ID N2A0Z2_9FIRM Unreviewed; 466 AA.
AC N2A0Z2;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Sugar (Glycoside-Pentoside-Hexuronide) transporter {ECO:0000313|EMBL:EMZ22957.1};
GN ORFNames=C823_03727 {ECO:0000313|EMBL:EMZ22957.1};
OS Eubacterium plexicaudatum ASF492.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC Eubacterium.
OX NCBI_TaxID=1235802 {ECO:0000313|EMBL:EMZ22957.1, ECO:0000313|Proteomes:UP000012589};
RN [1] {ECO:0000313|EMBL:EMZ22957.1, ECO:0000313|Proteomes:UP000012589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ASF492 {ECO:0000313|EMBL:EMZ22957.1,
RC ECO:0000313|Proteomes:UP000012589};
RX PubMed=24723722;
RA Wannemuehler M.J., Overstreet A.M., Ward D.V., Phillips G.J.;
RT "Draft genome sequences of the altered schaedler flora, a defined bacterial
RT community from gnotobiotic mice.";
RL Genome Announc. 2:e00287-e00214(2014).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC -!- SIMILARITY: Belongs to the sodium:galactoside symporter (TC 2.A.2)
CC family. {ECO:0000256|ARBA:ARBA00009617}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMZ22957.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AQFT01000114; EMZ22957.1; -; Genomic_DNA.
DR RefSeq; WP_004065676.1; NZ_AQFT02000001.1.
DR AlphaFoldDB; N2A0Z2; -.
DR STRING; 1235802.C823_03727; -.
DR GeneID; 78433637; -.
DR PATRIC; fig|1235802.3.peg.3932; -.
DR eggNOG; COG2211; Bacteria.
DR HOGENOM; CLU_027408_0_0_9; -.
DR OrthoDB; 9764596at2; -.
DR Proteomes; UP000012589; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015293; F:symporter activity; IEA:InterPro.
DR GO; GO:0008643; P:carbohydrate transport; IEA:InterPro.
DR GO; GO:0006814; P:sodium ion transport; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR039672; MFS_2.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR001927; Na/Gal_symport.
DR NCBIfam; TIGR00792; gph; 1.
DR PANTHER; PTHR11328:SF24; INNER MEMBRANE SYMPORTER YICJ-RELATED; 1.
DR PANTHER; PTHR11328; MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13347; MFS_2; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000012589};
KW Symport {ECO:0000256|ARBA:ARBA00022847};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022847}.
FT TRANSMEM 50..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 92..113
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 119..147
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 159..178
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 190..210
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 250..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 284..304
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 316..333
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 339..367
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 388..410
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 430..449
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 466 AA; 50398 MW; A4FAFA8AAB62836D CRC64;
MSGKPLGKDR FGIQKVMRGS DYFGDAMGQF ALNAINGMVG QLTYFYTDKA GLAAAMVATV
FMITKIVDAF TDIIMGNIVD HTKPGKERYR PWILKMSLPA AVLLLMLFTV PQGNSTLQIA
YMLVTNLLMT SVIYTAIAIP YASLLVVRTN SSEERGKMGV YRALAGYVPG MAIVLAVIPV
TNALGGTQSA WIKFAAIVAL ISLLCLLLCY KKSRETATAD TAAEVLPKKQ EFDEAVPLGE
AVAKLFGNKY WVLALIMGLL SNVTYGLANS SGTYYCKWIY GDDNLVAILG AVGMIPTILG
FILVGPMNKK LGVVKTLRAC FFLGMAATAL RLLNPTHFWY NTILGCVSSF ANIPMMCLLG
VTTAMAIDYN AYKYGNRMVA SSQSAVGFGG KVGNGLGVSV IGWCLAIAHY DATAAVASTA
TKQAIYAFNI YIPLILFLGM FICAIKFDLE TKLPEIREEL EKRGDR
//
