ID N1U7Q4_9LEPT Unreviewed; 639 AA.
AC N1U7Q4;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 24-JAN-2024, entry version 47.
DE RecName: Full=Flagellar hook-associated protein 2 {ECO:0000256|RuleBase:RU362066};
DE Short=HAP2 {ECO:0000256|RuleBase:RU362066};
DE AltName: Full=Flagellar cap protein {ECO:0000256|RuleBase:RU362066};
GN Name=fliD {ECO:0000313|EMBL:EMY14226.1};
GN ORFNames=LEP1GSC043_4543 {ECO:0000313|EMBL:EMY14226.1};
OS Leptospira weilii str. Ecochallenge.
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptospira.
OX NCBI_TaxID=1049986 {ECO:0000313|EMBL:EMY14226.1, ECO:0000313|Proteomes:UP000012249};
RN [1] {ECO:0000313|EMBL:EMY14226.1, ECO:0000313|Proteomes:UP000012249}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ecochallenge {ECO:0000313|EMBL:EMY14226.1,
RC ECO:0000313|Proteomes:UP000012249};
RA Harkins D.M., Durkin A.S., Brinkac L.M., Haft D.H., Selengut J.D.,
RA Sanka R., DePew J., Purushe J., Haake D.A., Matsunaga J., Vinetz J.M.,
RA Sutton G.G., Nierman W.C., Fouts D.E.;
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for morphogenesis and for the elongation of the
CC flagellar filament by facilitating polymerization of the flagellin
CC monomers at the tip of growing filament. Forms a capping structure,
CC which prevents flagellin subunits (transported through the central
CC channel of the flagellum) from leaking out without polymerization at
CC the distal end. {ECO:0000256|RuleBase:RU362066}.
CC -!- SUBUNIT: Homopentamer. {ECO:0000256|ARBA:ARBA00011255,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000256|RuleBase:RU362066}.
CC Periplasmic flagellum {ECO:0000256|RuleBase:RU362066}.
CC -!- SIMILARITY: Belongs to the FliD family. {ECO:0000256|ARBA:ARBA00009764,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMY14226.1}.
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DR EMBL; AHMI02000183; EMY14226.1; -; Genomic_DNA.
DR AlphaFoldDB; N1U7Q4; -.
DR Proteomes; UP000012249; Unassembled WGS sequence.
DR GO; GO:0009421; C:bacterial-type flagellum filament cap; IEA:InterPro.
DR GO; GO:0009424; C:bacterial-type flagellum hook; IEA:UniProtKB-UniRule.
DR GO; GO:0055040; C:periplasmic flagellum; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR InterPro; IPR040026; FliD.
DR InterPro; IPR010809; FliD_C.
DR InterPro; IPR003481; FliD_N.
DR PANTHER; PTHR30288; FLAGELLAR CAP/ASSEMBLY PROTEIN FLID; 1.
DR PANTHER; PTHR30288:SF0; FLAGELLAR HOOK-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF07195; FliD_C; 1.
DR Pfam; PF02465; FliD_N; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum {ECO:0000256|ARBA:ARBA00023143,
KW ECO:0000256|RuleBase:RU362066};
KW Cell projection {ECO:0000313|EMBL:EMY14226.1};
KW Cilium {ECO:0000313|EMBL:EMY14226.1};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|RuleBase:RU362066};
KW Flagellum {ECO:0000313|EMBL:EMY14226.1};
KW Periplasm {ECO:0000256|RuleBase:RU362066}.
FT DOMAIN 11..107
FT /note="Flagellar hook-associated protein 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02465"
FT DOMAIN 363..623
FT /note="Flagellar hook-associated protein 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07195"
FT COILED 580..607
FT /evidence="ECO:0000256|RuleBase:RU362066"
SQ SEQUENCE 639 AA; 69643 MW; CF6A682A8733D617 CRC64;
MPAFTIPGLS SGQDTNLIVK KLVELEAKPI RRLEQQNSFN KAQVKAWNGL QEVTTDLQNK
TRALISFTAP FAMKNIVSEP EGVVSGDASR SASAGKRKIE IKELATYHQI SGEKTDANKQ
IPAGKFKIFS GDSEKEIEFS GGTIRDLASS IKISAAGLVN TGLVKVDGDN YVLTLTAGLS
GKDRKLKFED SNGILQAANL VGATEPADPP KVLNFFPEAD QVSVFQPEKY GIATDAKPIY
KEENNKKWME IAGVGSFQFG IITTELKKNT RIELVTSTEF APEDKLELGI LYKENDKEKM
IFETASKQEG KIVLNLKAFP SGQKAHKILF ANSSGKAVIL DSFHVVIPGE FRGAKPAKEI
AEAKDAVFLV DGIEVNRPKN EGLTDVLDGV SLNLLKKTEG PVSIDIRTDS DKGLEMIKEF
VASYNTVLKF GKDATAVDKN AQVKDGKEDS GEISQSYWEG KSKTGLLSGE HTVLRLIAGM
KTVASSSYPV GGENPVKMLS DIGISTGNVG SKWADIQDGF LILDEEKLRS KLAENPDSVR
NLFAIDTNSD ARMDTGVAVD LLEHIKPYTQ YAGGLVSGKV KMLEEQVTDN NKKIKEYENH
LASYEKKLKS KFLYMEQGVG KNKAVGAYLN NNLKGAKNE
//
