGK
     WVSQSSSGFG EPDPPNEVLP PLFNAFASAK VDNGKSDRPS TSKSGKTSPQ SSVSPVSINF
     PPMPSTPVSR SDSGFALAAT LREKRSGHFG EEKMRRSSSF GIDKHPPYHK PNLPFLNGHQ
     ANLSISAISV DSQNSVVGGG SSGGGGYGNG YAPSTYAQST LAASTIMPSM QIQPVRNTET
     TVWVEGHCFN WIPKDNTSIC NICNDHAEGD GIYKCTGCKI FSHGRCLGHA SLVCPEAFHP
     DRIRAAFVRC LASLLYTYRK YLGRPSKQQK ANGQLYAFDM DGFIKSLPHD QHDYATMMRE
     TQCFNEFIHD REMQPANNAS IRVFDEIIMA KKARGRSGLS TGLSRLSTIR ASHGASTYGG
     YAPPRGSSNS KIPAWLGDTS DHIWRTASVP LPKGNFPGEY RTVVTRTPAR LDRSLMREPR
     SIQGMPRVEG RGARGLIRKQ VPSMLGTTPP T
//