ID N1UI33_9LEPT Unreviewed; 259 AA.
AC N1UI33;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 24-JAN-2024, entry version 53.
DE SubName: Full=Acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase {ECO:0000313|EMBL:EMY15685.1};
DE EC=2.3.1.129 {ECO:0000313|EMBL:EMY15685.1};
GN Name=lpxA {ECO:0000313|EMBL:EMY15685.1};
GN ORFNames=LEP1GSC043_0401 {ECO:0000313|EMBL:EMY15685.1};
OS Leptospira weilii str. Ecochallenge.
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptospira.
OX NCBI_TaxID=1049986 {ECO:0000313|EMBL:EMY15685.1, ECO:0000313|Proteomes:UP000012249};
RN [1] {ECO:0000313|EMBL:EMY15685.1, ECO:0000313|Proteomes:UP000012249}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ecochallenge {ECO:0000313|EMBL:EMY15685.1,
RC ECO:0000313|Proteomes:UP000012249};
RA Harkins D.M., Durkin A.S., Brinkac L.M., Haft D.H., Selengut J.D.,
RA Sanka R., DePew J., Purushe J., Haake D.A., Matsunaga J., Vinetz J.M.,
RA Sutton G.G., Nierman W.C., Fouts D.E.;
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMY15685.1}.
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DR EMBL; AHMI02000069; EMY15685.1; -; Genomic_DNA.
DR AlphaFoldDB; N1UI33; -.
DR Proteomes; UP000012249; Unassembled WGS sequence.
DR GO; GO:0008780; F:acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0009245; P:lipid A biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd03351; LbH_UDP-GlcNAc_AT; 1.
DR Gene3D; 2.160.10.10; Hexapeptide repeat proteins; 1.
DR Gene3D; 1.20.1180.10; Udp N-acetylglucosamine O-acyltransferase, C-terminal domain; 1.
DR InterPro; IPR029098; Acetyltransf_C.
DR InterPro; IPR037157; Acetyltransf_C_sf.
DR InterPro; IPR001451; Hexapep.
DR InterPro; IPR010137; Lipid_A_LpxA.
DR InterPro; IPR011004; Trimer_LpxA-like_sf.
DR NCBIfam; TIGR01852; lipid_A_lpxA; 1.
DR PANTHER; PTHR43480; ACYL-[ACYL-CARRIER-PROTEIN]--UDP-N-ACETYLGLUCOSAMINE O-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR43480:SF1; ACYL-[ACYL-CARRIER-PROTEIN]--UDP-N-ACETYLGLUCOSAMINE O-ACYLTRANSFERASE, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF13720; Acetyltransf_11; 1.
DR Pfam; PF00132; Hexapep; 1.
DR PIRSF; PIRSF000456; UDP-GlcNAc_acltr; 1.
DR SUPFAM; SSF51161; Trimeric LpxA-like enzymes; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000313|EMBL:EMY15685.1};
KW Lipid A biosynthesis {ECO:0000256|ARBA:ARBA00022556};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EMY15685.1}.
FT DOMAIN 175..255
FT /note="UDP N-acetylglucosamine O-acyltransferase C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF13720"
SQ SEQUENCE 259 AA; 28356 MW; 459A9D3EDE70D0C0 CRC64;
MKIHPTAVID PKTELHESVE VGPYSIIEGH VSIQEGTVIE SHVKICAGSE IGKFNRFHQG
AVIGVMPQDL GFNQQLLTRT VIGDHNIFRE YSNIHKGTKE NSPTVIGNKN YFMGNCHVGH
DCILGNNNIL THGCVLAGHV TLGNFVFISG LVAVHQFCFV GDYAMVAGLA KIVQDVPPYS
TVDGNPSTVV GLNSVGMKRA GFSPEVRNII KQAYKIIYHS GMPTRKALDE LEASGNLIDE
VKYIIKFFRD SDRGVTSHR
//
