ID   N1V489_9MICC            Unreviewed;      1198 AA.
AC   N1V489;
DT   26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   RecName: Full=Nuclease {ECO:0008006|Google:ProtNLM};
GN   ORFNames=D477_007801 {ECO:0000313|EMBL:EMY34804.1};
OS   Arthrobacter crystallopoietes BAB-32.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC   Arthrobacter.
OX   NCBI_TaxID=1246476 {ECO:0000313|EMBL:EMY34804.1, ECO:0000313|Proteomes:UP000010729};
RN   [1] {ECO:0000313|EMBL:EMY34804.1, ECO:0000313|Proteomes:UP000010729}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BAB-32 {ECO:0000313|EMBL:EMY34804.1,
RC   ECO:0000313|Proteomes:UP000010729};
RX   PubMed=23833141;
RA   Joshi M.N., Pandit A.S., Sharma A., Pandya R.V., Desai S.M., Saxena A.K.,
RA   Bagatharia S.B.;
RT   "Draft Genome Sequence of Arthrobacter crystallopoietes Strain BAB-32,
RT   Revealing Genes for Bioremediation.";
RL   Genome Announc. 1:e00452-13(2013).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EMY34804.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; ANPE02000100; EMY34804.1; -; Genomic_DNA.
DR   RefSeq; WP_005268409.1; NZ_ANPE02000100.1.
DR   AlphaFoldDB; N1V489; -.
DR   OrthoDB; 9757917at2; -.
DR   Proteomes; UP000010729; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd17934; DEXXQc_Upf1-like; 1.
DR   CDD; cd18808; SF1_C_Upf1; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR041679; DNA2/NAM7-like_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR019993; RecB_nuclease_TM0106_put.
DR   InterPro; IPR047187; SF1_C_Upf1.
DR   InterPro; IPR038720; YprB_RNase_H-like_dom.
DR   NCBIfam; TIGR03491; TM0106 family RecB-like putative nuclease; 1.
DR   PANTHER; PTHR43788; DNA2/NAM7 HELICASE FAMILY MEMBER; 1.
DR   PANTHER; PTHR43788:SF6; RECBCD ENZYME SUBUNIT RECD; 1.
DR   Pfam; PF13087; AAA_12; 1.
DR   Pfam; PF13604; AAA_30; 1.
DR   Pfam; PF13482; RNase_H_2; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000010729}.
FT   DOMAIN          338..531
FT                   /note="YprB ribonuclease H-like"
FT                   /evidence="ECO:0000259|Pfam:PF13482"
FT   DOMAIN          981..1154
FT                   /note="DNA2/NAM7 helicase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13087"
SQ   SEQUENCE   1198 AA;  131122 MW;  11CECFF1B2E528D5 CRC64;
     MFLLDPLQPG APRELIFTAS DLVVAAQCEY QLLRKLDEKL GRSPKAEFEP DEMLARTAAL
     GDVHEHSVLQ DFRDRFGPGV VEISEITGYT RPLLEDKHAE SMEALRSGAD VVFQASFFDG
     SFHGRSDFLV KEQDGGTARY AVYDTKLARH AKVTALLQLA AYGDQLLKAG IAPSPTVTLV
     LGNRSRSDHS LQDLLPVFRE RRDRFLELTA DHRAQPDPVA WGDERYTACG RCDYCAEQVA
     LHRDLRLVSR MGSTRRRKLH ALGITTIDLL AAMELPAGES PDGALARLRD QARMQTGLAE
     PDGAVEYTDG DGTAHRLAYR LLEANALGTL PRSSEGDIFF DFEGDPLWQD QTGEWGLEYL
     FGVMENPADP GAVPPFRPFW AHSRAEEGKA LADFLDYVAR RRQQFPDLHI YHYANYEKAA
     LRRLSLQHVI GEDAVDTLLR EGVLVDLYDV VRNSLRISEK SYSIKKLEPL YMGDNLRAGE
     VKDAGASVIA YALYCEARDS GRAAEAERIL ASIRDYNEYD CLSTLRLRNW LLELADKRGI
     PRAQPPAAAA ERAPDDPSPE EARLLEHVAA ATERALHAGR EISAADQAVA MVAASVGYHR
     REDKQFWWGH FDRLNAPLSD WWETRDVFTV ESGEVLQDWA KPSPRKNPVR RLRLTGTLAP
     GSTIKEGTKL CRVYDPPLPR HLYDQDTGVN YRGFCFGSEV VGLDAVGDKD VVLLDERLPR
     TAEEYHELPM ALTPDQPPSS KPLREALSAL AAEVGRNLPR LPQQPALDLL QRLRPRLATL
     PALPQVGEGA DAYIDAIAAA VADLDHSYLA VQGPPGSGKT HVGAHVIGRL VERGWKIGVV
     AQSHAVVEHM MTAAIEKGGV PLDRVAKKSN GNPVPWHQTT DADVARLLGA AGGALVGGTA
     WTMTGSNVPA GSLDLLVIDE AGQFSLANTL AVSQAARRLL LLGDPQQLPQ VTQGTHPEPV
     DQSALGWLSA GHATLPEELG YFLALSWRMH PDLCQAVSEL SYEGRLSSAS AASGRLLEGA
     APGVECVLLE HSGNSTSSPE EAGEVVRQVR RHLGLPWTDP QAGPSARPLA QADILVVAPY
     NAQVQLIRHC LEADGLPDVR VGTVDKFQGR EAPVVIISTA VSDATRALRG MDFVLNRNRM
     NVAVSRGQWR AVIVRSQALT GYLPARPEGL EELGAFIGLC MPDPSQSSTG RRRLEHDV
//