ID   N1U3U5_9LEPT            Unreviewed;       684 AA.
AC   N1U3U5;
DT   26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 1.
DT   24-JAN-2024, entry version 34.
DE   SubName: Full=Alpha-2-macroglobulin MG1 domain protein {ECO:0000313|EMBL:EMY12584.1};
GN   ORFNames=LEP1GSC043_3236 {ECO:0000313|EMBL:EMY12584.1};
OS   Leptospira weilii str. Ecochallenge.
OC   Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC   Leptospira.
OX   NCBI_TaxID=1049986 {ECO:0000313|EMBL:EMY12584.1, ECO:0000313|Proteomes:UP000012249};
RN   [1] {ECO:0000313|EMBL:EMY12584.1, ECO:0000313|Proteomes:UP000012249}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ecochallenge {ECO:0000313|EMBL:EMY12584.1,
RC   ECO:0000313|Proteomes:UP000012249};
RA   Harkins D.M., Durkin A.S., Brinkac L.M., Haft D.H., Selengut J.D.,
RA   Sanka R., DePew J., Purushe J., Haake D.A., Matsunaga J., Vinetz J.M.,
RA   Sutton G.G., Nierman W.C., Fouts D.E.;
RL   Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EMY12584.1}.
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DR   EMBL; AHMI02000290; EMY12584.1; -; Genomic_DNA.
DR   AlphaFoldDB; N1U3U5; -.
DR   Proteomes; UP000012249; Unassembled WGS sequence.
DR   GO; GO:0004866; F:endopeptidase inhibitor activity; IEA:InterPro.
DR   Gene3D; 2.60.40.1930; -; 1.
DR   InterPro; IPR021868; Alpha_2_Macroglob_MG3.
DR   InterPro; IPR002890; MG2.
DR   PANTHER; PTHR40094; ALPHA-2-MACROGLOBULIN HOMOLOG; 1.
DR   PANTHER; PTHR40094:SF1; UBIQUITIN DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF11974; bMG3; 1.
DR   Pfam; PF01835; MG2; 1.
PE   4: Predicted;
FT   DOMAIN          183..290
FT                   /note="Alpha-2-macroglobulin MG3"
FT                   /evidence="ECO:0000259|Pfam:PF11974"
FT   DOMAIN          301..396
FT                   /note="Macroglobulin"
FT                   /evidence="ECO:0000259|Pfam:PF01835"
SQ   SEQUENCE   684 AA;  76883 MW;  B85A498D161E251E CRC64;
     MVSTDDYPPL LKFSSKFGIL ERFPEAILPV TIRNLEAENP VRLYQVKTSP DTENVIKEQF
     DKLKEKGKEI FNWATGKEEK PNLPKQFTGK ELILGSGQIA EIVRFLKTIE SLEHSHSIFD
     SSQNPPPTNE IKLQSKQGVR RFEVVGIPLK KPGFHVVEMK SDVLGNSLLE INQPFYVRTA
     ALVTNLSLHF KWGNESSLVW VTKLNDAKPV PGADIQIFNC KNERIFVGKT GPEGILLVKG
     IPPRNEVPYC SWKAYENGLL LTAAFEDDFT FTHTRWRNGI ENWRFNLPGD SGENNVLFHP
     VLDRTLFRAG ETVSMKVISR TKRSHGFEVP GQKDYPAFAK IVHSGSDKEY SISLKWNQEG
     TSSLQFKIPK EANLGVYQIE FANKNNDLVS IGEFRVEEFR IPLMKADFQV SGPNVGPSQL
     ELSGNVRYLS GGGAGKLPVL LRTRVTVGGG VFFPDYSDFS FSNGLVNRKS EENEEPISVV
     GFTKTQLTLD EKGFFETTVK SIPESNTIQK LEAELEYKDP NGEIQSAFRS FPIYPSEYHI
     GIARESWAAV QDSVRLKVAV LDLKGTPIEG KKINVVAFTK KYYSNRKRLV GGFYSYEHKY
     EVNELGEFCS GKTNAKGIVF CSGPVNTTGE VHFEASLSGE DVKANSSVWI SGKEDFWFAA
     SDHDRMDLLP EKKNTRRVKK PGFK
//