ID   N1U860_9LEPT            Unreviewed;       719 AA.
AC   N1U860;
DT   26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   SubName: Full=Cyclic nucleotide-binding domain protein {ECO:0000313|EMBL:EMY14134.1};
GN   ORFNames=LEP1GSC043_2791 {ECO:0000313|EMBL:EMY14134.1};
OS   Leptospira weilii str. Ecochallenge.
OC   Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC   Leptospira.
OX   NCBI_TaxID=1049986 {ECO:0000313|EMBL:EMY14134.1, ECO:0000313|Proteomes:UP000012249};
RN   [1] {ECO:0000313|EMBL:EMY14134.1, ECO:0000313|Proteomes:UP000012249}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ecochallenge {ECO:0000313|EMBL:EMY14134.1,
RC   ECO:0000313|Proteomes:UP000012249};
RA   Harkins D.M., Durkin A.S., Brinkac L.M., Haft D.H., Selengut J.D.,
RA   Sanka R., DePew J., Purushe J., Haake D.A., Matsunaga J., Vinetz J.M.,
RA   Sutton G.G., Nierman W.C., Fouts D.E.;
RL   Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EMY14134.1}.
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DR   EMBL; AHMI02000194; EMY14134.1; -; Genomic_DNA.
DR   AlphaFoldDB; N1U860; -.
DR   Proteomes; UP000012249; Unassembled WGS sequence.
DR   CDD; cd00038; CAP_ED; 2.
DR   CDD; cd07738; DdPDE5-like_MBL-fold; 1.
DR   Gene3D; 2.60.120.10; Jelly Rolls; 2.
DR   Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR   InterPro; IPR018488; cNMP-bd_CS.
DR   InterPro; IPR000595; cNMP-bd_dom.
DR   InterPro; IPR018490; cNMP-bd_dom_sf.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   PANTHER; PTHR11635:SF168; CAMP PROTEIN KINASE REGULATORY CHAIN; 1.
DR   PANTHER; PTHR11635; CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN; 1.
DR   Pfam; PF00027; cNMP_binding; 2.
DR   Pfam; PF00753; Lactamase_B; 1.
DR   PRINTS; PR00103; CAMPKINASE.
DR   SMART; SM00100; cNMP; 2.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF51206; cAMP-binding domain-like; 2.
DR   SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
DR   PROSITE; PS00888; CNMP_BINDING_1; 1.
DR   PROSITE; PS00889; CNMP_BINDING_2; 1.
DR   PROSITE; PS50042; CNMP_BINDING_3; 2.
PE   4: Predicted;
FT   DOMAIN          472..576
FT                   /note="Cyclic nucleotide-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS50042"
FT   DOMAIN          605..719
FT                   /note="Cyclic nucleotide-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS50042"
SQ   SEQUENCE   719 AA;  82473 MW;  5C24026CC1D38DBD CRC64;
     MLKETYKGYT ELPRGGYLID TSEGYLQIGS PPETIKDTMG FEKKTPLVFI LPNKFFHVEK
     GISTAELEFP IYYNFFLRQK KTFIVCTKEQ KVQLITVLKE SLMGPDNINL KSEYLNGEES
     FGFPDMKAEM AYFRGYKGLD DVVEFKVFDN DNKVYYGNVN ILKLESGDFL IQDGEKKIEV
     PGEVGFNIKY DIGERPTEPF QAPIIGITCL GPSHGFDPED NTSGFIIWLN HQGIMVDPPV
     NSTEWLRQSN VNPKLINHVI LTHCHADHDA GTFQKILEEN KITIHATETV IDSFLRKYSA
     LTKIPKKELQ ELFHFQPIII GKATMINGGE FNFHYALHSI PSVGFEFFFQ DQSFIYTSDH
     LNEPEIHDKM HAAGILPESR WKFFKEFPWD RRIIYHEAGI PPLHTRVSYL ASLPEEIQEK
     ITVYHIARKD MPTGTKLKLA KFGIENTLYP EITPPKHIEA YNLLDVMTQI DIFQGFPIEK
     AKEFLLIVNE ERYKRGDQII RKGTPGDKFY IIASGNVKFE GLNQDGSEGV PVKRYGTYEY
     FGEASLVLDL PRAADVYAET DVLALTIEKN KFLQFIRNSD LKNNLTKLNE IRDSNSWKAL
     AESRHFRGLT SHQITQLELI MTLHKVNAGS ILVKEKEFYG DAYIIRSGKV NVYQEGNLLA
     ELTDGDFVGE IYNISKSFVS NYTFQAEIDT ELYSIQQNDL IDYVKKNPGV YMRMNTVYS
//