ID N1UB70_9LEPT Unreviewed; 401 AA.
AC N1UB70;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Crotonyl-CoA reductase {ECO:0000313|EMBL:EMY15209.1};
GN Name=ccrA {ECO:0000313|EMBL:EMY15209.1};
GN ORFNames=LEP1GSC043_0373 {ECO:0000313|EMBL:EMY15209.1};
OS Leptospira weilii str. Ecochallenge.
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptospira.
OX NCBI_TaxID=1049986 {ECO:0000313|EMBL:EMY15209.1, ECO:0000313|Proteomes:UP000012249};
RN [1] {ECO:0000313|EMBL:EMY15209.1, ECO:0000313|Proteomes:UP000012249}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ecochallenge {ECO:0000313|EMBL:EMY15209.1,
RC ECO:0000313|Proteomes:UP000012249};
RA Harkins D.M., Durkin A.S., Brinkac L.M., Haft D.H., Selengut J.D.,
RA Sanka R., DePew J., Purushe J., Haake D.A., Matsunaga J., Vinetz J.M.,
RA Sutton G.G., Nierman W.C., Fouts D.E.;
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homotetramer. {ECO:0000256|ARBA:ARBA00011881}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMY15209.1}.
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DR EMBL; AHMI02000106; EMY15209.1; -; Genomic_DNA.
DR AlphaFoldDB; N1UB70; -.
DR Proteomes; UP000012249; Unassembled WGS sequence.
DR GO; GO:0043880; F:crotonyl-CoA reductase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd08246; crotonyl_coA_red; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR010085; Crot_CoA_red.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR InterPro; IPR002364; Quin_OxRdtase/zeta-crystal_CS.
DR NCBIfam; TIGR01751; crot-CoA-red; 1.
DR PANTHER; PTHR44154; QUINONE OXIDOREDUCTASE; 1.
DR PANTHER; PTHR44154:SF1; QUINONE OXIDOREDUCTASE; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS01162; QOR_ZETA_CRYSTAL; 1.
PE 4: Predicted;
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 19..382
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 401 AA; 44046 MW; A2CFB842C20B20B2 CRC64;
MGQVPKKMYA QVVRPERFGD PIKAIQEELI DVPEIAPDEV LVAVMAAGVN YNNVWAALGF
PVDVIGARNK KGEPEKFHIG GSDASGIVYK VGSEVKNVKV GDEVVLHCGI WDKNDPWVKA
GKDPMFAPSQ LIWGYETNWG SFAQFCKVQD HQCLPKPKHL SWEEAAAYML VGATAYRMLH
HWKPNDVQKD DVVLIWGGAG GLGAMAIQIV KAAGGVPIAV VSEDDKFDFC KKLGAAGVIN
RKKFDHWGAL TSEINKMEKF AEWTKSAREF GKAIWDIAGK GNNPKIVFEH PGETTIPTSM
FVCETGGMVV ICAGTTGYNA TVDLRYLWMR QKRLQGSHFA NDDNSKGLND LVIDKKVDPC
LSKTFAWNET AHSHQLMKEN KHPAGNMSIL VGADKPGLGK K
//
